CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Faculdade de Odontologia (FOA) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Universidade de Passo Fundo (1985), master's at Physiology from Universidade de São Paulo (1993) and doctorate at Physiology from Universidade de São Paulo (1997). Has experience in Physiology, focusing on Endocrinal Physiology, acting on the following subjects: estradiol, metabolismo ósseo, ovariectomia, bone and exodontia. (Source: Lattes Curriculum)
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The objective of this study is to identify whether oxytocin (ot) contributes to the reduction of osteopenia in the femoral neck of rats in periestropause. Animals in irregular estrous cycles received two NaCl injections (0.15 mol/L) or OT (134 ¼g/kg) over a 12-h interval, and after thirty-five days without treatments, the biological sample collection was performed. the oxytocin group (ot)…
Aging is the result of cumulative, progressive, intrinsic, and deleterious functional and structural changes that usually begin to manifest in reproductive maturity, although their genesis may have been earlier. The reproductive function in female organisms is controlled by both the hypothalamic-pituitary-gonadal axis and the biological clock, both of which are fundamental for the outgrow…
The process of reproductive senescence in many female mammals, including humans, is characterized by gradual transition from regular reproductive cycles to irregular cycles (i.e., acyclicity), and ultimately to loss of fertility. The period of transition to acyclicity neuroendocrine has not been fully characterized and represents a complex interplay of actions at all levels of the hypotha…
(Only some records are available in English at this moment)
Changes in the plasma secretion of gonadal steroids that characterize stages of the female life cycle also interfere with the bone structure of these organisms, altering the process of bone remodeling and repair. The imbalance in bone microarchitecture results in osteopenia and osteoporosis, whose decrease in bone mass makes the bone structure fragile and susceptible to fracture. The fail…
The life stages of human beings are marked by cycles understood as childhood, adolescence, adulthood and old age. Functional capacity and homeostatic control mechanisms act and provide interaction with the environment, with characteristics specific to each cycle. The transition from adulthood to old age in women is marked by hormonal changes that trigger and enhance reproductive senescenc…
In women, deficiency of the reproductive hormone during menopause leads to an imbalance between resorption and bone formation, contributing to the decrease in tissue quality and favoring the incidence of osteoporosis and fractures. However, the reduction in bone quality and mass in the skeletal sites of the elderly person can result in delay or not consolidate the fracture. In addition, t…
(Only some records are available in English at this moment)
During female senescence, hypothalamic-pituitary-gonads display progressive reduction in their functions resulting in endocrine deficiency. Plasma concentrations of estrogen (E2) influence the mechanisms responsible for the maintenance of muscle mass, possibly through direct action of the E2. The hormone replacement therapy (HRT) has a protective effect on the maintenance of lean body mas…
| 6 / 5 | Completed research grants |
| 26 / 17 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 33 / 23 | All research grants and scholarships |
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