CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Faculdade de Tecnologia (FT) (Institutional affiliation from the last research proposal) Birthplace: Brazil
holds a degree in Biological Sciences from the State University of Campinas (1979), a master's degree (1985) and doctorate (1990) in Genetics and Molecular Biology from the State University of Campinas and "livre docência" in Toxicology from the University of São Paulo (2011). She completed a postdoctoral internship at the National Institute of Environmental Health Sciences (NIEHS) and at the Environmental Protection Agency (EPA) of the United States. She was a visiting professor at the Wilson College of Textiles at North Carolina State University (2018-2019). She is currently a full professor at the Faculty of Technology at UNICAMP and coordinates the Laboratory of Ecotoxicology and Genotoxicity LAEG. She worked for 22 years at the Environmental Agency of State of São Paulo (CETESB). Actively participated in the revision of CONAMA resolution 357/2005 and in the elaboration of CONAMA resolution 396/2008. She also contributed to the revisions of the potability ordinance in Brazil. She was president of the Brazilian Society of Environmental Mutagenesis, Carcinogenesis and Teratogenesis. Member of the editorial board of Environmental Molecular Mutagenesis. Se is a member of the International Initiative on Water Quality - IIWQ Experts Advisory Group of UNESCO-IHP. She has experience in the area of #8203;#8203;Environmental Toxicology, working mainly in the areas of environmental mutagenesis, ecotoxicology, toxicology of dyes of natural and synthetic origin and regulatory toxicology. She is currently developing protocols for evaluating toxicity, genotoxicity and internal doses of chemicals with a new model organism, the marine amphipod of circumtropical distribution, Parhyale hawaiensis. (Source: Lattes Curriculum)
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Parhyale hawaiensis is an epibenthic amphipod that lives in shallow waters and/or intertidal regions and is globally distributed in tropical regions. This amphipod is already a model for embryogenic, genomic, regeneration, and evolutionary development studies; and more recently is being used in ecotoxicological studies. Acute and chronic toxicity, genotoxicity, early molecular biomarkers …
Synthetic dyes and pigments are widely used in the textile industry, and the potential risks of colourants such as azo dyes to human health and the environment are already recognized. Certain natural compounds have a long history as colourants but after the 20th century transition to synthetic dyes, their usage in textile coloration has been minimal. There is a trend in the world to produ…
Effect Directed Analysis (EDA) have been shown the best way to diclose new priority pollutants. Bioassays, like the Salmonella/microsome assay (Ames test), have been used susccessfuly in EDA studies, but with limitations when the samples are not potent enough to be fractionated and re-tested. With the advance of the chemical techniques in the non-target analysis, the ability to identify p…
(Only some records are available in English at this moment)
The textile industry has a strong influence on the world economy, but it is one of the sectors that most cause environmental pollution. This industry releases effluents into the environment containing various toxic chemical compounds, with dyes being one of their main constituents. Dyes can reach the environment directly or through textile fibers, making it important to study their toxic …
Immunotoxicology studies using invertebrate organisms is an expanding field of research, due to the need to develop new methodological approaches that aim to replace tests with vertebrates. These organisms have an innate immune system, which is characterized by hemocytes with essential activities for defending against chemical compounds. The marine amphipod Parhyale hawaiensis has been es…
6PPD-quinone is one of the transformation products of 6PPD, which is an antioxidant widely used in tire rubber. 6PPD-quinone is generated after 6PPD reacts with atmospheric ozone and can concentrate on roads and be leached into water through surface runoff. Studies into the effects of 6PPD-quinone have been carried out since the first evidence that the compound caused acute toxicity to th…
(Only some records are available in English at this moment)
Alizarin dye (1,2-dihydroxyanthraquinone) is an anthraquinone usually extracted from Rubia tinctorum plant. Madder, a dye widely used in textile dyeing and that has mostly alizarin in its composition, can also be extracted from this plant. Thus, alizarin can reach the aquatic ecosystem through the release of effluents from the textile industries. Alizarin presented acute toxicity to the a…
Emodin is an anthraquinone of natural origin that has been shown to be toxic and mutagenic in several biological systems, possibly due to the flatness of its molecule. Mutagenic substances can lead to dysfunction and cell death in somatic cells at the individual level, while in germ cells they can trigger adverse effects at the population level, such as reduced reproduction capacity. Emod…
Marine and freshwater ecosystems are used as the final destination for domestic, industrial and farming effluents. According to Brazilian legislation, effluents should not have the potential to impact the receiving body, both fresh and salt water and to assess this impact, toxicity tests are required. The objective of this work is to test the acute toxicity of urban sewage using different…
(Only some records are available in English at this moment)
Alizarin (1,2-dihydroxyanthraquinone) is an anthraquinone usually extracted from the Rubia tinctorum plant. From this plant it is also possible to extract madder, a dye widely used in fabric dyeing, which has mostly alizarin in its composition. Alizarin can reach the aquatic ecosystem through the discharge of effluents from the textile industry. Studies in the literature have reported acu…
Pesticides are used in large amounts in modern agriculture to secure nutrition and biofuel production. Registration and authorization of pesticides requires that they can be used without harm to the environment and appropriate safety data have to be provided before marketing and application. However, the assessment is based on individual compounds while typically pesticides occur in the e…
Pollution is a big concern these days and among environmental pollutants, genotoxic compounds are very important because they can cause adverse effects in the reproduction, development and growth of the exposed biota. To prevent these damages, it is important to assess the genotoxic potential of environmental samples using effect-based tools. DNA damage can be evaluated by the comet assay…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing grants |
| 14 / 12 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 25 / 23 | Completed scholarships in Brazil |
| 8 / 8 | Completed scholarships abroad |
| 52 / 48 | All research grants and scholarships |
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