graduate at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1994), master's at Physiology from Universidade de São Paulo (1997) and ph.d. at Physiology from Universidade de São Paulo (2001). Has experience in Odontology, focusing on Bucomaxilofacial Surgery, acting on the following subjects: nts, nmda, ampa, imunocitoquímica and reparo alveolar. (Source: Lattes Curriculum)
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This project has the principal aim on evaluation of strategies that are related to the installation device (implants) that allow the improvement of repair bone in the presence of systemic condition, in pre-clinical, in vivo studies. The systemic impairment condition that will be focused on this study are osteoporosis, developed in ovariectomized rats and type 2 diabetes, developed in male…
The search for strategies that may improve the quality of bone formed around implants has involved techniques since the sophisticated design of the scrulls until the coating and treatment of their surface, in order to stimulate the activity of cells and the participation of signaling pathways that may activate responses that, in equilibrated manner, may produce bone with quality and quant…
This study will investigate the action of the association between systemic medication (oral bisphosphonate) an several medicines that will be locally applied in the surface of implants that will be installed in rat' maxilla. The medicines that will be used this study in order to functionalism the implant's surface will be Terpy (nitric oxide donator), teriparatide and genisteine. This pr…
Osteoporosis is the most common bone tissue metabolic disorder in women in the postmenopausal period, caused by estrogen deficiency. Also affects men, but in a lower incidence and usually occurs by reducing the production of testosterone, which suffer the flavoring process into estrogen. In order to understand the alveolar bone and the bone around dental implants healing behavior , thi…
(Only some records are available in English at this moment)
This project will investigate the local action of DNA hydrogels, functionalized or not with biomolecules, in bone reconstructions from models of critical defect in rat calvaria. For this, 246 young adult male Wistar rats will be used. 36 rats will be destined to the analysis of biocompatibility through the insertion of biomaterials in the subcutaneous tissue of the animals. The experiment…
The search for the ideal bone substitute has driven great advances in the field of Biomaterials in Dentistry. With the emergence of biomaterials that satisfactorily perform their osteoconductive role, we see the need to seek a biological improvement of these products, through the addition of biomolecules that can have a positive effect on reparative events, improving their properties. The…
(Only some records are available in English at this moment)
This study aims to investigate the local action of Rubus coreanus through the functionalization of the surface of the implant to be installed in the tibiae of female rats with estrogen deficiency. Forty-eight young adult female Wistar rats will be used. The experimental groups will be SHAM CONV, SHAM RC 200, SHAM RC 400, OVX CONV, OVX RC 200, AND OVX RC 400. The OVX animals will be submit…
Osteoporosis is a disease that mainly affects postmenopausal women. Currently, there are many therapies available for its treatment, including oral bisphosphonates, which are drugs with an anti-bone remodeling effect, which may lead to some adverse effects in the long term. Other therapeutic or adjuvant options have been considered in order to improve anti-osteoporosis therapies, among th…
(Only some records are available in English at this moment)
The aim of this study is to evaluate the peri-implant bone healing process by histomorphometric analysis and investigate the influences that losartan treatment may lead to peri-implant bone healing. The influence of losartan in the peri-implant bone healing will be investigated in 32 tibias of male rats; tibias was collected from 16 spontaneously hypertensive rats (SHR) and 48 normotensiv…
| 1 / 1 | Ongoing research grants |
| 6 / 6 | Completed research grants |
| 7 / 7 | Ongoing scholarships in Brazil |
| 44 / 39 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 59 / 54 | All research grants and scholarships |
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CV Lattes
ORCID