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Sâmia Regiane Lourenço Joca

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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Bachelor's at Farmácia Bioquímia from Universidade Federal do Paraná (1999) and doctorate at Pharmacology from Universidade de São Paulo (2004). Has experience in Pharmacology, focusing on Psychopharmacology, acting on the following subjects: antidepressant, cannabinoids, nitric oxide, stress and neuroplasticity. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher
Research suggests cannabidiol can reduce symptoms of depression 
Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated February 22, 2020
Total / Available in English
Most frequent collaborators in research granted by FAPESP
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (16)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications15
Citations107
Cit./Article7.1
Data from Web of Science

SALES, AMANDA J.; FOGACA, MANOELA V.; SARTIM, ARIANDRA G.; PEREIRA, VITOR S.; WEGENER, GREGERS; GUIMARAES, FRANCISCO S.; JOCA, SAMIA R. L.. Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex. Molecular Neurobiology, v. 56, n. 2, p. 1070-1081, . Web of Science Citations: 17. (12/17626-7, 15/01955-0)

SALES, AMANDA J.; JOCA, SAMIA R. L.. Antidepressant administration modulates stress-induced DNA methylation and DNA methyltransferase expression in rat prefrontal cortex and hippocampus. Behavioural Brain Research, v. 343, p. 8-15, . Web of Science Citations: 2. (11/17281-7)

SCOPINHO, AMERICA A.; LISBOA, SABRINA F. S.; GUIMARAES, FRANCISCO S.; CORREA, FERNANDO M. A.; RESSTEL, LEONARDO B. M.; JOCA, SAMIA R. L.. Dorsal and Ventral Hippocampus Modulate Autonomic Responses but Not Behavioral Consequences Associated to Acute Restraint Stress in Rats. PLoS One, v. 8, n. 10, . Web of Science Citations: 13. (11/17281-7, 12/09300-4)

PEREIRA, VITOR S.; CASAROTTO, PLINIO C.; HIROAKI-SATO, VINICIUS A.; SARTIM, ARIANDRA G.; GUIMARAES, FRANCISCO S.; JOCA, SAMIA R. L.. Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: Involvement of nitric oxide. European Neuropsychopharmacology, v. 23, n. 12, p. 1769-1778, . Web of Science Citations: 25. (11/17281-7, 07/03685-3)

JOCA‚ S.R.L.; ZANELATI‚ T.; GUIMARÃES‚ F.S.. Post-stress facilitation of serotonergic‚ but not noradrenergic‚ neurotransmission in the dorsal hippocampus prevents learned helplessness development in rats. Brain Research, v. 1087, n. 1, p. 67-74, . (02/13197-2)

STANQUINI, LAURA A.; RESSTEL, LEONARDO B. M.; CORREA, FERNANDO M. A.; JOCA, SAMIA R. L.; SCOPINHO, AMERICA A.. Prelimbic cortex 5-HT1A and 5-HT2C receptors are involved in the hypophagic effects caused by fluoxetine in fasted rats. Pharmacology Biochemistry and Behavior, v. 136, p. 31-38, . Web of Science Citations: 3. (13/06569-5)

SALES, AMANDA JULIANA; LOURENCO JOCA, SAMIA REGIANE. Effects of DNA methylation inhibitors and conventional antidepressants on mice behaviour and brain DNA methylation levels. ACTA NEUROPSYCHIATRICA, v. 28, n. 1, p. 11-22, . Web of Science Citations: 16. (12/17626-7, 11/17281-7)

GODOY, LIVEA DORNELA; UMEOKA, EDUARDO H. L.; RIBEIRO, DEIDIANE ELISA; SANTOS, VICTOR RODRIGUES; ANTUNES-RODRIGUES, JOSE; LOURENCO JOCA, SAMIA REGIANE; GARCIA-CAIRASCO, NORBERTO. Multimodal early-life stress induces biological changes associated to psychopathologies. Hormones and Behavior, v. 100, p. 69-80, . Web of Science Citations: 3. (14/17959-1, 15/18773-1, 17/11339-0, 13/01737-7)

SARTIM, ARIANDRA G.; SALES, AMANDA J.; GUIMARAES, FRANCISCO S.; JOCA, SAMIA R. L.. Hippocampal mammalian target of rapamycin is implicated in stress-coping behavior induced by cannabidiol in the forced swim test. JOURNAL OF PSYCHOPHARMACOLOGY, v. 32, n. 8, p. 922-931, . Web of Science Citations: 3. (15/01955-0)

SALES, AMANDA J.; CRESTANI, CARLOS C.; GUIMARAES, FRANCISCO S.; JOCA, SAMIA R. L.. Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, v. 86, p. 255-261, . Web of Science Citations: 11. (15/01955-0)

DINIZ, CASSIANO R. A. F.; BIOJONE, CAROLINE; JOCA, SARNIA R. L.; RANTAMAKI, TOMI; CASTREN, EERO; GUIMARAES, FRANCISCO S.; CASAROTTO, PLINIO C.. Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors. PeerJ, v. 7, . Web of Science Citations: 0. (13/02549-0, 18/04250-5, 11/02746-4, 13/01029-2)

PEREIRA, VITOR SILVA; ELFVING, BETINA; JOCA, SAMIA R. L.; WEGENER, GREGERS. Ketamine and aminoguanidine differentially affect Bdnf and Mtor gene expression in the prefrontal cortex of adult male rats. European Journal of Pharmacology, v. 815, p. 304-311, . Web of Science Citations: 4. (13/00916-5)

SARTIM, A. G.; MOREIRA, F. A.; JOCA, S. R. L.. INVOLVEMENT OF CB1 AND TRPV1 RECEPTORS LOCATED IN THE VENTRAL MEDIAL PREFRONTAL CORTEX IN THE MODULATION OF STRESS COPING BEHAVIOR. Neuroscience, v. 340, p. 126-134, . Web of Science Citations: 9. (12/17626-7, 13/00279-5)

RIBEIRO, DEIDIANE E.; MUELLER, HEIDI K.; ELFVING, BETINA; ESKELUND, AMANDA; JOCA, SAMIA R. L.; WEGENER, GREGERS. Antidepressant-like effect induced by P2X7 receptor blockade in FSL rats is associated with BDNF signalling activation. JOURNAL OF PSYCHOPHARMACOLOGY, v. 33, n. 11, p. 1436-1446, . Web of Science Citations: 1. (13/01737-7)

RIBEIRO, DEIDIANE ELISA; CASAROTTO, PLINIO C.; STAQUINI, LAURA; PINTO E SILVA, MARIA AUGUSTA; BIOJONE, CAROLINE; WEGENER, GREGERS; JOCA, SAMIA. Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model. PeerJ, v. 7, . Web of Science Citations: 0. (13/01737-7)

WERNER, C. T.; MITRA, S.; MARTIN, J. A.; STEWART, A. F.; LEPACK, A. E.; RAMAKRISHNAN, A.; GOBIRA, P. H.; WANG, Z. -J.; NEVE, R. L.; GANCARZ, A. M.; et al. Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving. SCIENCE ADVANCES, v. 5, n. 10, . Web of Science Citations: 0. (17/19284-0)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SARTIM, Ariandra Guerini. Possível interação entre os sistemas endocanabinóide, glutamatérgico e nitrérgico do CPFmv na modulação de respostas emocionais/comportamentais ao estresse. 2017. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

MONTEZUMA, Karina. Efeito de antagonistas do receptor NMDA sobre a metilação do DNA. 2016. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

NAGAI, Michelly Martins. Participação do sistema noradrenérgico do núcleo leito da estria terminal na mediação das consequências comportamentais do estresse. 2012. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

SARTIM, Ariandra Guerini. Efeitos da administração de canabidiol no CPFmv de ratos submetidos ao teste do nado forçado. 2013. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

CANTELMO, Rebeca Araujo. Efeito de inibidores da metilação de DNA sobre a neurotoxicidade induzida por iodeto de 1-metil-4-fenilpiridínio (MPP+) em modelo de células neuroniais. 2017. Dissertação (Mestrado) - Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto.

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