CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araçatuba. Faculdade de Odontologia (FOA) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Ciências Biológicas from Universidade de Passo Fundo (1985), master's at Physiology from Universidade de São Paulo (1993) and doctorate at Physiology from Universidade de São Paulo (1997). Has experience in Physiology, focusing on Endocrinal Physiology, acting on the following subjects: estradiol, metabolismo ósseo, ovariectomia, bone and exodontia. (Source: Lattes Curriculum)
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The objective of this study is to identify whether oxytocin (ot) contributes to the reduction of osteopenia in the femoral neck of rats in periestropause. Animals in irregular estrous cycles received two NaCl injections (0.15 mol/L) or OT (134 ¼g/kg) over a 12-h interval, and after thirty-five days without treatments, the biological sample collection was performed. the oxytocin group (ot)…
Aging is the result of cumulative, progressive, intrinsic, and deleterious functional and structural changes that usually begin to manifest in reproductive maturity, although their genesis may have been earlier. The reproductive function in female organisms is controlled by both the hypothalamic-pituitary-gonadal axis and the biological clock, both of which are fundamental for the outgrow…
The process of reproductive senescence in many female mammals, including humans, is characterized by gradual transition from regular reproductive cycles to irregular cycles (i.e., acyclicity), and ultimately to loss of fertility. The period of transition to acyclicity neuroendocrine has not been fully characterized and represents a complex interplay of actions at all levels of the hypotha…
(Only some records are available in English at this moment)
The life stages of human beings are marked by cycles understood as childhood, adolescence, adulthood and old age. Functional capacity and homeostatic control mechanisms act and provide interaction with the environment, with characteristics specific to each cycle. The transition from adulthood to old age in women is marked by hormonal changes that trigger and enhance reproductive senescenc…
In women, deficiency of the reproductive hormone during menopause leads to an imbalance between resorption and bone formation, contributing to the decrease in tissue quality and favoring the incidence of osteoporosis and fractures. However, the reduction in bone quality and mass in the skeletal sites of the elderly person can result in delay or not consolidate the fracture. In addition, t…
Aging is caused by cellular and molecular damage that results in progressive disability of some functions. Bone tissue, especially in postmenopausal women, can be greatly affected by osteopenia and the installation of osteoporosis. Studies have shown the effectiveness of aerobic exercise, strength and Concurrent Training in maintaining bone health and preventing bone loss. Objective: The …
The aging in the female organism is marked by the smallest estrogen plasmatic concentration, risk factor thoroughly recognized for osteoporosis. Another factor that is involved in the hormonal alterations happened in the menopause and in the physiopathology of the primary osteoporosis is the oxidative stress. Therapeutic proposal that contributes to improvement of the oxidative profile an…
The incidence of osteoporosis (OP), according to the literature, is higher in females in the menopausal period, related to deficiency of the gonadal steroid, a fundamental hormone in the activity of bone remodeling, which contributes to bone growth and peak bone mass. Among the new therapies, oxytocin (OT) has been investigated for its anabolic effects on bone tissue. Objective: The objec…
(Only some records are available in English at this moment)
During female senescence, hypothalamic-pituitary-gonads display progressive reduction in their functions resulting in endocrine deficiency. Plasma concentrations of estrogen (E2) influence the mechanisms responsible for the maintenance of muscle mass, possibly through direct action of the E2. The hormone replacement therapy (HRT) has a protective effect on the maintenance of lean body mas…
| 1 / 0 | Ongoing research grants |
| 5 / 5 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 23 / 14 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 32 / 22 | All research grants and scholarships |
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(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 7 |
| Citations | 14 |
| Cit./Article | 2.0 |
| Data from Web of Science | |
NICOLA, ANGELA CRISTINA; LEITE, CRISTIANE MOTA; BATISTA NISHIKAVA, MARIANE MAYUMI; BEDRAN DE CASTRO, JOAO CESAR; ANSELMO-FRANCI, JANETE APARECIDA; MENEGATI DORNELLES, RITA CASSIA. The transition to reproductive senescence is characterized by increase in A6 and AVPV neuron activity with attenuation of noradrenaline content. Experimental Gerontology, v. 81, p. 19-27, AUG 2016. Web of Science Citations: 3. (12/14464-6)
FERNANDES, FERNANDA; STRINGHETTA-GARCIA, CAMILA TAMI; PERES-UENO, MELISE JACON; FERNANDES, FABIANA; DE NICOLA, ANGELA CRISTINA; CASTOLDI, ROBSON CHACON; OZAKI, GUILHERME; QUIRINO LOUZADA, MARIO JEFFERSON; CHAVES-NETO, ANTONIO HERNANDES; ERVOLINO, EDILSON; et al. Oxytocin and bone quality in the femoral neck of rats in periestropause. SCIENTIFIC REPORTS, v. 10, n. 1, MAY 13 2020. Web of Science Citations: 0. (10/09393-7, 13/14262-7, 13/26779-4, 12/14464-6)
LOURENCO MORAIS, SAMUEL RODRIGUES; GOYA, ALEXANDRE GINEI; URIAS, URSULA; JANNIG, PAULO ROBERTO; NOVA BACURAU, ALINE VILLA; MELLO, WAGNER GARCEZ; FALEIROS, PAULA LAZILHA; PENHA OLIVEIRA, SANDRA HELENA; GARCIA, VALDIR GOUVEIA; ERVOLINO, EDILSON; et al. Strength training prior to muscle injury potentiates low-level laser therapy (LLLT)-induced muscle regeneration. Lasers in Medical Science, v. 32, n. 2, p. 317-325, FEB 2017. Web of Science Citations: 5. (13/18907-2)
NICOLA, ANGELA CRISTINA; FERREIRA, LARISSA BRAZOLOTO; MATA, MILENE MANTOVANI; VILHENA-FRANCO, TATIANE; LEITE, CRISTIANE MOTA; MARTINS, ANDRESSA BUSETTI; ANTUNES-RODRIGUES, JOSE; POLETINI, MARISTELA OLIVEIRA; MENEGATI DORNELLES, RITA CASSIA. Vasopressinergic Activity of the Suprachiasmatic Nucleus and mRNA Expression of Clock Genes in the Hypothalamus-Pituitary-Gonadal Axis in Female Aging. FRONTIERS IN ENDOCRINOLOGY, v. 12, AUG 24 2021. Web of Science Citations: 0. (12/14464-6)
SANTOS, LEANDRO FIGUEIREDO; SINGULANI, MONIQUE PATRICIO; STRINGHETTA-GARCIA, CAMILA TAMI; PENHA OLIVEIRA, SANDRA HELENA; CHAVES-NETO, ANTONIO HERNANDES; MENEGATI DORNELLES, RITA CASSIA. Oxytocin effects on osteoblastic differentiation of Bone Marrow Mesenchymal Stem Cells from adult and aging female Wistar rats. Experimental Gerontology, v. 113, p. 58-63, NOV 2018. Web of Science Citations: 2. (11/15501-0)
STRINGHETTA-GARCIA, CAMILA TAMI; LOURENCO MORAIS, SAMUEL RODRIGUES; FERNANDES, FERNANDA; PEREZ-UENO, MELISE JACON; ALMEIDA, RICARDO DE PAULA; QUIRINO LOUZADA, MARIO JEFFERSON; CHAVES-NETO, ANTONIO HERNANDES; ERVOLINO, EDILSON; MENEGATI DORNELLES, RITA CASSIA. Effects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats. SCIENTIFIC REPORTS, v. 7, OCT 31 2017. Web of Science Citations: 0. (13/18907-2)
FERREIRA, LARISSA BRAZOLOTTO; DE NICOLA, ANGELA CRISTINA; ANSELMO-FRANCI, JANETE APARECIDA; MENEGATI DORNELLES, RITA CASSIA. Activity of neurons in the preoptic area and their participation in reproductive senescence: Preliminary findings. Experimental Gerontology, v. 72, p. 157-161, DEC 2015. Web of Science Citations: 4. (12/14464-6)
(References retrieved automatically from State of São Paulo Research Institutions)
SANTOS, Leandro Figueiredo dos. Atuação da ocitocina no processo de diferenciação osteoblástica de ratas senis. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Faculdade de Odontologia (Campus de Araçatuba). (11/15501-0)
MORAIS, Samuel Rodrigues Lourenço de. Influência da terapêutica hormonal estrogênica e do treinamento de força sobre o tecido muscular esquelético de ratas senis. 88 f. Tese (Doutorado) - Universidade Estadual Paulista (Unesp) Faculdade de Odontologia. (13/18907-2)