CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biomédicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1999), master's at General Biology from Universidade Estadual de Campinas (2002) and doctorate at General Biology from Universidade Estadual de Campinas (2006). He is currently full professor at Universidade Estadual Paulista Júlio de Mesquita Filho. Has experience in Morphology, focusing on Embryology, acting on the following subjects: histologia, próstata, sistema reprodutor masculino, camundongo and pele. (Source: Lattes Curriculum)
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The incidence of chronic diseases such as diabetes and obesity, as well as genetic diseases such as cancer, has increased in recent decades due to several socio-economic and environmental factors. Thus, interest in environmental factors that interfere without intra-uterine development and rnorphofunctional, genetic and epigenetic promovamzy, including how they can be transmitted to offspr…
The incidence of chronic diseases such as diabetes and obesity, as well as genetic diseases such as cancer, has increased in recent decades due to several socioeconomic and environmental factors that seem to interfere in the development, incidence and prognosis of these diseases. With regard to cancer, the temporal factor distances in up to 50-60 years the stages of initiation and tumor p…
Prostate cancer is related to the endocrine system and its progression involves changes in estrogen and androgen signaling pathways. Therefore the investigation of drugs that interfere in these pathways creates perspective for discovery of novel therapeutic targets.In this scenario, androgen deprivation has been used as the main treatment for tumor reduction.The antiandrogen abiraterone a…
(Only some records are available in English at this moment)
The prostate gland is extremely important for the male reproductive system and is increasingly gaining prominence due to the high incidence of Prostate Cancer (PCa). Phthalates are a group of chemical compounds used as plasticizers to confer greater malleability and flexibility and are considered Endocrine Disruptors (ED) due to their antiandrogenic action. Previous work from our research…
The adrenal glands are highly active and responsible for producing hormones that maintain homeostasis, control blood pressure and stress responses, and thus influence metabolism and growth. When these glands are early exposed to stressful factors, such as environmental toxins, they can trigger important responses that result in alterations in their development and functionality. Currently…
Environmental factors have influenced the intrauterine microenvironment, which has had important consequences on late development due to the actuation of these substances as endocrine disruptors. It should be noticed that most of these substances are commonly found in food packaging materials, children's toys, nail polishes, special care products. Phthalates represent a group of ubiquitou…
The intrauterine microenvironment has been significantly altered due to the interference of environmental and/or socioeconomic factors, which can generate late and transgenerational consequences. Phthalates represent a class of molecules detected in different concentrations in breast milk, urine of pregnant women, amniotic fluid and human and rodents placenta. Previous studies have shown …
Infertility affects 10-15% of couples on reproductive age and male factor may be responsible for 30-50% of cases. Studies suggest that 60-70% male infertility cases are considered idiophatic, once the molecular mechanisms involved in spermatogenesis are still unknown. Male fertility and spermatogenesis process are directly related to the ability of Sertoli cells to produce factors for ger…
(Only some records are available in English at this moment)
Phthalates represent a class of molecules detected in different concentrations in breast milk, in the urine of pregnant women, and in the human and rodent placenta. Previous studies have shown that perinatal exposure to isolated phthalates increased susceptibility to prostatic carcinogenesis. Thus, the study seeks to investigate the OMICS profile on ventral prostate (VP) of senescent rats…
The incidence of chronic diseases such as diabetes and obesity, as well as genetic diseases such as cancer, has increased in recent decades due to several socioeconomic and environmental factors that seem to interfere in the development, incidence and prognosis of these diseases. Regarding cancer, the temporal factor distances up to 50-60 years the stages of initiation and tumor progressi…
Male fertility and spermatogenesis process are directly related to the ability of Sertoli cells to produce factors associated with germ cells development. Only the Sertoli cells have receptors for FSH and testosterone, and therefore these cells are the major spermatogenesis regulators. Studies suggest that 60-70% male infertility cases are considered idiophatic, since the molecular mechan…
| 6 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 20 / 17 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 2 / 2 | Completed scholarships abroad |
| 31 / 28 | All research grants and scholarships |
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