Advanced search
Start date
Betweenand

Rita de Cassia Aleixo Tostes Passaglia

CV Lattes GoogleMyCitations ResearcherID ORCID


Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas de Ribeirão Preto (FCFRP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Holds a B.Sc. degree in Pharmacy - by the University of Sao Paulo, M.Sc. and Ph.D. (1996) in Biological Sciences (Pharmacology, FMRP) by the University of Sao Paulo. Held internships at the Albert Einstein College of Medicine, NY - USA, University of Montreal - Clinical Research Institute of Montreal - Canada and Augusta University (Medical College of Georgia), GA - USA. Professor and Chair of Pharmacology Department of the Ribeirao Preto Medical School (FMRP) - University of Sao Paulo, member of the Sao Paulo Research Foundation (FAPESP) and member of The Brazilian Academy of Sciences. Has experience in Cardiovascular Pharmacology and Physiology and interest directed to signaling pathways that control vascular function and its changes in arterial hypertension, diabetes and obesity. Specific Interests: glycosylation with N-acetilglucosamine (O-GlcNAc) and vascular (dys)function, involvement of cytokines, endothelins, aldosterone and sexual hormones in target-organ damage in cardiovascular diseases. (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated October 19, 2019
Total / Available in English
Most frequent collaborators in research granted by FAPESP
Contact researcher

Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.


 

 

 

 

Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (27)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications22
Citations246
Cit./Article11.2
Data from Web of Science

GIACHINI, F. R. C.; CARNEIRO, F. S.; LIMA, V. V.; CARNEIRO, Z. N.; BRANDS, M. W.; WEBB, R. C.; TOSTES, R. C.. A key role for Na+/K+-ATPase in the endothelium-dependent oscillatory activity of mouse small mesenteric arteries. Brazilian Journal of Medical and Biological Research, v. 42, n. 11, p. 1058-1067, . Web of Science Citations: 5. (06/01773-0)

GIACHINI, FERNANDA R. C.; ZEMSE, SAIPRASAD M.; CARNEIRO, FERNANDO S.; LIMA, VICTOR V.; CARNEIRO, ZIDONIA N.; CALLERA, GLAUCIA E.; ERGUL, ADVIYE; WEBB, R. CLINTON; TOSTES, RITA C.. Interleukin-10 attenuates vascular responses to endothelin-1 via effects on ERK1/2-dependent pathway. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, v. 296, n. 2, p. H489-H496, . Web of Science Citations: 17. (06/01773-0)

BRUDER-NASCIMENTO, T.; CHINNASAMY, P.; RIASCOS-BERNAL, D. F.; CAU, S. B.; CALLERA, G. E.; TOUYZ, R. M.; TOSTES, R. C.; SIBINGA, N. E. S.. Angiotensin II induces Fat1 expression/activation and vascular smooth muscle cell migration via Nox1-dependent reactive oxygen species generation. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, v. 66, p. 18-26, . Web of Science Citations: 35. (11/22035-5, 11/01785-6)

BECARI, CHRISTIANE; DURAND, MARINA T.; GUIMARAES, ALESSANDER O.; LATARO, RENATA M.; PRADO, CIBELE M.; DE OLIVEIRA, MAURO; CANDIDO, SARAI C. O.; PAIS, PALOMA; RIBEIRO, MAURICIO S.; BADER, MICHAEL; et al. Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice. FRONTIERS IN PHYSIOLOGY, v. 8, . Web of Science Citations: 2. (13/20549-7)

ALVES-LOPES, RHEURE; NEVES, KARLA B.; MONTEZANO, AUGUSTO C.; HARVEY, ADAM; CARNEIRO, FERNANDO S.; TOUYZ, RHIAN M.; TOSTES, RITA C.. Internal Pudental Artery Dysfunction in Diabetes Mellitus Is Mediated by NOX1-Derived ROS-, Nrf2-, and Rho Kinase-Dependent Mechanisms. Hypertension, v. 68, n. 4, p. 1056-1064, . Web of Science Citations: 10. (13/08216-2, 12/12178-6)

BRUDER-NASCIMENTO, THIAGO; DA SILVA, MARCONDES A. B.; TOSTES, RITA C.. The involvement of aldosterone on vascular insulin resistance: implications in obesity and type 2 diabetes. DIABETOLOGY & METABOLIC SYNDROME, v. 6, . Web of Science Citations: 15. (10/52214-6, 11/01785-6)

SILVA, MARCONDES A. B.; BRUDER-NASCIMENTO, THIAGO; CAU, STEFANY B. A.; LOPES, RHEURE A. M.; MESTRINER, FABIOLA L. A. C.; FAIS, RAFAEL S.; TOUYZ, RHIAN M.; TOSTES, RITA C.. Spironolactone treatment attenuates vascular dysfunction in type 2 diabetic mice by decreasing oxidative stress and restoring NO/GC signaling. FRONTIERS IN PHYSIOLOGY, v. 6, . Web of Science Citations: 12. (13/08216-2, 10/52214-6)

SILVA, MARCONDES ALVES B.; CAU, STEFANY BRUNO A.; LOPES, RHEURE ALVES M.; MANZATO, CARLA P.; NEVES, KARLA B.; BRUDER-NASCIMENTO, THIAGO; MESTRINER, FABIOLA LESLIE ANTUNES C.; MONTEZANO, AUGUSTO C.; CAT, AURELIE NGUYEN DINH; TOUYZ, RHIAN M.; et al. Mineralocorticoid receptor blockade prevents vascular remodelling in a rodent model of type 2 diabetes mellitus. Clinical Science, v. 129, n. 7, p. 533-545, . Web of Science Citations: 16. (10/52214-6)

BRUDER-NASCIMENTO, THIAGO; CALLERA, GLAUCIA E.; MONTEZANO, AUGUSTO C.; HE, YING; ANTUNES, TAYZE T.; CAT, AURELIE NGUYEN DINH; TOSTES, RITA C.; TOUYZ, RHIAN M.. Vascular injury in diabetic db/db mice is ameliorated by atorvastatin: role of Rac1/2-sensitive Nox-dependent pathways. Clinical Science, v. 128, n. 7, p. 411-423, . Web of Science Citations: 21. (10/52214-6, 11/22035-5, 11/01785-6)

LOPES, RHEURE A.; NEVES, KARLA B.; TOSTES, RITA C.; MONTEZANO, AUGUSTO C.; TOUYZ, RHIAN M.. Downregulation of Nuclear Factor Erythroid 2-Related Factor and Associated Antioxidant Genes Contributes to Redox-Sensitive Vascular Dysfunction in Hypertension. Hypertension, v. 66, n. 6, p. 1240-1250, . Web of Science Citations: 45. (12/12178-6)

BECARI, CHRISTIANE; SILVA, MARCONDES A. B.; DURAND, MARINA T.; PRADO, CIBELE M.; OLIVEIRA, EDUARDO B.; RIBEIRO, MAURICIO S.; SALGADO, HELIO C.; SALGADO, MARIA CRISTINA O.; TOSTES, RITA C.. Elastase-2, an angiotensin II-generating enzyme, contributes to increased angiotensin II in resistance arteries of mice with myocardial infarction. British Journal of Pharmacology, v. 174, n. 10, SI, p. 1104-1115, . Web of Science Citations: 2. (13/08216-2)

LIMA, VICTOR V.; GIACHINI, FERNANDA R.; MATSUMOTO, TAKAYUKI; LI, WEIGUO; BRESSAN, ALECSANDER F. M.; CHAWLA, DHRUV; WEBB, R. CLINTON; ERGUL, ADVIYE; TOSTES, RITA C.. High-fat diet increases O-GlcNAc levels in cerebral arteries: a link to vascular dysfunction associated with hyperlipidaemia/obesity?. Clinical Science, v. 130, n. 11, p. 871-880, . Web of Science Citations: 13. (13/08216-2)

NONATO, ARTHUR OLIVEIRA; OLIVON, VANIA C.; DELA JUSTINA, VANESSA; ZANOTTO, CAMILA Z.; CLINTON WEBB, R.; TOSTES, RITA C.; LIMA, VICTOR V.; GIACHINI, FERNANDA R.. Impaired Ca2+ Homeostasis and Decreased Orai1 Expression Modulates Arterial Hyporeactivity to Vasoconstrictors During Endotoxemia. Inflammation, v. 39, n. 3, p. 1188-1197, . Web of Science Citations: 2. (10/52214-6)

LIMA, VICTOR V.; ZEMSE, SAIPRASAD M.; CHIAO, CHIN-WEI; BOMFIM, GISELE F.; TOSTES, RITA C.; WEBB, R. CLINTON; GIACHINI, FERNANDA R.. Interleukin-10 limits increased blood pressure and vascular RhoA/Rho-kinase signaling in angiotensin II-infused mice. Life Sciences, v. 145, p. 137-143, . Web of Science Citations: 15. (10/52214-6)

BRUDER-NASCIMENTO, THIAGO; CALLERA, GLAUCIA; MONTEZANO, AUGUSTO CESAR; ANTUNES, TAYZE T.; HE, YING; CAT, AURELIE NGUYEN DINH; FERREIRA, NATHANNE S.; BARRETO, PEDRO A.; OLIVON, VANIA C.; TOSTES, RITA C.; et al. Renoprotective Effects of Atorvastatin in Diabetic Mice: Downregulation of RhoA and Upregulation of Akt/GSK3. PLoS One, v. 11, n. 9, . Web of Science Citations: 5. (11/22035-5, 11/01785-6)

GIACHINI, FERNANDA R. C.; LIMA, VICTOR V.; FILGUEIRA, FERNANDO P.; DORRANCE, ANNE M.; CARVALHO, MARIA HELENA C.; FORTES, ZULEICA B.; WEBB, R. CLINTON; TOSTES, RITA C.. STIM 1/Orai 1 contributes to sex differences in vascular responses to calcium in spontaneously hypertensive rats. Clinical Science, v. 122, n. 5-6, p. 215-226, . Web of Science Citations: 15. (09/08095-5)

SOUZA-SILVA, LEONARDO; ALVES-LOPES, RHEURE; MIGUEZ, JESSICA SILVA; DELA JUSTINA, VANESSA; NEVES, KARLA BIANCA; MESTRINER, FABIOLA LESLIE; TOSTES, RITA DE CASSIA; GIACHINI, FERNANDA REGINA; LIMA, VICTOR VITORINO. Glycosylation with O-linked beta-N-acetylglucosamine induces vascular dysfunction via production of superoxide anion/reactive oxygen species. Canadian Journal of Physiology and Pharmacology, v. 96, n. 3, . Web of Science Citations: 0. (13/08216-2)

MONTEZANO, AUGUSTO C.; AMIRI, FARHAD; TOSTES, RITA C.; TOUYZ, RHIAN M.; SCHIFFRIN, ERNESTO L.. Inhibitory effects of PPAR-gamma on endothelin-1-induced inflammatory pathways in vascular smooth muscle cells from normotensive and hypertensive rats. JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, v. 1, n. 2, p. 150-160, . Web of Science Citations: 15.

CALLERA, GLAUCIA E.; MONTEZANO, AUGUSTO C.; TOUYZ, RHIAN M.; ZORN, TELMA M. T.; CARVALHO, MARIA HELENA C.; FORTES, ZULEICA B.; NIGRO, DOROTHY; SCHIFFRIN, ERNESTO L.; TOSTES, RITA C.. ETA receptor mediates altered leukocyte-endothelial cell interaction and adhesion molecules expression in DOCA-salt rats. Hypertension, v. 43, n. 4, p. 872-879, .

BRUDER-NASCIMENTO, THIAGO; CALLERA, GLAUCIA E.; MONTEZANO, AUGUSTO C.; DE CHANTEMELE, ERIC J. BELIN; TOSTES, RITA C.; TOUYZ, RHIAN M.. Atorvastatin inhibits pro-inflammatory actions of aldosterone in vascular smooth muscle cells by reducing oxidative stress. Life Sciences, v. 221, p. 29-34, . Web of Science Citations: 0. (10/52214-6, 11/22035-5, 11/01785-6)

WYNNE, BRANDI M.; LABAZI, HICHAM; LIMA, VICTOR V.; CARNEIRO, FERNANDO S.; WEBB, R. CLINTON; TOSTES, RITA C.; GIACHINI, FERNANDA R.. Mesenteric arteries from stroke-prone spontaneously hypertensive rats exhibit an increase in nitric-oxide-dependent vasorelaxation. Canadian Journal of Physiology and Pharmacology, v. 96, n. 8, p. 719-727, . Web of Science Citations: 1. (10/52214-6)

BRESSAN, ALECSANDER F.; FONSECA, GISELE A.; TOSTES, RITA C.; WEBB, R. CLINTON; LIMA, VICTOR VITORINO; GIACHINI, FERNANDA REGINA. Interleukin-10 negatively modulates extracellular signal-regulated kinases 1 and 2 in aorta from hypertensive mouse induced by angiotensin II infusion. FUNDAMENTAL & CLINICAL PHARMACOLOGY, v. 33, n. 1, p. 31-40, . Web of Science Citations: 0. (10/52214-6)

R.C. TOSTES; D. NIGRO; Z.B. FORTES; M.H.C. CARVALHO. Effects of estrogen on the vascular system. Brazilian Journal of Medical and Biological Research, v. 36, n. 9, p. 1143-1158, .

POTJE, SIMONE R.; GRANDO, MARCELLA D.; CHIGNALIA, ANDREIA Z.; ANTONIALI, CRISTINA; BENDHACK, LUSIANE M.. Reduced caveolae density in arteries of SHR contributes to endothelial dysfunction and ROS production. SCIENTIFIC REPORTS, v. 9, . Web of Science Citations: 0. (17/14797-9, 16/22180-9, 16/21239-0)

CALLERA‚ G.E.; TOUYZ‚ R.M.; TEIXEIRA‚ S.A.; MUSCARA‚ M.N.; CARVALHO‚ M.H.C.; FORTES‚ Z.B.; NIGRO‚ D.; SCHIFFRIN‚ E.L.; TOSTES‚ R.C.. ETA receptor blockade decreases vascular superoxide generation in DOCA-salt hypertension. Hypertension, v. 42, n. 4, p. 811-817, .

MONTEZANO‚ ACI; CALLERA‚ GE; MOTA‚ AL; FORTES‚ ZB; NIGRO‚ D.; CARVALHO‚ MHC; ZORN‚ TMT; TOSTES‚ RC. Endothelin-1 contributes to the sexual differences in renal damage in DOCA-salt rats. Peptides, v. 26, n. 8, p. 1454-1462, .

CALLERA‚ G.; TOSTES‚ R.; YOGI‚ A.; MONTEZANO‚ A.; TOUYZ‚ R.. Endothelin-1-induced oxidative stress in DOCA-salt hypertension involves NADPH-oxidase-independent mechanisms. Clinical Science, v. 110, p. 243-253, .

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

YOGI, Alvaro. Mecanismos de regulação e função celular do magnésio na hipertensão induzida pela Aldosterona em um modelo genético de hipomagnesemia: papel dos canais TRPM7.. 2009. Tese (Doutorado) – Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (05/50558-1)

VITORINO, Fernanda Regina Casagrande Giachini. Contribuição da via STIM1/Orai1 para as diferenças relacionadas ao sexo na entrada de cálcio em miócitos vasculares durante a hipertensão arterial.. 2010. Tese (Doutorado) – Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (06/51398-0)

CARNEIRO, Fernando Silva. Papel do fator de necrose tumoral (TNF-a) na fisiopatologia da disfunção erétil.. 2011. Tese (Doutorado) – Instituto de Ciências Biomédicas. Universidade de São Paulo (USP). São Paulo. (06/51397-4)

PEREIRA, Camila André. Papel do inflamassoma NLRP3 nas alterações vasculares promovidas pelo diabetes tipo 1 em modelo induzido por estreptozotocina. 2018. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (16/17303-4)

FERREIRA, Pedro Afonso Barreto. O envolvimento de Receptores de Hidrocarbonetos de Arila (AhR) no desenvolvimento de lesões ateroscleróticas com fenótipo vulnerável em camundongos nocautes para apoliproteína E. 2018. Dissertação (Mestrado) - Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (15/11742-3)

COSTA, Rafael Menezes da. Contribuição da interleucina 33 nas alterações vasculares mediadas pelo tecido adiposo perivascular em camundongos submetidos à dieta hiperlipídica. 2018. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (16/14078-0)

Distribution map of accesses to this page
Click here to view the access summary to this page.
Please report errors in researcher information by writing to: cdi@fapesp.br.
X

Report errors in this page


Error details: