Eny Maria Goloni Bertollo in research grants and scholarships supported by FAPESP.
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Loco-regional invasion and metastasis are the major causes of morbidity and mortality in most solid tumors, including head and neck squamous cell carcinomas (HNSCC). The sustained incidence and shifting epidemiological profile of HNSCC associated with the poor and marginally improved 5-year survival rates, high recurrence and severe functional and psychological negative consequences affec…
Head and neck cancer is a malignant tumor class that affects the regions of the mouth, larynx, and nasopharynx. This heterogeneity of head and neck tumors has made difficult the early diagnosis and prognosis of the disease. The analysis at the molecular level is now an indispensable tool in the fight against cancer. The identification of biomarkers can define cellular and molecular change…
Background: Overexpression of proangiogenic vascular endothelial growth factor A family VEGFAxxx is associated with tumor growth and metastasis. The role of the alternatively spliced antiangiogenic family VEGFAxxxb is poorly investigated in head and neck squamous cell carcinoma (HNSCC). The antiangiogenic isoform binds to bevacizumab and the expression level in HNSCC could influence the t…
Introduction: Angiogenesis is one of the main processes involved in cancer development. In view of this, it is important to identify angiogenic biomarkers that can help in early diagnosis of cancer, prognosis, therapy and prevention strategies. Objectives: This project aims to identify angiogenic markers in head and neck cancer (CCP), thyroid cancer (CT) and hepatocellular carcinoma (HCC)…
(Only some records are available in English at this moment)
Among the reported cases of head and neck cancer, Head and Neck Squamous Cell Carcinoma (HNSCC) is responsible for approximately 90%, being a disease with a high mortality rate and poor prognosis. Oral Squamous Cell Carcinoma (OSCC), usually diagnosed at an advanced stage, has a high frequency of recurrence and metastasis and a 5-year survival rate of about 50%. Morbidity and mortality as…
Hepatocellular Carcinoma (HCC) is the most frequent primary liver cancer, accounting for 90% of liver-initiated liver cancers, and for 70-80% of all liver cancers. With a very high death rate, liver cancer ranks fourth in cancer-related deaths. Peroxisome proliferator-activated receptors (PPARs) belong to a family of ligand-activated nuclear receptors that act as transcription factors, re…
Head and neck cancer (HNSCC) includes malignant tumors belonging to a heterogeneous class, affecting tissues located in the upper portion of the neck, such as the lip, oral cavity, nasal cavity, paranasal sinuses, larynx and pharynx, with the HNSCC being the sixth most common type of cancer in the world. Even with the development of targeted therapies, the death rate of this disease is st…
Head and neck cancer (CCP) is a heterogeneous class of tumors because it affects several regions such as the mouth, larynx, nasopharynx and thyroid, making it difficult to diagnose the disease early and prognosis. Even with advances in treatment the survival rate for this type of cancer is still low due to tumor recurrence and the formation of metastases. One explanation for these events …
(Only some records are available in English at this moment)
Background: Current evidence suggests that initiation, growth, and invasion of cancer are driven by cancer stem cells (CSC). Furthermore, chemotherapy treatment for head and neck cancer (HNC) has shown unfavorable results due to tumor resistance due to CSC. Objectives: To understand and follow all techniques about identification of head and neck cancer stem cells for development…
| 1 / 1 | Ongoing research grants |
| 33 / 15 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 31 / 15 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 67 / 33 | All research grants and scholarships |
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