CV Lattes
ResearcherID
Secretaria da Saúde (São Paulo - Estado). Hospital das Clínicas da Faculdade de Medicina da USP (HCFMUSP). Instituto do Coração Professor Euryclides de Jesus Zerbini (INCOR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Educação Física from Universidade de São Paulo (1974), master's at Fitness from Universidade de São Paulo (1981) and ph.d. at Fisiologia from University Of Wisconsin Madison (1985). Has experience in Medicine, focusing on Medicine, acting on the following subjects: exercício, treinamento físico, insuficiência cardíaca, pressão arterial and exercise training. (Source: Lattes Curriculum)
| Articles published in Pesquisa FAPESP Magazine about the researcher: |
| The heart's sensor |
| El sensor del corazón |
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| News published in Agência FAPESP Newsletter about the researcher |
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Obesity affects more than 400 million subjects in the world and projections for the next 15 years predict an overall prevalence of up to 20%. In developing countries, such as Brazil a rapid nutritional transition provided by the recent economical growth has led to a unique condition on which the malnourished persist in parallel with an increasing number of obese subjects. It is expected t…
Despite of the uninterrupted development of new medications for the treatment of cancer, the survival rate continues low especially in those patients in the advanced stage of the disease. Recent observations show that new therapeutics increase the susceptibility for cardiovascular diseases, which turns out to be the treatment of cancer even more complex. Cardiac dysfunction due to cardiot…
The School of Physical Education and Sport of the University of São Paulo (EEFE-USP) has been working towards the improvement of research facilities, as it has been demonstrated in the funding provided by Institutional Technical Reserve in the last few years. Once again, we are walking this path to ensure the quality of the activities developed in our laboratories by proposing the acquisi…
Accumulated evidences show that exercise training plays an important role in cardiovascular disease. The present study will focus on the effects that exercise training may have on muscle mechanoreflex and metaboreflex controls of sympathetic nerve activity in patients with heart failure. In addition, we will investigate the cellular mechanisms involved in these controls. At a vascular lev…
(Only some records are available in English at this moment)
Circulating tumor cells (CTCs) are associated with poor prognosis and metastasis. Recent studies show that exercise can be an important adjuvant strategy in the treatment of cancer. It increases cardiorespiratory fitness and muscle strength, improves the inflammatory process and reduces pain and muscle fatigue. However, the effects of exercise on CTCs and survival of tumor cells are unkno…
Doxorubicin (DOX) is a potent antibiotic, used in the cancer treatment. However, this therapeutic strategy provokes side effects, such as cardiotoxicity. Macroscopic disarray and cardiomyocyte death are among the most common cardiac alterations, which have been attributed to reactive oxygen species generation and suppression of important mechanisms of stress-mediated cellular survival res…
The continuous moderate aerobic training (CMT) has been successfully used in reducing the sympathetic nervous activity in patients with heart failure and autonomic changes that seem to be explained, at least in part, by improvement in sensitivity of arterial baroreceptors, peripheral chemoreceptors and (mechano/metaboreceptors) muscle ergoreceptors. The high intensity interval training (H…
(Only some records are available in English at this moment)
The notion that habitual aerobic exercise increases insulin-induced vasodilation is largely founded on rodent studies, hence the urgent need for human studies, especially in patients with type 2 diabetes (T2D). Based on previous data, we hypothesize that this restoration of vascular actions of insulin is associated with a reduction of protein kinase C (PKC) activation and endothelin-1 (ET…
More than two-thirds of women in US are classified as overweight or obese. This scenario represents a growing public health problem even in Brazil. Obesity increases the risk of developing invasive breast cancer (BC). Increased adiposity nourishes an environment propitious for tumor establishment and progression associated with increased hypoxia, desmoplasia and reduced perfusion, contrib…
| 1 / 1 | Ongoing grants |
| 11 / 6 | Completed research grants |
| 8 / 4 | Completed scholarships in Brazil |
| 3 / 2 | Completed scholarships abroad |
| 23 / 13 | All research grants and scholarships |
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