MD and PhD degrees (in 1999 and 2005, respectively) from the State University of Campinas, Sao Paulo, Brazil (UNICAMP). Residency training in Anatomic Pathology and Cytopathology at Hospital de Clinicas (UNICAMP), 2000-2003. Board certified in Anatomic Pathology and Cytopathology by the Brazilian Society of Pathology and the Brazilian Medical Association (in 2002). Professor of Pharmacology and Pathology at the School of Medical Sciences (Department of Translational Medicine) - UNICAMP (2009-). Concentrates in Cancer Stem Cell biomarkers as targets for the development of new therapeutical strategies and in the Toxicological Pathology of Nanomolecules. (Source: Lattes Curriculum)
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Neoplastic or cancer stem cells (CSCs) are tumor cells which are able to mimic phenotypic and functional features of adult stem cells, such as self-renewal and multilineage potential. In addition, CSCs are resistent to the majority of xenobiotics (including classic antineoplastic drugs) since they present low proliferative index and express efflux pumps (such as Pgp and ABCG2). These char…
In malignant neoplasms, angiogenesis seems to facilitate tumour growth and metastasis, thus, bearing a potential role in diagnostic/prognostic assessment, as well as in the development of new therapeutic strategies. However, the relative importance of such a role is variable from one entity to another, probably reflecting biological differences between tumours, as well as limitations or m…
Stem cells (SCs) are characterized by the capacity for self-renewal and multilineage differentiation and participate actively in countless physiologic and pathologic processes. Recently, in a new paradigm for carcinogenesis, SCs have been regarded as responsible for the origin, morphologic heterogeneity and self-renewal of malignant neoplasms. In support of this theory, it has been detect…
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| 3 / 2 | Completed research grants |
| 7 / 6 | Completed scholarships in Brazil |
| 10 / 8 | All research grants and scholarships |
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CV Lattes
ORCID