CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Hospital da Mulher Professor Doutor José Aristodemo Pinotti. Centro de Atenção Integral à Saúde da Mulher (CAISM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
She graduated in Medicine, Faculty of Medical Sciences, State University of Campinas (1983) with specialization (Residency) in Obstetrics and Gynecology (1986 ) from the same institution. She also has the title of Specialist in Gynecology and Obstetrics (TEGO) by the Brazilian Society of Obstetrics Gynecology ( 1993) and the title of Specialist in Mastology (TEMA) by the Brazilian Society of Mastology (2004). She made a Master degree in Obstetrics and Gynecology (1992), a PhD in Obstetrics and Gynecology (1995). She is currently full Professor in Gynecology at the Department of Obstetrics and Gynecology, Faculty of Medical Sciences (FCM ), State University of Campinas (Unicamp). She has experience in research in medicine, with emphasis on tumor biomarkers, ovarian cancer, breast cancer and HPV infection. She publishes regularly taking more than 100 articles indexed in PubMed / Medline . Serves as associate editor in the Brazilian Journal of Gynecology and Obstetrics and the journal BMC Cancer . She is also a reviewer for several national and international journals. She supervises research of undergraduate students, and posgraduated students (master degree and PhD). She coordinates research projects with governamental foundings. (Source: Lattes Curriculum)
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Despite advances in molecular knowledge, breast cancer is still the most commonly diagnosed type of cancer and inducing more deaths in women worldwide, mainly due to the metastatic process and resistance to treatment. The DNA damage response pathway (DDR) is activated in response to genotoxic damage, controlling the cell cycle arrest or activating DNA repair. Studies showed that cancer st…
This project pertains to a line of research on potential clinical, sonographic and biochemical predictors of malignancy in women with adnexal tumors. The objective of the study is to evaluate the accuracy of CA125, HE4 and mesotelin, standing alone or combined with sonographic findings and symptoms to differentiate ovarian tumors in women who underwent a laparotomy due to an adnexal mass.…
(Only some records are available in English at this moment)
Introduction: Once the woman with an adnexal mass undergoes surgery, the histological diagnosis can be given through intraoperative frozen section biopsy or the result of the paraffin analysis is awaited. The purpose of the intraoperative frozen section is to investigate the type and stage of disease and guide the surgeon in the extent of resection, with particular concern for fertility p…
Introduction: Triple negative breast carcinomas (TNBC), although sensitive to neoadjuvant chemotherapy (NACT), have higher rates of early recurrence and worse prognosis when compared to other BC subtypes. They do not express estrogen, progesterone and human epidermal growth factor 2 (HER2) receptors. However, TNBCs include different diseases, with different histologies, tumor microenviron…
Ovarian carcinoma can be recognized and attacked by the immune system, and thus contain a lymphocyte infiltrate. Tumor infiltrating lymphocytes - TILS, are present in the tumor microenvironment. Its presence, type and frequency have been associated with prognosis. Research on the expression of tumor microenvironment immunohistochemical markers in women with ovarian carcinoma may generate …
(Only some records are available in English at this moment)
Natural Killer cells are cytotoxic lymphocytes that are part of the innate immune response against viral infections and neoplasia. Recently, we have demonstrated that it is possible to obtain preparations of effector cells rich in NK cells from patients with ovarian neoplasia, by long-term culture of peripheral blood mononuclear cells (PBMC) in vitro. The effector cells obtained had a sig…
| 11 / 6 | Completed research grants |
| 29 / 15 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 41 / 22 | All research grants and scholarships |
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