Abstract
Gene profiling with the 21-gene panel known as Oncotype® is currently being routinely used for prognostic stratification of patients with hormone receptor-positive, HER2/neu-negative breast tumors, typically with negative axillary lymph nodes. For patients with a score above 25 in postmenopausal or 20 in premenopausal stages, Oncotype is used to indicate adjuvant chemotherapy. In addition…