CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's at Medicina from Universidade Federal de São Paulo (1976). Master's degree (1984) and PhD thesis (1985) at Gynecology and Obstetrics Department from Universidade Federal de São Paulo. Chairman of Gynecology Division of Obstetrics and Gynecology Department of Faculdade de Medicina da USP. Dean of Graduation of Medical School and Assistant Graduate Dean of the University of Sao Paulo. Chairman of the graduate committee of the School of Medicine, Research area: endocrine gynecology and reproductive health. Past Editor of the journal Clinics. CNPq Researcher (1A). (Source: Lattes Curriculum)
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Melatonin is an indolaminergic pineal hormone that plays an important role in the regulation of the cardiovascular, neurological, immune, integumentary, endocrine systems, in particular, metabolism and reproductive processes. In the reproductive system, it is known that melatonin participates in physiological processes from the release of GnRH in the hypothalamus to endometrial receptivit…
The estrogens are responsible for many biologic process in ovaries. Their production and secretion contribute significantly for maintenance of women physiology. The 17 ²-estradiol (E2) is the more active form of natural estrogen. To perform its biological functions depends on estrogen receptor activation (ER± ou ²). Additionally, E2 controls the PI3K/AKT signaling pathway due to increased…
In previous and pioneer studies, we showed that, upon injection in the blood circulation, non-protein lipid nanoemulsions (LDE) with composition resembling low-density lipoprotein (LDL) have the ability to carry chemotherapeutic agents and concentrate them in malignant tumors or inflammation sites. By using LDE as vehicle, toxicity of those drugs was pronouncedly reduced without loss of a…
Collaboration of Professor Ricardo Azziz in the development of research projects on polycystic ovaries and to bring academic and teaching novelties to the Faculty and current students of the Discipline of Gynecology from the Department of Obstetrics and Gynecology of the University of São Paulo School of Medicine. Description of Activities: Professor Ricardo Azziz will interact with Profe…
(Only some records are available in English at this moment)
MicroRNAs (miRNAs) are small non-coding RNAs that act in gene expression regulation. Abnormal expression is associated with cellular transformation, compromised therapeutic response, and worse prognosis in breast carcinoma due to regulatory effects on important signaling pathways. Nowadays, there is great interest in identifying modulating substances of miRNA expressions that might be use…
Estrogens account for numerous biological processes. In the ovaries, its production and secretion contribute significantly to the maintenance of female physiology. 17 ²-estradiol (E2) is the most active form of natural estrogen. To perform its function it depends on the activation of its receptor (ERa or b). In addition, it controls the PI3K / AKT signaling pathway by increasing its inter…
Polycystic Ovary Syndrome (PCOS) is a highly prevalent disorder in menacme women. There has been some improvement in the knowledge of this syndrome, but there are still some challenges in reproduction, mainly the low pregnancy rates and the obstetrical complications. It is thought that the endometrium would be responsible for those challenges. However only a bit is known about its transfo…
The temporomandibular dysfunction (TMD) comprises disorders in joint structures and/or muscles related to the temporomandibular joint (TMJ). Presents a high prevalence in females, suggesting a possible hormonal role, especially estrogens. Knowing that the hormonal action is dependent on the bindinghormone to its receptor, several studies have attempted to identify these components in temp…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 17 / 9 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 7 / 5 | Completed scholarships in Brazil |
| 26 / 16 | All research grants and scholarships |
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