graduate at Ciências Biológicas from UNESP - Botucatu (1990), master's at Genética e Melhoramento de Plantas from Universidade de São Paulo (1994) and ph.d. at Genética e melhoramento de plantas from Universidade de São Paulo (1998). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms (Source: Lattes Curriculum)
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The UNIFESP Microbial Interaction Laboratory (LIMic) research group has a line of research that studies the genetic mechanisms that control the response to nutritional stress in fungi, which is essential for pathogenesis. In addition, it is part of this line of research to prospect for new inhibitors that have antifungal potential. Treatment against eukaryotic pathogens is difficult as th…
C. neoformans is an opportunistic fungal pathogen of great medical importance because it affects immunocompromised individuals. Treatment against eukaryotic pathogens is difficult because there are few options of antifungal drugs and low selective toxicity. As a result, there is an effort of the scientific community to better understand the differences between pathogens and hosts in relat…
Metabolic diversity is an important factor during microbial adaptation to different environments. Among metabolic processes, amino acid biosynthesis has been demonstrated to be relevant for survival for many microbial pathogens, whereas the association between pathogenesis and amino acid uptake and recycling are less well-established. Cryptococcus neoformans is an opportunistic fungal pat…
The chemical composition and antimicrobial activity of essential oils obtained from three Brazilian plant species - leaves and branches of Eremanthus erythropappus (Asteraceae), leaves of Plectranthus barbatus, and leaves of P. amboinicus (Lamiaceae) -were determined. Analysis by GC/MS and determination of Kovats indexes both indicated ´-elemene (leaves-42.61% and branches-23.41%) as well…
The yeast Cryptococcus neoformans is an opportunistic fungal pathogen that can cause meningitis and pneumonia in immunocompromised individuals, especially patients with AIDS/HIV, transplanted and undergoing chemotherapy. In general, Invasive Fungal Infections (IFIs) are difficult to treat, because the antifungals used in the clinic, in addition to being scarce, do not have a high selectiv…
Invasive Fungal Infections (IFIs) are caused by opportunistic pathogens like the basidiomycete fungus Cryptococcus neoformans. These infections mainly affect immunocompromised individuals, spreading to several body sites, including the central nervous system, causing fungal meningitis, a disease with a high mortality rate. Cryptococcosis is difficult to treat, because drugs available on t…
(Only some records are available in English at this moment)
Cryptococcus neoformans is considered an opportunistic pathogenic fungus that causesseveral infections in immunocompromised patients and is the etiologic agent of cryptococcalmeningitis. Due to the small number of antifungals used in the clinic and the growingappearance of isolates resistant to therapeutic treatments and pharmacological agents, thesearch for knowledge about the mechanisms…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 6 / 3 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 12 / 6 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 25 / 15 | All research grants and scholarships |
| Associated processes | |
CV Lattes
ORCID