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Flavio da Silva Emery

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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Pharmacist graduated from the Federal University of Rio de Janeiro (1998), I obtained the title of Doctor of Chemistry of Natural Products in 2005 by the same institution in the Nucleus of Natural Products Research (NPPN). I am currently an Associate Professor at the Faculty of Pharmaceutical Sciences of Ribeirão Preto at the University of São Paulo, developing research projects in the areas of medicinal chemistry and synthesis of heterocycles, exploring diverse targets for the discovery of new bioactive compounds in cancer, infectious diseases and CNS diseases, while expanding the chemical space towards innovation. I am the President of the Brazilian Association of Pharmaceutical Sciences (2019-2020), as well as an active member of the IUPAC Drug Discovery and Development Subcommittee. I also act as coordinator of the Post-Graduate Program in Pharmaceutical Sciences of Ribeirão Preto. During my career I have visited several Institutions as visiting Professor/Researcher at Rice University and the University of East Anglia. (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (33)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

REZENDE, LUCAS C. D.; EMERY, FLAVIO S.. Fluorescence Quenching of Two meso-Substituted Tetramethyl BODIPY Dyes by Fe(III) Cation. Journal of the Brazilian Chemical Society, v. 26, n. 5, p. 1048-1053, . Web of Science Citations: 3. (13/24408-9, 11/23342-9)

SANTOS, GABRIELA B.; ALMEIDA, MARILIA O.; CARDOSO, IARA A.; MANFRIM, VIVIANE; CHAGAS, FERNANDA O.; TOLEDO, JULIANO S.; PINZAN, CAMILA C.; DE ARAUJO, ALEXANDRE SUMAN; CRUZ, ANGELA K.; PUPO, MONICA T.; et al. The Semisynthetic Landscape of Aphidicolin: Inspiration Towards Leishmanicidal Compounds. Journal of the Brazilian Chemical Society, v. 25, n. 10, p. 1885+, . Web of Science Citations: 2. (09/14184-0, 09/51812-0)

PERES, RAPHAEL S.; SANTOS, GABRIELA B.; CECILIO, NERRY T.; JABOR, VALQURIA A. P.; NIEHUES, MICHAEL; TORRES, BRUNA G. S.; BUQUI, GABRIELA; SILVA, CARLOS H. T. P.; DALLA COSTA, TERESA; LOPES, NORBERTO P.; et al. Lapachol, a compound targeting pyrimidine metabolism, ameliorates experimental autoimmune arthritis. ARTHRITIS RESEARCH & THERAPY, v. 19, . Web of Science Citations: 5. (09/54014-7, 14/50265-3, 12/20990-2, 12/25075-0, 13/08216-2)

REZENDE, LUCAS C. D.; MELO, SHAIANI M. G.; BOODTS, STIJN; VERBELEN, BRAM; EMERY, FLAVIO S.; DEHAEN, WIM. Thiocyanation of 3-substituted and 3,5-disubstituted BODIPYs and its application for the synthesis of new fluorescent sensors. DYES AND PIGMENTS, v. 154, p. 155-163, . Web of Science Citations: 3. (14/18973-8, 11/23342-9, 14/22451-7)

SILVA JUNIOR, P. E.; REZENDE, L. C. D.; GIMENES, JULIA POSSAMAI; MALTAROLLO, VINICIUS GONCALVES; DALE, JAMES; TROSSINI, G. H. G.; EMERY, F. S.; GANESAN, A.. Synthesis of two `heteroaromatic rings of the future' for applications in medicinal chemistry. RSC ADVANCES, v. 6, n. 27, p. 22777-22780, . Web of Science Citations: 2. (12/20990-2, 11/23342-9, 13/26485-0)

CASTRO, FELIPE FREITAS; RUY, PATRICIA C.; ZEVIANI, KARMA NOGUEIRA; SANTOS, RAMON FREITAS; TOLEDO, JULIANO SIMOES; CRUZ, ANGELA KAYSEL. Evidence of putative non-coding RNAs from Leishmania untranslated regions. Molecular and Biochemical Parasitology, v. 214, p. 69-74, . Web of Science Citations: 1. (13/50219-9, 09/14184-0, 12/17025-3, 12/16749-8)

PAEZ GONZALEZ, MARIA TERESA; FUMAGALLI, FERNANDO; BENEVENUTO, CAROLINA GOMES; EMERY, FLAVIO DA SILVA; GASPAR, LORENA RIGO. Novel benzophenone-3 derivatives with promising potential as UV filters: Relationship between structure, photoprotective potential and phototoxicity. European Journal of Pharmaceutical Sciences, v. 101, p. 200-210, . Web of Science Citations: 3. (12/20990-2, 10/00086-4)

SANTOS, GABRIELA B.; KROGH, RENATA; MAGALHAES, LUMA G.; ANDRICOPULO, ADRIANO D.; PUPO, MONICA T.; EMERY, FLAVIO S.. Semisynthesis of new aphidicolin derivatives with high activity against Trypanosoma cruzi. Bioorganic & Medicinal Chemistry Letters, v. 26, n. 4, p. 1205-1208, . Web of Science Citations: 7. (09/14184-0, 13/07600-3)

FUMAGALLI, FERNANDO; EMERY, FLAVIO DA SILVA. Charting the Chemical Reactivity Space of 2,3-Substituted Furo[2,3-b]pyridines Synthesized via the Heterocyclization of Pyridine-N-oxide Derivatives. Journal of Organic Chemistry, v. 81, n. 21, p. 10339-10347, . Web of Science Citations: 10. (14/50265-3, 15/06588-5)

MALTAROLLO, VINICIUS G.; HONORIO, KATHIA M.; EMERY, FLAVIO S.; GANESAN, ARASU; TROSSINI, GUSTAVO H. G.. Hologram quantitative structure-activity relationship and comparative molecular interaction field analysis of aminothiazole and thiazolesulfonamide as reversible LSD1 inhibitors. Future Medicinal Chemistry, v. 7, n. 11, p. 1381-1394, . Web of Science Citations: 3. (12/20990-2)

VERBELEN, BRAM; DIAS REZENDE, LUCAS CUNHA; BOODTS, STIJN; JACOBS, JEROEN; VAN MEERVELT, LUC; HOFKENS, JOHAN; DEHAEN, WIM. Radical CH Alkylation of BODIPY Dyes Using Potassium Trifluoroborates or Boronic Acids. CHEMISTRY-A EUROPEAN JOURNAL, v. 21, n. 36, p. 12667-12675, . Web of Science Citations: 28. (13/24408-9)

PINHEIRO, MATHEUS PINTO; EMERY, FLAVIO DA SILVA; CRISTINA NONATO, M.. Target Sites for the Design of Anti-trypanosomatid Drugs Based on the Structure of Dihydroorotate Dehydrogenase. CURRENT PHARMACEUTICAL DESIGN, v. 19, n. 14, p. 2615-2627, . Web of Science Citations: 18. (09/14184-0, 07/08703-0)

DIAS DE REZENDE, LUCAS CUNHA; VAIDERGORN, MIGUEL MENEZES; BIAZZOTTO MORAES, JULIANA CRISTINA; EMERY, FLAVIO DA SILVA. Synthesis, Photophysical Properties and Solvatochromism of Meso-Substituted Tetramethyl BODIPY Dyes. Journal of Fluorescence, v. 24, n. 1, p. 257-266, . Web of Science Citations: 20. (11/23342-9)

TROSSINI, GUSTAVO H. G.; MALTAROLLO, VINICIUS G.; SCHMIDT, THOMAS J.. Hologram QSAR Studies of Antiprotozoal Activities of Sesquiterpene Lactones. Molecules, v. 19, n. 7, p. 10546-10562, . Web of Science Citations: 9. (11/11499-0, 13/50677-7)

DIAS DE REZENDE, LUCAS CUNHA; GIL DE MELO, SHAIANI MARIA; BOODTS, STIJN; VERBELEN, BRAM; DEHAEN, WIM; EMERY, FLAVIO DA SILVA. Thiocyanation of BODIPY dyes and their conversion to thioalkylated derivatives. ORGANIC & BIOMOLECULAR CHEMISTRY, v. 13, n. 21, p. 6031-6038, . Web of Science Citations: 5. (13/24408-9, 12/20990-2, 11/23342-9)

SILVA, G. N. S.; REZENDE, L. C. D.; EMERY, F. S.; GOSMANN, G.; GNOATTO, S. C. B.. Natural and Semi synthetic Antimalarial Compounds: Emphasis on the Terpene Class. MINI-REVIEWS IN MEDICINAL CHEMISTRY, v. 15, n. 10, p. 809-836, . Web of Science Citations: 5. (12/20990-2)

TROSSINI, GUSTAVO H. G.; MALTAROLLO, VINICIUS G.; GARCIA, RICARDO D'A.; PINTO, CLAUDINEIA A. S. O.; VELASCO, MARIA V. R.; HONORIO, KATHIA M.; BABY, ANDRE R.. Theoretical study of tautomers and photoisomers of avobenzone by DFT methods. Journal of Molecular Modeling, v. 21, n. 12, . Web of Science Citations: 8. (13/50677-7)

FERREIRA, SAMUEL R. A.; FRANCO, MARCIA S. F.; DINIZ, EVELYN M. L. P.; EMERY, FLAVIO DA SILVA; CLOSOSKI, GIULIANO CESAR. Drug Likeness and Selective Functionalization of Quinoxalines. CURRENT ORGANIC SYNTHESIS, v. 12, n. 6, p. 714-729, . Web of Science Citations: 5. (13/04766-8, 12/20990-2, 12/14362-9, 12/08589-0)

VESSECCHI, RICARDO; EMERY, FLAVIO S.; GALEMBECK, SERGIO E.; LOPES, NORBERTO P.. Fragmentation studies and electrospray ionization mass spectrometry of lapachol: protonated, deprotonated and cationized species. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, v. 24, n. 14, p. 2101-2108, . Web of Science Citations: 27. (09/08281-3, 05/01572-1, 09/14184-0)

FUMAGALLI, FERNANDO; EMERY, FLAVIO DA SILVA. Pd(II)-mediated cyclodehydrogenation of formyldiarylamines-total synthesis of natural carbazoles clauraila A, clausenal and 6-methoxymurrayanine. Tetrahedron Letters, v. 56, n. 18, p. 2307-2310, . Web of Science Citations: 9. (12/20990-2, 13/00727-8)

ANDRADE, MICASSIO F.; KABEYA, LUCIANA M.; AZZOLINI, ANA ELISA C. S.; SANTOS, EVERTON O. L.; FIGUEIREDO-RINHEL, ANDREA S. G.; PARIS, MARCIO R. P.; EMERY, FLAVIO S.; PUPO, MONICA T.; LUCISANO-VALIM, YARA M.. 3-Phenylcoumarin derivatives selectively modulate different steps of reactive oxygen species production by immune complex-stimulated human neutrophils. International Immunopharmacology, v. 15, n. 2, p. 387-394, . Web of Science Citations: 8. (09/14184-0, 07/00840-8, 07/02487-3)

DE TOLEDO, JULIANO S.; JUNIOR, PAULO E. S.; MANFRIM, VIVIANE; PINZAN, CAMILA F.; DE ARAUJO, ALEXANDRE S.; CRUZ, ANGELA K.; EMERY, FLAVIO S.. Synthesis, Cytotoxicity and In Vitro Antileishmanial Activity of Naphthothiazoles. CHEMICAL BIOLOGY & DRUG DESIGN, v. 81, n. 6, p. 749-756, . Web of Science Citations: 4. (09/14184-0, 09/51812-0)

FUMAGALLI, FERNANDO; WARRATZ, SVENJA; ZHANG, SHOU-KUN; ROGGE, TORBEN; ZHU, CUIJU; STUECKL, A. CLAUDIA; ACKERMANN, LUTZ. Arene-Ligand-Free Ruthenium(II/III) Manifold for meta-C-H Alkylation: Remote Purine Diversification. CHEMISTRY-A EUROPEAN JOURNAL, v. 24, n. 16, p. 3984-3988, . Web of Science Citations: 18. (16/24448-9)

SANTOS, GABRIELA B.; GANESAN, A.; EMERY, FLAVIO S.. Oral Administration of Peptide-Based Drugs: Beyond Lipinski's Rule. CHEMMEDCHEM, v. 11, n. 20, p. 2245-2251, . Web of Science Citations: 23. (12/20990-2)

FREIRE FRANCO, MARCIA SILVANA; DE PAULA, MURILO HELDER; GLOWACKA, PAULINA CECYLIA; FUMAGALLI, FERNANDO; CLOSOSKI, GIULIANO CESAR; EMERY, FLAVIO DA SILVA. Palladium-catalyzed C-H alkenylation of quinoxaline N-oxide enabled by a mono-N-protected amino acid. Tetrahedron Letters, v. 59, n. 26, p. 2562-2566, . Web of Science Citations: 1. (14/50265-3, 15/12811-9, 12/20990-2, 17/21146-4)

DIAS DE REZENDE, LUCAS CUNHA; FUMAGALLI, FERNANDO; BORTOLIN, MARRAIANA SCHIAVON; DE OLIVEIRA, MARIANNE GARCIA; DE PAULA, MURILO HELDER; DE ANDRADE-NETO, VALTER FERREIRA; EMERY, FLAVIO DA SILVA. In vivo antimalarial activity of novel 2-hydroxy-3-anilino-1,4-naphthoquinones obtained by epoxide ring-opening reaction. Bioorganic & Medicinal Chemistry Letters, v. 23, n. 16, p. 4583-4586, . Web of Science Citations: 17. (09/14184-0)

FUMAGALLI, FERNANDO; GIL DE MELO, SHAIANI MARIA; RIBEIRO, CAMILA MARINGOLO; SOLCIA, MARIANA CRISTINA; PAVAN, FERNANDO ROGERIO; EMERY, FLAVIO DA SILVA. Exploiting the furo [2,3-b]pyridine core against multidrug-resistant Mycobacterium tuberculosis. Bioorganic & Medicinal Chemistry Letters, v. 29, n. 8, p. 974-977, . Web of Science Citations: 0. (14/50265-3, 17/21146-4, 15/06588-5, 18/00163-0)

CALIL, FELIPE A.; DAVID, JULIANA S.; CHIAPPETTA, ESTELA R. C.; FUMAGALLI, FERNANDO; MELLO, RODRIGO B.; LEITE, FRANCO H. A.; CASTILHO, MARCELO S.; EMERY, FLAVIO S.; CRISTINA NONATO, M.. Ligand-based design, synthesis and biochemical evaluation of potent and selective inhibitors of Schistosoma mansoni dihydroorotate dehydrogenase. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 167, p. 357-366, . Web of Science Citations: 0. (15/25099-5, 17/21146-4, 15/06588-5)

MACHADO, LUANA A.; DE SOUZ, MARCOS C.; DA SILVA, CAROLINE M.; YONEDA, JULLIANE; DE REZENDE, LUCAS C. D.; EMERY, FLAVIO S.; DE SIMONE, CARLOS A.; DA SILVA JUNIOR, EUFRANIO N.; PEDROSA, LEANDRO F.. On the synthesis, optical and computational studies of novel BODIPY-based phosphoramidate fluorescent dyes. JOURNAL OF FLUORINE CHEMISTRY, v. 220, p. 9-15, . Web of Science Citations: 0. (11/23342-9)

SILVA, DANIEL GEDDER; EMERY, FLAVIO DA SILVA. Strategies towards expansion of chemical space of natural product-based compounds to enable drug discovery. Brazilian Journal of Pharmaceutical Sciences, v. 54, n. SI, . Web of Science Citations: 0. (14/50265-3, 17/21146-4, 17/22001-0)

DA SILVA JUNIOR, PAULO ELIANDRO; AMIN, HAWRAZ I. M.; NAUTH, ALEXANDER M.; EMERY, FLAVIO DA SILVA; PROTTI, STEFANO; OPATZ, TILL. Flow Photochemistry of Azosulfones: Application of ``Sunflow{''} Reactors. CHEMPHOTOCHEM, v. 2, n. 10, SI, p. 878-883, . Web of Science Citations: 4. (17/21146-4, 16/24817-4)

VAIDERGORN, MIGUEL M.; CARNEIRO, ZUMIRA A.; LOPES, CARLA D.; DE ALBUQUERQUE, SERGIO; REIS, FELIPE C. C.; NIKOLAOU, SOFIA; E MELLO, JULIANA F. R.; GENESI, GIOVANI L.; TROSSINI, GUSTAVO H. G.; GANESAN, A.; et al. beta-amino alcohols and their respective 2-phenyl-N-alkyl aziridines as potential DNA minor groove binders. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 157, p. 657-664, . Web of Science Citations: 1. (14/03812-9, 15/20302-7)

DA SILVA JUNIOR, EUFRANIO N.; DE MELO, ISADORA M. M.; DIOGO, EMILAY B. T.; COSTA, VERENICE A.; DE SOUZA FILHO, JOSE D.; VALENCA, WAGNER O.; CAMARA, CELSO A.; DE OLIVEIRA, RONALDO N.; DE ARAUJO, ALEXANDRE S.; EMERY, FLAVIO S.; et al. On the search for potential anti-Trypanosoma cruzi drugs: Synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 52, p. 304-312, . Web of Science Citations: 42. (09/14184-0, 09/51812-0)

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