CV Lattes
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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Medicine from Universidade Federal do Rio de Janeiro (1979), Master´s degree in Byophysics from Universidade Federal do Rio de Janeiro (1982), Doctorate in Biological Sciences (Biophysics) from Universidade Federal do Rio de Janeiro (1988) with a training fellowship at Yale University and Post Doctoral training at Albert Ludwigs Universität, Freiburg, Germany. Currentlyan Associate Professor at Ribeirão Preto Medical School of the University of São Paulo. Has experience in Cell and Molecular Biology, focusing on Embryology and Molecular Genetics of Development , working on the genetic, molecular and functional characterization of the IRM protein family of Drosophila and their vertebrate homologues. (Source: Lattes Curriculum)
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The Irre Cell-Recognition Module (IRM) of Drosophila comprises the products of the genes roughest (rst), kin-of-irre (kirre), sticks-and-stones (sns) and hibris (hbs) and form a small subgroup of evolutionarily conserved transmembrane glycoproteins belonging to the immunoglobulin superfamily. IRM molecules normally work cooperatively in a wide variety of developmental processes during an…
The Irre cell-recognition module (IRM) comprises a small group of evolutionarily conserved type I transmembrane glycoproteins belonging to the immunoglobulin superfamily, originally characterized in D. melanogaster, that act in concert and in a partially redundant manner, in a wide range of developmental processes that require cell recognition, adhesion and intercellular signaling. In hu…
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The IRM (Irre Cell Recognition Module) comprises a small, structurally related, and evolutionarily conserved group of cell adhesion molecules from the immunoglobulin superfamily, which act in a coordinated and - in some cases - partially redundant manner, across a wide range of processes during animal development. In Drosophila, mutations affecting IRM function can cause defects in ovaria…
The roughest (rst) gene shows pleiotropic behaviour and its role in several processes during the development of Drosophila melanogaster has been described, such as axonal pathfinding, larval salivary gland histolysis, myoblast fusion during the formation of embryonic musculature and differentiation of pigment cells during compound eye development. The gene encodes a single-pass transmembr…
The roughest (rst) gene has a pleiotropic character, and its involvement is described in several processes of the Drosophila melanogaster development, such as axonal targeting, salivary gland histolysis, embryonic musculature formation and differentiation of pigmentary cells during the development process of the compound eye. The protein encoded by this locus is transmembrane, unipasso, w…
The final architecture of the Drosophila retina is the result of the sequential speciation of different cell types from a previously unpatterned epithelial monolayer, the eye imaginal disc. During the retina development, the repetitive hexagonal units called ommatidia are separated from each other by uncommitted interommatidial cells (IOCs). The sorting of IOCs in to a one single layer su…
| 11 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 7 / 3 | Completed scholarships in Brazil |
| 19 / 8 | All research grants and scholarships |
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