Fernanda Calheta Vieira Portaro

• Abstract

  Scorpionism has grown alarmingly in Brazil in recent years. The occurrence of accidents is associated with the adaptation and proliferation of scorpions in urban areas, where they find shelter, food, and the absence of natural predators. Along with this, the yellow scorpion (Tityus serrulatus), the species responsible for the greatest number of serious accidents, reproduces by parthenogen…

  Study of the proteases and peptides present in the Tityus serrulatus scorpion venom: deepening knowledge on the venom and seeking for new therapies aimed at treating envenomation, AP.R

• Abstract

  Currently, cases of scorpion accidents involving humans are considered a public health problem in Brazil, and the numbers of such accidents surpass the reported data with other venomous animals such as snakes and spiders. The scorpions from Tityus genus are mainly responsible for such situation and, among them, the Tityus serrulatus (yellow scorpion) is the most important. This relevance …

  Toxic potential analysis of proteases and peptides present in scorpion Tityus serrulatus venom and the blockage capacity of commercial antivenoms: Enhancing the knowledge of venom and its mechanism of action., AP.R

• Abstract

  Although the ophidian poisoning overcome various other neglected tropical diseases in terms of number of occurrence and deaths, such as leishmaniasis, dengue, schistosomiasis, cholera and Chagas disease, it was only recently recognized as an important issue of public health. The genus Bothrops is considered the most important in the cases of poisoning in Brazil and, as well as on other sn…

  Study of peptidase activity of the B. jararaca venom and potential neutralizing serum produced at Instituto Butantan upon this activity: new aspects of Bothrops poisoning, AP.R

(Only some records are available in English at this moment)

• Abstract

  Scorpionism is considered a public health problem in countries with tropical and subtropical climates. Scorpions of the Tityus genus are considered the most dangerous in South America and are responsible for most of the envenoming and fatalities. In Brazil, the Tityus serrulatus is the main responsible for accidents, due to the toxicity of its venom, which induces local and systemic infla…

  In silico and biological characterization of peptides present in scorpion venom Tityus serrulatus, BP.MS

• Abstract

  Peptidases are essential for the proper physiological activities of the various organisms, from protozoa to large mammals. However, a deregulation of these activities may be the cause of severe pathologies. One of these is calpain, a cysteine peptidase which is found in a seven-time higher concentration in animals that have developed Alzheimer disease, when compared to normal animals. Ano…

  Purification and characterization of peptides present in the venom of African snakes: searching for peptidase inhibitor of medical importance, BP.DR

• Abstract

  Accidents caused by scorpion represent a relevant public health problem in Brazil, being more recurring than incidents caused by spiders and snakes. The main specie responsible for scorpionism in this country is the scorpion Tityus serrulatus due their reproductive strategy, the parthenogenesis, and the potential of its venom to induce severe, or even fatal, clinical events, especially am…

  Purification and characterization of peptides present in the venom of the scorpion Tityus serrulatus, BP.DR

(Only some records are available in English at this moment)