graduation at Farmácia Industrial from Universidade de São Paulo (1991), master's at Genetics from Universidade de São Paulo (1997) and doctorate at Tecnologia Bioquímica Farmacêutica from Universidade de São Paulo (2002). Has experience in Pharmacy, acting on the following subjects: vacinas, streptococcus pneumoniae, cultivo submerso, polissacarídeos capsulares and downstream processing. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Our studies have demonstrated the advantages of Mycobacterium bovis BCG as an antigen presenting system in the development of new vaccines. The project aims to expand the use of methods of heterologous gene expression in BCG developed in our laboratories with the aim of proposing new vaccines in the immunization against Pertussis, Tuberculosis, Pneumococcus and Schistosome, and to improve…
Streptococcus pneumoniae utilizes as a portal of entry into the body causing community acquired-pneumonia (CAP), bacteraemia, meningitis and sepsis (invasive pneumococcal disease, IPD). Current pneumococcal conjugate vaccine (PCV13) comprises 13 of the most common S. pneumoniase serotypes and is administered via the parental route resulting in low levels of lung mucosal immunity. Several …
(Only some records are available in English at this moment)
Streptococcus pneumoniae can cause a series of human infections leading to multiple health hazards, such as pneumonia, meningitis, bacteremia and sepsis. Pneumococcal vaccines currently on the market are based on polysaccharides and have limited coverage against the nearly 100 serotypes described. Although polysaccharide-based vaccines are important in preventing disease and decreasing th…
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis and is one of the main causes of death in the world. The attenuated live vaccine produced with the Calmette-Guérin bacillus (BCG) is the only one available against human TB and it is administrated as one dose on birth. However, BCG has low efficiency against pulmonary TB in adolescents and adults, and for this…
Zika Vírus (ZIKV) is an arbovirus that belongs to the Flaviviridae family and Flavivirus genus. It is capable of infecting humans and causing neurological complications, including Guillain-Barré Syndrome and Microcephaly. The main function of ZIKV envelope E protein is the interaction with cell receptors to promote the fusion between viral envelope and host cell membrane. The E protein is…
Streptococcus pneumoniae is an important human pathogen that causes severe diseases with high mortality rates. Pneumococcal vaccines are based on capsular polysaccharides, but their production cost is high and their coverage is limited to the serotypes included in the formulation. Thus, the protein vaccines have been investigated as an alternative. Among the studied candidates highlights …
(Only some records are available in English at this moment)
EDIII is the most exposed region of Zika Virus E protein and evokes potentneutralizing antibodies. It has the required characteristics to be used as a safe andeffective antigen for a subunit Zika vaccine. EDIII production in E. coli has beenreported only at lab-scale and mostly refolded from inclusion bodies (IB), which isdifficult to scale-up maintaining protein function. Fusion tag tech…
| 1 / 1 | Ongoing research grants |
| 7 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 8 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 18 / 15 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID