graduate at Farmácia Bioquímica from Faculdades Oswaldo Cruz (2000) and ph.d. at Análises Clínicas from Faculdades de Ciências Farmacêuticas (2005). Has experience in Pharmacy (Source: Lattes Curriculum)
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Hematopoiesis occurs in the bone marrow (BM) in regions called microenvironments, which modulate the processes of differentiation, proliferation and self-renewal of the hematopoietic stem cell (HSC). In recent years, the literature has given attention to the role of cells that comprise and form these microenvironments, especially the mesenchymal stromal cell. Additionally, elderly people …
Hematopoiesis occurs in the bone marrow in regions named microenvironments, which modulate the processes of differentiation, proliferation and self-renewal of the hematopoietic stem cell (HSC). In recent years the literature has given attention to the role of medullary endothelial cells in the ability to modulate and sustain hematopoiesis associated with endothelial cells. The role of mes…
Increase in life expectancy has been associated with high risk of development of age-associated diseases. Anemia and endothelial dysfunction are a common finding in the elderly and can lead to serious conditions such as heart failure. The causes of anemia in the elderly are multifactorial and commonly associate to micronutrient and/or macronutrient insufficiency. Endothelial cells play im…
Malnutrition is considered a disease responsible for 55% of children deaths worldwide, mainly under five years old. The FAO (Food and Agriculture Organization) says that in 2012 there were about 86 million malnourished people worldwide and protein malnutrition (PM) is the most common. It is known that the PM causes hematological disorders such as anemia and histological changes in the bon…
(Only some records are available in English at this moment)
Hematopoietic tissue, such as tissues that have a high rate of cell turnover, require a broad source of nutrients and can be altered by deficient nutritional states. Protein malnutrition (PM) compromises lymphohematopoietic organs and modifies the immune response. Our work shows that malnutrition causes anemia and leukopenia. In addition to quantitative changes, we observed qualitative al…
Malnutrition is responsible for 55% of child deaths worldwide and is considered the most deadly disease for children under five years of age. The FAO (Food and Agriculture Organization) says that in 2012 there were about 86 million malnourished people worldwide. Protein-energy malnutrition (PEM) is the most prevalent form of malnutrition and is defined by the WHO (World Health Organizatio…
The development of an appropriate immune response is very important for the maintenance of homeostasis, a series of processes are triggered from the first contact with pathogenic microorganisms to the effectiveness of the immune memory response. For these processes occur properly, nutrients are necessary, including glutamine that plays roles as a substrate for energy supply, and nitrogen …
(Only some records are available in English at this moment)
Accidental and occupational exposure to ionizing radiation (IR) can induces cellular damage in many living organisms at sub-lethal doses. The energy deposited on the cells leads to the breakage of chemical bonds, damaging both basic structures and the DNA, resulting in a range of lesions in which DNA double strand breaks (DSB) have a pivotal role in determining whether cells survive radia…
Dietary restriction modify the innate and adaptive immune response, exerting effects on inflammatory and regulatory cytokine production also modifying the expression of genes directly involved in immune response. Macrophages and lymphocytes play key roles in innate and specific immune response and have high utilization rate of the amino acid glutamine, which is essential for energy and ni…
| 1 / 1 | Ongoing research grants |
| 8 / 5 | Completed research grants |
| 9 / 8 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 20 / 16 | All research grants and scholarships |
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CV Lattes
ORCID