Mário Tyago Murakami
CV Lattes
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Ministério da Ciência, Tecnologia, Inovações e Comunicações (Brasil). Centro Nacional de Pesquisa em Energia e Materiais (CNPEM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Engenharia from Universidade Estadual Paulista Júlio de Mesquita Filho (2003) and doctorate at Byophysics from Universidade Estadual Paulista Júlio de Mesquita Filho (2006). Has experience in Byophysics, acting on the following subjects: estrutura-função de proteínas, difração de raios x, fosfolipases a2, cristalização and purificação. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| Key enzyme for production of second-generation ethanol discovered in Brazilian Amazon |
- Exploring novel strategies for depolymerization of plant cell-wall polysaccharides: from structure, function and rational design of glycosyl hydrolases to biological implications and potential biotechnological applications, AP.TEM
Abstract
The plant cell wall is an important physical barrier to pathogens, and to chemical and physical stress for plants and it is essentially composed of polysaccharides of great biological and industrial importance. However, the challenge to deconstruct the plant cell wall into simple sugars is not a fully consolidated and economically viable process for many industrial applications as, for ...
- Studies of the role of phosphorylation and protein binding partners in regulating the function of human class V myosins, AP.R
Abstract
In this next project we will continue our studies regarding the class V myosins (MyoVs). The combination of structural and functional approaches will be maintained as in the previous project and our goal will be to answer new questions that arose during these two years of work. First, we want to know what the role of phosphorylation in regulating the CBD function of mammalian MyoVs. To ...
- Multi-user equipament approved in grant 2013/13309-0: Beckman Coulter capillary electrophoresis systems with LIF detection system, AP.EMU
Abstract
The structure-function relationship studies of glycoside hydrolases contribute to unveil new strategies to improve thermal stability, specificity, and modulation - knowledge that can be used for the development of optimized enzymes for biotechnological processes as well as to assist the rational design of enzymes. However, studies regarding the structural determinants for the different ...
- Structural insights into functional overlapping and differentiation among myosin v motors, PUB.ART
Abstract
Myosin V (MyoV) motors have been implicated in the intracellular transport of diverse cargoes including vesicles, organelles, RNA-protein complexes, and regulatory proteins. Here,we have solved the cargo-binding domain (CBD) structures of the three human MyoV paralogs (Va, Vb, and Vc), revealing subtle structural changes that drive functional differentiation and anovel redox mechanism c...
(Only some records are available in English at this moment)
- Production, purification and structural studies of accessory enzymes for xylan degradation, BP.TT
- Understanding the molecular system of degradation and utilization of cellulose by the phytopathogen Xanthomonas citri subsp. citri, BP.DR
Abstract
The genus Xanthomonas is composed of gram-negative bacteria capable of infecting different plant species, many of them of great economic and social importance, such as rice and orange. Brazil as the second largest producer of citrus fruits in the world for decades is concerned with Citrus Canker disease, caused by the presence of the bacterium Xanthomonas citri subsp. citri, which has h...
- Evaluation of the biotechnological potential of the cellulolytic system of Xanthomonas axonopodis PV. citri: a structural, functional and applied approach, BP.PD
Abstract
Due to the heterogeneity and recalcitrance of lignocellulosic biomass its complete and efficient degradation is a challenge to be overcome aiming the economic viability of some bioprocesses, such as the cellulosic ethanol. One of the main factors that contribute for this is the absence of efficient and low cost enzymatic cocktails. Plant pathogens found in Xanthomonadaceae family, parti...
(Only some records are available in English at this moment)
- Analysis of structural and functional diversity of GH43 enzymes from Xanthomonas axonopodis PV. citri: biological implications and potential biotechnological applications, BP.PD
Abstract
Plant cell wall degradative enzymes have attracted great interest of scientists due to their many biological roles and industrial applications such as in biofuels, paper, textiles, food and beverage production processes. However, the depolymerization of plant cell wall by enzymatic routes is neither a fully consolidated process nor economically viable, being necessary the development of...
- Elucidation of the mechanistic basis of family GH62 present in organisms specialized in the degradation of plant biomass, BP.PD
Abstract
The bioconversion of lignocellulosic materials, particularly agro-industrial residues for ethanol production has increasingly attracted the attention of researchers as a source of renewable energy that can replace fossil fuels , reducing the environmental impact . Initially, many studies have been focused on the understanding and development of technologies for the bioconversion of cell...
- Structural and biotechnological aspects of two novel cellulases belonging to families GH5 (Xac0030) and GH9 (Xac2522) from the plant pathogen Xanthomonas axonopodis PV. citri, BP.PD
Abstract
The use of biomass as a renewable source of energy has become a major strategy for replacement of current energy matrix based on fossil fuels. The main constituent of biomass is cellulose that is basically comprised of glucose molecules covalently linked by b-1,4 linkages. However, it is extremely recalcitrant to degradation by enzymatic routes. For hydrolysis of the cellulosic fraction...
(Only some records are available in English at this moment)
- Directed evolution of Xanthomonas axonopodis PV. citri beta-galactosidase, BE.EP.PD
Abstract
Primary cell walls of plants are mainly composed by cellulose and hemicellulose, having xyloglucan (XyG) as the main hemicellulosic polysaccharide. The XyG structure and composition largely varies according to plant type and tissue requiring a diverse and complex repertoire of glycosyl hydrolases to be depolymerized. The genus Xanthomonas poses as one of the most widespread pathogenic b...
- Unveiling the calcium role on GH43 beta-xylosidases / alpha-L-arabinofuranosidases catalysis by QM/MM molecular dynamics methods, BE.EP.PD
Abstract
Glycoside hydrolases from family 43 (GH43) act on the degradation of key polysaccharides that constitute the hemicellulose such as xylan and arabinans. However, despite this family having a strong correlation with plant cell wall deconstruction and being ubiquitous in plant biomass maceration specialized organisms, it is still poorly explored. GH43 is a very polyspecific family, divided...
- Ancestral reconstruction of the GH5_18 beta-mannosidase from Bifidobacterium longum, BE.EP.DD
Abstract
The family 5 of glycoside hydrolases (GH5) consists of more than 12000 members that recognize and hydrolyze a broad range of carbohydrates. For a better understanding of the great diversity of its enzymatic repertoire, Asperborg et al. (2012) classified the GH5 family into 51 subfamilies, from which 20 did not have available characterization data so far. In the current FAPESP doctoral p...
- Functional characterization of the mitochondrial peroxiredoxin I from Leishmania braziliensis evaluating the peroxidase and chaperone activity, BE.EP.DD
Abstract
Peroxiredoxins (Prxs) belonging to the subfamily Prx1, are typical 2-Cys peroxidases responsible for controlling the intracellular level of H2O2 and seem to assume a chaperone function under oxidative stress conditions. Members of this subfamily have two catalytic cysteines and constitute two homodimers with identical active sites located on opposite sides. In most cases, these dimers c...
- Ab initio structure solution with ARCIMBOLDO of myosins and other highly helical proteins at resolutions below 2 Å, BE.EP.DD
Abstract
The macromolecular crystallography is one of most important tools in structural biology and it has been responsible for nearly 95% of protein structures deposited at the Protein Data Bank (PDB). However, the elucidation of a macromolecular crystallographic structure involves several empirical and laborious steps, which limit a higher success rate. Besides the difficulties observed in pr...
| 1 / 1 | Ongoing research grants |
| 6 / 6 | Completed research grants |
| 6 / 6 | Ongoing scholarships in Brazil |
| 19 / 15 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 3 / 3 | Completed scholarships abroad |
| 37 / 33 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 35 |
| Citations | 400 |
| Cit./Article | 11.4 |
| Data from Web of Science | |
DOS SANTOS, CAMILA RAMOS; PAIVA, JOICE HELENA; MEZA, ANDREIA NAVARRO; COTA, JUNIO; ALVAREZ, THABATA MARIA; RULLER, ROBERTO; PRADE, ROLF ALEXANDER; SQUINA, FABIO MARCIO; MURAKAMI, MARIO TYAGO. Molecular insights into substrate specificity and thermal stability of a bacterial GH5-CBM27 endo-1,4-beta-D-mannanase. Journal of Structural Biology, v. 177, n. 2, p. 469-476, FEB 2012. Web of Science Citations: 18. (10/51890-8)
SANTOS, CAMILA RAMOS; POLO, CARLA CRISTINA; CORREA, JULIANA MOCO; GARCIA SIMAO, RITA DE CASSIA; VICENTE SEIXAS, FLAVIO AUGUSTO; MURAKAMI, MARIO TYAGO. The accessory domain changes the accessibility and molecular topography of the catalytic interface in monomeric GH39 ss-xylosidases. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, v. 68, n. 10, p. 1339-1345, OCT 2012. Web of Science Citations: 11. (10/51890-8)
SANTOS, CAMILA R.; PAIVA, JOICE H.; SFORCA, MAURICIO L.; NEVES, JORGE L.; NAVARRO, RODRIGO Z.; COTA, JUNIO; AKAO, PATRICIA K.; HOFFMAM, ZAIRA B.; MEZA, ANDREIA N.; SMETANA, JULIANA H.; et al. Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168. Biochemical Journal, v. 441, n. 1, p. 95-104, JAN 1 2012. Web of Science Citations: 49. (10/51890-8)
DE GIUSEPPE, PRISCILA O.; MARTINS, NADIA H.; MEZA, ANDREIA N.; DOS SANTOS, CAMILA R.; PEREIRA, HUMBERTO D'MUNIZ; MURAKAMI, MARIO T.. Insights into Phosphate Cooperativity and Influence of Substrate Modifications on Binding and Catalysis of Hexameric Purine Nucleoside Phosphorylases. PLoS One, v. 7, n. 9, SEP 5 2012. Web of Science Citations: 7. (10/51890-8)
FURTADO, GILVAN P.; SANTOS, CAMILA R.; CORDEIRO, ROSA L.; RIBEIRO, LUCAS F.; DE MORAES, LUIZ A. B.; DAMASIO, ANDR R. L.; POLIZELI, MARIA DE LOURDES T. M.; LOURENZONI, MARCOS R.; MURAKAMI, MARIO T.; WARD, RICHARD J.. Enhanced xyloglucan-specific endo-beta-1,4-glucanase efficiency in an engineered CBM44-XegA chimera. Applied Microbiology and Biotechnology, v. 99, n. 12, p. 5095-5107, JUN 2015. Web of Science Citations: 10. (10/18850-2, 14/07135-1, 10/07133-8, 13/13309-0, 12/20549-4, 13/18910-3)
DIOGO, JOSE A.; HOFFMAM, ZAIRA B.; ZANPHORLIN, LETICIA M.; COTA, JUNIO; MACHADO, CARLA B.; WOLF, LUCIA D.; SQUINA, FABIO; DAMASIO, ANDRE R. L.; MURAKAMI, MARIO T.; RULLER, ROBERTO. Development of a chimeric hemicellulase to enhance the xylose production and thermotolerance. Enzyme and Microbial Technology, v. 69, p. 31-37, FEB 2015. Web of Science Citations: 10. (13/10443-7, 08/58037-9, 11/14200-6)
NASCIMENTO, ANDREY F. Z.; TRINDADE, DANIEL M.; TONOLI, CELISA C. C.; DE GIUSEPPE, PRISCILA O.; ASSIS, LEANDRO H. P.; HONORATO, RODRIGO V.; DE OLIVEIRA, PAULO S. L.; MAHAJAN, PRAVIN; BURGESS-BROWN, NICOLA A.; VON DELFT, FRANK; et al. Structural Insights into Functional Overlapping and Differentiation among Myosin V Motors. Journal of Biological Chemistry, v. 288, n. 47, p. 34131-34145, NOV 22 2013. Web of Science Citations: 16. (09/08312-6)
HOFFMAM, ZAIRA B.; OLIVEIRA, LEANDRO C.; COTA, JUNIO; ALVAREZ, THABATA M.; DIOGO, JOS A.; NETO, MARIO DE OLIVEIRA; CITADINI, ANA PAULA S.; LEITE, VITOR B. P.; SQUINA, FABIO M.; MURAKAMI, MARIO T.; et al. Characterization of a Hexameric Exo-Acting GH51 alpha-l-Arabinofuranosidase from the Mesophilic Bacillus subtilis. MOLECULAR BIOTECHNOLOGY, v. 55, n. 3, p. 260-267, NOV 2013. Web of Science Citations: 7. (11/13242-7, 10/51890-8, 11/14200-6, 11/17658-3, 08/58037-9)
MORAIS, MARIANA A. B.; GIUSEPPE, PRISCILA O.; SOUZA, TATIANA A. C. B.; ALEGRIA, THIAGO G. P.; OLIVEIRA, MARCOS A.; NETTO, LUIS E. S.; MURAKAMI, MARIO T.. How pH Modulates the Dimer-Decamer Interconversion of 2-Cys Peroxiredoxins from the Prx1 Subfamily. Journal of Biological Chemistry, v. 290, n. 13, p. 8582-8590, MAR 27 2015. Web of Science Citations: 23. (12/24134-3, 11/10248-4, 10/51730-0)
DOS SANTOS, CAMILA RAMOS; CORDEIRO, ROSA LORIZOLLA; WONG, DOMINIC W. S.; MURAKAMI, MARIO TYAGO. Structural Basis for Xyloglucan Specificity and alpha-D-Xylp(1 -> 6)-D-Glcp Recognition at the-1 Subsite within the GH5 Family. BIOCHEMISTRY, v. 54, n. 10, p. 1930-1942, MAR 17 2015. Web of Science Citations: 8. (10/51890-8, 13/13309-0)
FURTADO, GILVAN PESSOA; RIBEIRO, LUCAS FERREIRA; SANTOS, CAMILA RAMOS; TONOLI, CELISA CALDANA; DE SOUZA, ANGELICA RODRIGUES; OLIVEIRA, RENATA ROCHA; MURAKAMI, MARIO TYAGO; WARD, RICHARD JOHN. Biochemical and structural characterization of a beta-1,3-1,4-glucanase from Bacillus subtilis 168. Process Biochemistry, v. 46, n. 5, p. 1202-1206, MAY 2011. Web of Science Citations: 29. (07/01615-8, 10/51890-8, 07/01623-0, 08/57908-6)
SANTOS, CAMILA R.; POLO, CARLA C.; COSTA, MARIA C. M. F.; NASCIMENTO, ANDREY F. Z.; MEZA, ANDREIA N.; COTA, JUNIO; HOFFMAM, ZAIRA B.; HONORATO, RODRIGO V.; OLIVEIRA, PAULO S. L.; GOLDMAN, GUSTAVO H.; et al. Mechanistic Strategies for Catalysis Adopted by Evolutionary Distinct Family 43 Arabinanases. Journal of Biological Chemistry, v. 289, n. 11, p. 7362-7373, MAR 14 2014. Web of Science Citations: 13. (10/51890-8, 13/13309-0)
ALVAREZ, THABATA M.; PAIVA, JOICE H.; RUIZ, DIEGO M.; CAIRO, JOAO PAULO L. F.; PEREIRA, ISABELA O.; PAIXAO, DOUGLAS A. A.; DE ALMEIDA, RODRIGO F.; TONOLI, CELISA C. C.; RULLER, ROBERTO; SANTOS, CAMILA R.; et al. Structure and Function of a Novel Cellulase 5 from Sugarcane Soil Metagenome. PLoS One, v. 8, n. 12, DEC 17 2013. Web of Science Citations: 23. (11/20977-3, 13/13309-0, 10/11469-1, 09/08312-6, 08/58037-9)
TOYAMA, DANYELLE; BUENO DE MORAIS, MARIANA ABRAHAO; RAMOS, FELIPE CARDOSO; ZANPHORLIN, LETICIA MARIA; COSTA TONOLI, CELISA CALDANA; BALULA, AUGUSTO FURIO; DE MIRANDA, FERNANDO FELTON; ALMEIDA, VITOR MEDEIROS; MARANA, SANDRO ROBERTO; RULLER, ROBERTO; et al. A novel beta-glucosidase isolated from the microbial metagenome of Lake Poraque (Amazon, Brazil). BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, v. 1866, n. 4, p. 569-579, APR 2018. Web of Science Citations: 3. (15/26982-0)
DE GIUSEPPE, PRISCILA OLIVEIRA; CAMPOS BRASIL SOUZA, TATIANA DE ARRUDA; MOREIRA SOUZA, FLAVIO HENRIQUE; ZANPHORLIN, LETICIA MARIA; MACHADO, CARLA BOTELHO; WARD, RICHARD JOHN; JORGE, JOAO ATILIO; MELO FURRIEL, ROSA DOS PRAZERES; MURAKAMI, MARIO TYAGO. Structural basis for glucose tolerance in GH1 beta-glucosidases. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, v. 70, n. 6, p. 1631-1639, JUN 2014. Web of Science Citations: 53. (09/08312-6, 13/13309-0)
BERTO, GABRIELA LEILA; VELASCO, JOSMAN; CABOS RIBEIRO, CAIO TASSO; ZANPHORLIN, LETICIA MARIA; DOMINGUES, MARIANE NORONHA; MURAKAMI, MARIO TYAGO; POLIKARPOV, IGOR; DE OLIVEIRA, LEANDRO CRISTANTE; FERRAZ, ANDRE; SEGATO, FERNANDO. Functional characterization and comparative analysis of two heterologous endoglucanases from diverging subfamilies of glycosyl hydrolase family 45. Enzyme and Microbial Technology, v. 120, p. 23-35, JAN 2019. Web of Science Citations: 2. (14/18714-2, 15/13684-0, 15/26982-0, 14/06923-6)
RODRIGUES DE MELO, RICARDO; CARLOS ALNOCH, ROBSON; DE SOUSA, AMANDA SILVA; SATO, HELIA HARUMI; RULLER, ROBERTO; MATEO, CESAR. Cross-Linking with Polyethylenimine Confers Better Functional Characteristics to an Immobilized beta-glucosidase from Exiguobacterium antarcticum B7. CATALYSTS, v. 9, n. 3, MAR 2019. Web of Science Citations: 0. (17/14253-9)
RIBEIRO CORREA, THAMY LIVIA; TOMAZINI JUNIOR, ATILIO; WOLF, LUCIA DANIELA; BUCKERIDGE, MARCOS SILVEIRA; DOS SANTOS, LEANDRO VIEIRA; MURAKAMI, MARIO TYAGO. An actinobacteria lytic polysaccharide monooxygenase acts on both cellulose and xylan to boost biomass saccharification. BIOTECHNOLOGY FOR BIOFUELS, v. 12, MAY 10 2019. Web of Science Citations: 0. (15/26982-0)
MURAKAMI‚ M.T.; ARNI‚ R.K.; VIEIRA‚ D.S.; DEGRÈVE‚ L.; RULLER‚ R.; WARD‚ R.J.. Correlation of temperature induced conformation change with optimum catalytic activity in the recombinant G/11 xylanase A from Bacillus subtilis strain 168 (1A1). FEBS Letters, v. 579, n. 28, p. 6505-6510, 2005. (03/01457-2)
SANTOS, CAMILA RAMOS; HOFFMAM, ZAIRA BRUNA; DE MATOS MARTINS, VANESA PEIXOTO; ZANPHORLIN, LETICIA MARIA; DE PAULA ASSIS, LEANDRO HENRIQUE; HONORATO, RODRIGO VARGAS; LOPES DE OLIVEIRA, PAULO SERGIO; RULLER, ROBERTO; MURAKAMI, MARIO TYAGO. Molecular Mechanisms Associated with Xylan Degradation by Xanthomonas Plant Pathogens. Journal of Biological Chemistry, v. 289, n. 46, p. 32186-32200, NOV 14 2014. Web of Science Citations: 22. (10/51890-8, 13/13309-0, 14/07135-1)
DIOGO, JOSE ALBERTO; ZANPHORLIN, LETICIA MARIA; SATO, HELIA HARUMI; MURAKAMI, MARIO TYAGO; RULLER, ROBERTO. Molecular cloning, overexpression, purification and crystallographic analysis of a GH43-xylosidase from Bacillus licheniformis. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, v. 71, n. 8, p. 962-965, AUG 2015. Web of Science Citations: 1. (13/13309-0, 13/10443-7, 14/07135-1)
RUIZ, DIEGO M.; TUROWSKI, VALERIA R.; MURAKAMI, MARIO T.. Effects of the linker region on the structure and function of modular GH5 cellulases. SCIENTIFIC REPORTS, v. 6, JUN 23 2016. Web of Science Citations: 16. (13/01583-0, 13/13309-0)
CRESPIM, ELAINE; ZANPHORLIN, LETICIA M.; DE SOUZA, FLAVIO H. M.; DIOGO, JOSE A.; GAZOLLA, ALEX C.; MACHADO, CARLA B.; FIGUEIREDO, FERNANDA; SOUSA, AMANDA S.; NOBREGA, FELIPE; PELLIZARI, VIVIAN H.; et al. A novel cold-adapted and glucose-tolerant GH1 beta-glucosidase from Exiguobacterium antarcticum B7. International Journal of Biological Macromolecules, v. 82, p. 375-380, JAN 2016. Web of Science Citations: 17. (13/13309-0, 14/07135-1)
VIEIRA, PLINIO SALMAZO; CAMPOS BRASIL SOUZA, TATIANA DE ARRUDA; HONORATO, RODRIGO VARGAS; ZANPHORLIN, LETICIA MARIA; SEVERIANO, KELVEN ULISSES; ROCCO, SILVANA APARECIDA; CAVALCANTE DE OLIVEIRA, ARTHUR HENRIQUE; CORDEIRO, ARTUR TORRES; LOPES OLIVEIRA, PAULO SERGIO; DE GIUSEPPE, PRISCILA OLIVEIRA; et al. Pyrrole-indolinone SU11652 targets the nucleoside diphosphate kinase from Leishmania parasites. Biochemical and Biophysical Research Communications, v. 488, n. 3, p. 461-465, JUL 1 2017. Web of Science Citations: 3. (11/20569-2, 11/24178-8, 07/06755-2, 10/03761-4, 10/51730-0)
MORAIS, MARIANA A. B.; GIUSEPPE, PRISCILA O.; SOUZA, TATIANA A. C. B.; CASTRO, HELENA; HONORATO, RODRIGO V.; OLIVEIRA, PAULO S. L.; NETTO, LUIS E. S.; TOMAS, ANA M.; MURAKAMI, MARIO T.. Calcium and magnesium ions modulate the oligomeric state and function of mitochondrial 2-Cys peroxiredoxins in Leishmania parasites. Journal of Biological Chemistry, v. 292, n. 17, p. 7023-7039, APR 28 2017. Web of Science Citations: 1. (12/24134-3, 15/05851-4, 11/10248-4, 10/51730-0)
NARESSI SCAPIN, SANDRA MARA; MOREIRA SOUZA, FLAVIO HENRIQUE; ZANPHORLIN, LETICIA MARIA; DE ALMEIDA, THAMYRES SILVA; SADE, YOUSSEF BACILA; CARDOSO, ALEXANDER MACHADO; PINHEIRO, GUILHERME LUIZ; MURAKAMI, MARIO TYAGO. Structure and function of a novel GH8 endoglucanase from the bacterial cellulose synthase complex of Raoultella ornithinolytica. PLoS One, v. 12, n. 4, APR 27 2017. Web of Science Citations: 5. (15/26982-0)
ASSIS, L. H. P.; SILVA-JUNIOR, R. M. P.; DOLCE, L. G.; ALBORGHETTI, M. R.; HONORATO, R. V.; NASCIMENTO, A. F. Z.; MELO-HANCHUK, T. D.; TRINDADE, D. M.; TONOLI, C. C. C.; SANTOS, C. T.; et al. The molecular motor Myosin Va interacts with the cilia-centrosomal protein RPGRIP1L. SCIENTIFIC REPORTS, v. 7, MAR 7 2017. Web of Science Citations: 14. (09/54014-7, 14/09720-9, 14/18189-5, 11/20229-7, 09/08312-6)
SANTOS, CLELTON A.; ZANPHORLIN, LET-CIA M.; CRUCELLO, ALINE; TONOLI, CELISA C. C.; RULLER, ROBERTO; HORTA, MARIA A. C.; MURAKAMI, MARIO T.; DE SOUZA, ANETE PEREIRA. Crystal structure and biochemical characterization of the recombinant ThBgl, a GH1 beta-glucosidase overexpressed in Trichoderma harzianum under biomass degradation conditions. BIOTECHNOLOGY FOR BIOFUELS, v. 9, MAR 22 2016. Web of Science Citations: 9. (08/52197-4, 14/09720-9, 13/13309-0, 14/18856-1)
ZANPHORLIN, LETICIA MARIA; DE GIUSEPPE, PRISCILA OLIVEIRA; HONORATO, RODRIGO VARGAS; COSTA TONOLI, CELISA CALDANA; FATTORI, JULIANA; CRESPIM, ELAINE; LOPES DE OLIVEIRA, PAULO SERGIO; RULLER, ROBERTO; MURAKAMI, MARIO TYAGO. Oligomerization as a strategy for cold adaptation: Structure and dynamics of the GH1 beta-glucosidase from Exiguobacterium antarcticum B7. SCIENTIFIC REPORTS, v. 6, MAR 31 2016. Web of Science Citations: 23. (13/13309-0, 14/07135-1)
VIEIRA, PLINIO SALMAZO; DE GIUSEPPE, PRISCILA OLIVEIRA; CAVALCANTE DE OLIVEIRA, ARTHUR HENRIQUE; MURAKAMI, MARIO TYAGO. The role of the C-terminus and Kpn loop in the quaternary structure stability of nucleoside diphosphate kinase from Leishmania parasites. Journal of Structural Biology, v. 192, n. 3, p. 336-341, DEC 2015. Web of Science Citations: 3. (11/20569-2, 11/24178-8, 07/06755-2, 10/03761-4, 10/51730-0)
CORDEIRO, ROSA LORIZOLLA; SIQUEIRA PIROLLA, RENAN AUGUSTO; PERSINOTI, GABRIELA FELIX; GOZZO, FABIO CESAR; DE GIUSEPPE, PRISCILA OLIVEIRA; MURAKAMI, MARIO TYAGO. N-glycan Utilization by Bifidobacterium Gut Symbionts Involves a Specialist beta-Mannosidase. Journal of Molecular Biology, v. 431, n. 4, p. 732-747, FEB 15 2019. Web of Science Citations: 0. (16/00740-2, 15/26982-0)
ZANPHORLIN, LETICIA MARIA; BUENO DE MORAIS, MARIANA ABRAHAO; DIOGO, JOSE ALBERTO; DOMINGUES, MARIANE NORONHA; MOREIRA DE SOUZA, FLAVIO HENRIQUE; RULLER, ROBERTO; MURAKAMI, MARIO TYAGO. Structure-guided design combined with evolutionary diversity led to the discovery of the xylose-releasing exo-xylanase activity in the glycoside hydrolase family 43. Biotechnology and Bioengineering, v. 116, n. 4, p. 734-744, APR 2019. Web of Science Citations: 0. (16/19995-0, 13/24622-0, 15/26982-0)
SANTOS, CLELTON A.; MORAIS, MARIANA A. B.; TERRETT, OLIVER M.; LYCZAKOWSKI, JAN J.; ZANPHORLIN, LETICIA M.; FERREIRA, JAIRE A.; TONOLI, CELISA C. C.; MURAKAMI, MARIO T.; DUPREE, PAUL; SOUZA, ANETE P.. An engineered GH1 ss-glucosidase displays enhanced glucose tolerance and increased sugar release from lignocellulosic materials. SCIENTIFIC REPORTS, v. 9, MAR 20 2019. Web of Science Citations: 0. (16/19995-0, 15/09202-0, 15/26982-0, 17/17390-7)
DOS SANTOS, CAMILA RAMOS; DE GIUSEPPE, PRISCILA OLIVEIRA; MOREIRA DE SOUZA, FLAVIO HENRIQUE; ZANPHORLIN, LETICIA MARIA; DOMINGUES, MARIANE NORONHA; SIQUEIRA PIROLLA, RENAN AUGUSTO; HONORATO, RODRIGO VARGAS; COSTA TONOLI, CELISA CALDANA; BUENO DE MORAIS, MARIANA ABRAHAO; DE MATOS MARTINS, VANESA PEIXOTO; et al. The mechanism by which a distinguishing arabinofuranosidase can cope with internal di-substitutions in arabinoxylans. BIOTECHNOLOGY FOR BIOFUELS, v. 11, AUG 11 2018. Web of Science Citations: 1. (14/17264-3, 13/13309-0, 15/26982-0, 14/07135-1)
DOMINGUES, MARIANE NORONHA; MOREIRA SOUZA, FLAVIO HENRIQUE; VIEIRA, PLINIO SALMAZO; BUENO DE MORAIS, MARIANA ABRAHAO; ZANPHORLIN, LETICIA MARIA; DOS SANTOS, CAMILA RAMOS; SIQUEIRA PIROLLA, RENAN AUGUSTO; HONORATO, RODRIGO VARGAS; LOPES DE OLIVEIRA, PAULO SERGIO; GOZZO, FABIO CESAR; et al. Structural basis of exo--mannanase activity in the GH2 family. Journal of Biological Chemistry, v. 293, n. 35, p. 13636-13649, AUG 31 2018. Web of Science Citations: 2. (16/19995-0, 13/24622-0, 15/26982-0, 16/06509-0)
DOLCE, LUCIANO G.; SILVA-JUNIOR, RUI M. P.; ASSIS, LEANDRO H. P.; NASCIMENTO, ANDREY F. Z.; ARAUJO, JACKELINE S.; MESCHEDE, INGRID P.; ESPREAFICO, ENILZA M.; DE GIUSEPPE, PRISCILA O.; MURAKAMI, MARIO T.. Myosin Va interacts with the exosomal protein spermine synthase. BIOSCIENCE REPORTS, v. 39, n. 3, MAR 29 2019. Web of Science Citations: 1. (14/09720-9, 14/00584-5, 14/03989-6, 11/20229-7, 09/14257-8, 16/10862-8, 18/04017-9, 13/08135-2)
(References retrieved automatically from State of São Paulo Research Institutions)
VIEIRA, Plínio Salmazo. Estrutura, conformação e inibição de quinases de Leishmania = Structure, conformation and inhibition of kinases from Leishmania. 2016. Tese (Doutorado) – Universidade Estadual de Campinas, Instituto de Biologia. (11/24178-8)
POLO, Carla Cristina. Investigação dos determinantes estruturais do modo de ação de endo e exo-arabinanases provenientes da microflora do rúmen bovino. 2016. Tese (Doutorado) – Universidade Estadual de Campinas, Instituto de Biologia. (12/09119-8)
PAIVA, Joice Helena. Estrutura, função e estabilidade de hidrolases gicosídicas pertencentes à família GH5 com potencial aplicação na conversão de biomassa lignocelulósica em açúcares fermentáveis = : Structure, function and stability of the glycosyl hidrolases that belong to GH5 family with potencial application in the conversion of lignocellulosic biomass in fermentable sugars. 2013. Tese (Doutorado) – Instituto de Biologia. Universidade Estadual de Campinas (UNICAMP). (08/10555-1)
MURAKAMI, Mário Tyago. Estratégias de inibição, mecanismos moleculares e interações intermoleculares em complexos macromoleculares. 2006. 152f. Tese (Doutorado) – Instituto de Biociências, Letras e Ciências Exatas. Universidade Estadual Paulista. São José do Rio Preto. (03/13082-3)
NASCIMENTO, Andrey Fabricio Ziem. Aspectos estruturais dos eventos moleculares associados à regulação e seletividade do transporte de cargas celulares pelas miosinas de classe V humanas. 2014. Tese (Doutorado) – Instituto de Biologia. Universidade Estadual de Campinas. (09/14257-8)
ASSIS, Leandro Henrique de Paula. A descoberta da interação entre miosina Va e RPGRIP1L = caracterização do complexo e localização no centrossomo = The discovery of the interaction between myosin Va and RPGRIP1L: characterization of the complex and localization at the centrosome. 2016. Tese (Doutorado) – Universidade Estadual de Campinas, Instituto de Biologia. (11/20229-7)
MORAIS, Mariana Abrahão Bueno de. Ca2+, Mg2+ e pH integram novos mecanismos regulatórios da estrutura e função de peroxirredoxinas mitocondriais de Leishmania contribuindo para a sobrevivência do parasita = Ca2+, Mg2+ and pH integrate novel regulatory mechanisms of structure and function of mitochondrial peroxiredoxins from Leishmania contributing to parasite survival . 2016. Tese (Doutorado) – Universidade Estadual de Campinas, Instituto de Biologia. (12/24134-3)