CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Ciências Biomédicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1999), master's at General Biology from Universidade Estadual de Campinas (2002) and doctorate at General Biology from Universidade Estadual de Campinas (2006). He is currently full professor at Universidade Estadual Paulista Júlio de Mesquita Filho. Has experience in Morphology, focusing on Embryology, acting on the following subjects: histologia, próstata, sistema reprodutor masculino, camundongo and pele. (Source: Lattes Curriculum)
The incidence of chronic diseases such as diabetes and obesity, as well as genetic diseases such as cancer, has increased in recent decades due to several socio-economic and environmental factors. Thus, interest in environmental factors that interfere without intra-uterine development and rnorphofunctional, genetic and epigenetic promovamzy, including how they can be transmitted to offs...
The incidence of chronic diseases such as diabetes and obesity, as well as genetic diseases such as cancer, has increased in recent decades due to several socioeconomic and environmental factors that seem to interfere in the development, incidence and prognosis of these diseases. With regard to cancer, the temporal factor distances in up to 50-60 years the stages of initiation and tumor...
Prostate cancer is related to the endocrine system and its progression involves changes in estrogen and androgen signaling pathways. Therefore the investigation of drugs that interfere in these pathways creates perspective for discovery of novel therapeutic targets.In this scenario, androgen deprivation has been used as the main treatment for tumor reduction.The antiandrogen abiraterone...
(Only some records are available in English at this moment)
Environmental factors have influenced the intrauterine microenvironment, which has had important consequences on late development due to the actuation of these substances as endocrine disruptors. It should be noticed that most of these substances are commonly found in food packaging materials, children's toys, nail polishes, special care products. Phthalates represent a group of ubiquit...
The intrauterine microenvironment has been significantly altered due to the interference of environmental and/or socioeconomic factors, which can generate late and transgenerational consequences. Phthalates represent a class of molecules detected in different concentrations in breast milk, urine of pregnant women, amniotic fluid and human and rodents placenta. Previous studies have show...
Infertility affects 10-15% of couples on reproductive age and male factor may be responsible for 30-50% of cases. Studies suggest that 60-70% male infertility cases are considered idiophatic, once the molecular mechanisms involved in spermatogenesis are still unknown. Male fertility and spermatogenesis process are directly related to the ability of Sertoli cells to produce factors for g...
Zinc is an essential trace element for living organisms due to its numerous biological activities. It acts as a growth factor and immunoregulatory and presents antioxidant and anti-inflammatory properties. To be involved in many aspects of cellular physiology, including structural and functional conditions, the change in their levels during normal sexual development can modulate a serie...
The mono-n-butyl phthalate (MBP) - active metabolite of di-n-butyl phthalate, a plasticizer commonly used in many products, including medical devices, cosmetics and flexible plastics - has estrogenic effect, changing the estrogen dependent and/or independent signaling pathways during development of the male reproductive system. Recently, it is believed that the effects of endocrine disr...
(Only some records are available in English at this moment)
The incidence of chronic diseases such as diabetes and obesity, as well as genetic diseases such as cancer, has increased in recent decades due to several socioeconomic and environmental factors that seem to interfere in the development, incidence and prognosis of these diseases. Regarding cancer, the temporal factor distances up to 50-60 years the stages of initiation and tumor progres...
Male fertility and spermatogenesis process are directly related to the ability of Sertoli cells to produce factors associated with germ cells development. Only the Sertoli cells have receptors for FSH and testosterone, and therefore these cells are the major spermatogenesis regulators. Studies suggest that 60-70% male infertility cases are considered idiophatic, since the molecular mech...
| 1 / 1 | Ongoing research grants |
| 5 / 5 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 18 / 15 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 28 / 25 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 14 |
| Citations | 83 |
| Cit./Article | 5.9 |
| Data from Web of Science | |
SCARANO, WELLERSON R.; BEDRAT, AMINA; ALONSO-COSTA, LUIZ G.; AQUINO, ARIANA M.; FANTINATTI, BRUNO E. A.; JUSTULIN, LUIS A.; BARBISAN, LUIS F.; FREIRE, PAULA P.; FLAWS, JODI A.; LEMOS, BERNARDO. Exposure to an Environmentally Relevant Phthalate Mixture During Prostate Development Induces MicroRNA Upregulation and Transcriptome Modulation in Rats. TOXICOLOGICAL SCIENCES, v. 171, n. 1, p. 84-97, SEP 2019. Web of Science Citations: 0. (17/22275-2, 17/08306-2, 18/50002-3)
RIBEIRO, MARIANA A.; ESTILL, MOLLY S.; FERNANDEZ, GEYSSON J.; MORAES, LEONARDO N.; KRAWETZ, STEPHEN A.; SCARANO, WELLERSON R.. Integrative transcriptome and microRNome analysis identifies dysregulated pathways in human Sertoli cells exposed to TCDD. Toxicology, v. 409, p. 112-118, NOV 1 2018. Web of Science Citations: 3. (13/12154-2)
RIBEIRO SILVEIRA, LIVIA TERESA; SANTOS, TALITA DE MELLO; CAMORA, LUCAS FREDINI; PINHO, CRISTIANE FIGUEIREDO; ANSELMO-FRANCI, JANETE A.; DOMENICONI, RAQUEL FANTIN; JUSTULIN, LUIS ANTONIO; BARBISAN, LUIS FERNANDO; SCARANO, WELLERSON RODRIGO. Protective effect of resveratrol on urogenital sinus and prostate development in rats exposed in utero to TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin). REPRODUCTIVE TOXICOLOGY, v. 83, p. 82-92, JAN 2019. Web of Science Citations: 1. (13/04401-0)
SALATA, GIOVANNA CASSONE; PINHO, CRISTIANE FIGUEIREDO; DE FREITAS, ANDRE T. A. G.; AQUINO, ARIANA MUSA; JUSTULIN, LUIS ANTONIO; MENDES, LEONARDO OLIVEIRA; GONCALVES, BIANCA F.; DELELLA, FLAVIA KARINA; SCARANO, WELLERSON RODRIGO. Raloxifene decreases cell viability and migratory potential in prostate cancer cells (LNCaP) with GPR30/GPER1 involvement. Journal of Pharmacy and Pharmacology, v. 71, n. 7, p. 1065-1071, JUL 2019. Web of Science Citations: 0. (14/14202-7)
SCARANO‚ W.R.; CORDEIRO‚ R.S.; GÓES‚ R.M.; CARVALHO‚ H.F.; TABOGA‚ S.R.. Tissue remodeling in Guinea pig lateral prostate at different ages after estradiol treatment. Cell Biology International, v. 29, n. 9, p. 778-784, 2005.
PINHO, CRISTIANE F.; RIBEIRO, MARIANA A.; RINALDI, JAQUELINE C.; FELISBINO, SERGIO L.; PINHEIRO, PATRICIA F.; DOMENICONI, RAQUEL F.; FOCHI, RICARDO A.; BOER, PATRICIA A.; SCARANO, WELLERSON R.. Gestational protein restriction delays prostate morphogenesis in male rats. REPRODUCTION FERTILITY AND DEVELOPMENT, v. 26, n. 7, p. 967-973, 2014. Web of Science Citations: 6. (11/09061-7)
RIBEIRO, MARIANA ANTUNES; DOS REIS, MARIANA BISARRO; DE MORAES, LEONARDO NAZARIO; BRITON-JONES, CHRISTINE; RAINHO, CLAUDIA APARECIDA; SCARANO, WELLERSON RODRIGO. Defining suitable reference genes for RT-qPCR analysis on human sertoli cells after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. MOLECULAR BIOLOGY REPORTS, v. 41, n. 11, p. 7063-7066, NOV 2014. Web of Science Citations: 4. (11/04202-1, 12/00253-3)
BRANDT, JOYCE ZALOTTI; SILVEIRA, LIVIA TERESA R.; GRASSI, TONY FERNANDO; ANSELMO-FRANCI, JANETE A.; FAVARO, WAGNER JOSE; FELISBINO, SERGIO LUIS; BARBISAN, LUIS FERNANDO; SCARANO, WELLERSON RODRIGO. Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats. REPRODUCTIVE TOXICOLOGY, v. 43, p. 56-66, JAN 2014. Web of Science Citations: 17. (10/14110-4, 10/17262-0, 11/01954-2)
SCARANO, WELLERSON RODRIGO; DE TOLEDO, FABIOLA CHOQUETA; GUERRA, MARINA TREVIZAN; PEGORIN DE CAMPOS, SILVANA GISELE; JUSTULIN JUNIOR, LUIS ANTONIO; FELISBINO, SERGIO LUIS; ANSELMO-FRANCI, JANETE A.; TABOGA, SEBASTIAO ROBERTO; KEMPINAS, WILMA DE GRAVA. Long-term effects of developmental exposure to di-n-butyl-phthalate (DBP) on rat prostate: Proliferative and inflammatory disorders and a possible role of androgens. Toxicology, v. 262, n. 3, p. 215-223, AUG 21 2009. Web of Science Citations: 32.
GONCALVES, BIANCA FACCHIM; PEGORIN DE CAMPOS, SILVANA GISELE; FAVARO, WAGNER JOSE; BRANDT, JOYCE ZALOTTI; PINHO, CRISTIANE FIGUEIREDO; JUSTULIN, LUIS ANTONIO; TABOGA, SEBASTIAO ROBERTO; SCARANO, WELLERSON RODRIGO. Combinatorial Effect of Abiraterone Acetate and NVP-BEZ235 on Prostate Tumor Progression in Rats. HORMONES & CANCER, v. 9, n. 3, p. 175-187, JUN 2018. Web of Science Citations: 2. (14/14202-7, 13/22604-5)
PEIXOTO, ANDRE R.; SANTOS, TALITA M.; BRANDT, JOYCE Z.; DELELLA, FLAVIA K.; GONCALVES, BIANCA F.; CAMPOS, SILVANA G. P.; TABOGA, SEBASTIAO R.; FAVARO, WAGNER J.; DOMENICONI, RAQUEL F.; SCARANO, WELLERSON R.. Gestational and lactational exposition to Di-N-butyl-phthalate (DBP) increases inflammation and preneoplastic lesions in prostate of wistar rats after carcinogenic N-methyl-N-nitrosourea (MNU) plus testosterone protocol. ENVIRONMENTAL TOXICOLOGY, v. 31, n. 10, p. 1185-1195, OCT 2016. Web of Science Citations: 5. (11/06633-0, 11/10105-9, 10/01143-1)
SANTANA, VIVIANE P.; SALLES, EVILA S.; CORREA, DEBORAH E.; GONCALVES, BIANCA F.; CAMPOS, SILVANA G.; JUSTULIN, LUIZ A.; GODINHO, ANTONIO F.; SCARANO, WELLERSON R.. Long-term effects of perinatal exposure to low doses of cadmium on the prostate of adult male rats. International Journal of Experimental Pathology, v. 97, n. 4, p. 310-316, AUG 2016. Web of Science Citations: 3. (10/05979-7)
DE FREITAS, ANDRE TEVES A. G.; PINHO, CRISTIANE FIGUEIREDO; DE AQUINO, ARIANA MUSA; FERNANDES, ANA ANGELICA H.; DOMENICONI, RAQUEL FANTIN; JUSTULIN, LUIS ANTONIO; SCARANO, WELLERSON RODRIGO. Panax ginseng methabolit (GIM-1) prevents oxidative stress and apoptosis in human Sertoli cells exposed to Monobutyl-phthalate (MBP). REPRODUCTIVE TOXICOLOGY, v. 86, p. 68-75, JUN 2019. Web of Science Citations: 0. (12/00253-3)
CAMORA, LUCAS F.; SILVA, ANA PRISCILA G.; SANTOS, SERGIO A. A.; JUSTULIN, LUIS A.; PEROBELLI, JULIANA E.; BARBISAN, LUIS FERNANDO; SCARANO, WELLERSON R.. Impact of maternal and postnatal zinc dietary status on the prostate of pubescent and adult rats. Cell Biology International, v. 41, n. 11, SI, p. 1203-1213, NOV 2017. Web of Science Citations: 1. (14/25932-6)
AQUINO GONCALVES DE FREITAS, ANDRE TEVES; RIBEIRO, MARIANA ANTUNES; PINHO, CRISTIANE FIGUEIREDO; PEIXOTO, ANDRE REBELO; DOMENICONI, RAQUEL FANTIN; SCARANO, WELLERSON R.. Regulatory and junctional proteins of the blood-testis barrier in human Sertoli cells are modified by monobutyl phthalate (MBP) and bisphenol A (BPA) exposure. TOXICOLOGY IN VITRO, v. 34, p. 1-7, AUG 2016. Web of Science Citations: 9. (12/00253-3)
(References retrieved automatically from State of São Paulo Research Institutions)
SCARANO, Wellerson Rodrigo. Efeito do estradiol sobre a prostata da cobaia Cavia porcellus em diferentes fases do desenvolvimento pos-natal. Dissertação (Mestrado) - Instituto de Biologia. Universidade Estadual de Campinas. (00/06136-1)
PEIXOTO, Andre Rebelo. Caracterização dos efeitos celulares do Mono-N-butil-ftalato (MBP) mediados pela via estrogênica não-genômica ativada por GPER1 (GPR30) em células tumorais prostáticas humanas. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências (Campus de Botucatu). (14/09191-6)
RIBEIRO, Mariana Antunes. Reconstrução de redes regulatórias gênicas em células de Sertoli humanas expostas ao 2,3,7,8-Tetraclorodibenzo-p-dioxina (TCDD). Tese (Doutorado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências (Campus de Botucatu). (13/12154-2)
PINHO, Cristiane Figueiredo. Potential quimioprotetor do DIM (3, 3' - Di-indolil-metano) e da Genisteína em linhagens de células tumorais prostáticas humanas LNCaP e PC-3 expostas ao Bisfenol A. 46 f. Dissertação (Mestrado) - Universidade Estadual Paulista "Júlio de Mesquita Filho" Instituto de Biociências (Campus de Botucatu). (13/05038-6)