Associate professor at the Physics Institute of São Carlos (IFSC) of the University of São Paulo (USP). He received his PhD in biomolecular physics from the University of São Paulo and the University of Marburg in 2008, and completed two years of postdoctoral work in medicinal chemistry and structural biology at the University of São Paulo. He is a specialist in structure-based drug design and in the integration of computational and experimental methods. His research is focused on the structural elucidation of relevant molecular targets and the application of this knowledge toward the discovery and development of new drugs and agrochemicals for human and plant diseases. He was the coordinator of a Young Research Grant from Serrapilheira Institute, whose scientific approach consists of the use of a variety of advanced methods for agrochemical and drug design. He has published over 110 scientific papers and 8 book chapters. He is the inventor of 3 patents, 2 international in collaboration with life sciences companies. He is associated investigator of the Center for Research and Innovation in Biodiversity and Drugs (CIBFar-CEPID-FAPESP). He was the Chair (2016-2018) and Vice-Chair (2014-2016) of the Medicinal Chemistry Division of the Brazilian Chemical Society. He is an TWAS Young Alumni of The World Academy of Sciences (TWAS), member of the Young Scientist Community of the World Economic Forum (WEF) and Young Scientist of the World Laurate Association (2019-2024). (Source: Lattes Curriculum)
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Infectious diseases have shaped the course of human history and continue to pose significant challenges to global health. They are caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi and are responsible for a significant proportion of deaths worldwide. Malaria is a parasitic infection widespread in tropical and subtropical regions of the world. Due to its hi…
A holobiont is constituted by a host and its whole ecological community of associated microbes. It is a unit of evolution, and the holobiont selection is a major evolutionary force. One feature which it is still poorly addressed is the role of secondary metabolites in microbes-host relationships, as well as in chemically mediated interactions between holobionts (the microbes-host ensemble…
Malaria is a lethal parasitosis, worldwide prevalent, and despite investments in the search for new drugs, a high mortality rate is still observed. In the search for new candidates for antimalarial drug discovery, glycolytic pathway modulation has been explored as target to inhibit parasite development and fight infection. Enolase (Pfeno) is an attractive target of the parasite glycolytic…
Malaria remains a lethal parasitic disease with a global prevalence, and despite extensive efforts to find new drugs, the mortality rate remains high. Given the vast structural diversity and potent biological activities of natural products, they represent attractive candidates for discovering and developing novel therapeutics. Fungi from various sources have been extensively studied for t…
Despite significant advancements in the battle against malaria in recent decades, the emergence of drug resistance in the parasite has posed a major challenge and raised considerable concern. Therefore, the search for new antimalarial drug candidates, preferably with distinct modes of action from existing drugs, is crucial to reduce the likelihood of resistance development. In this regard…
Malaria is an infectious disease caused by protozoa of the genus Plasmodium ssp. Despite significant success in fighting the disease over the past two decades, nearly half of the world's population was at risk of contracting malaria and there were an estimated 241 million cases and 627,000 deaths due to malaria in 2020. In the search for new candidates for antimalarial drugs, the modulati…
(Only some records are available in English at this moment)
Malaria is a deadly parasitic disease with a global prevalence, and despite considerable efforts in the search for new treatments, a high mortality rate still persists. In the search for new antimalarial drugs, targeting the glycolytic pathway has been explored to inhibit parasite development and combat the infection. Among the enzymes in the glycolytic pathway, Plasmodium falciparum pyru…
Malaria is a lethal parasitic disease with worldwide prevalence and despite investments in the search for new drugs, a high mortality rate is observed. The great structural diversity of natural products as well as their potent biological activities makes them attractive molecules for the discovery and development of new drugs. Among the microorganisms, fungi of different origins have been…
This post-doc will work in collaboration with expert scientists from the Medicines for Malaria Venture (MMV, www.mmv.org) and have access to a very well organized framework providing an integrated approach to modern drug discovery. The overall goal with MMV is to deliver a clinical candidate to treat Malaria, as defined by the criteria for an MMV Preclinical candidate. Such a compound sho…
(Only some records are available in English at this moment)
Malaria remains a significant global public health challenge, affecting millions of individuals each year and placing a heavy burden on healthcare systems, especially in regions with high transmission rates. Over the years, the emergence and spread of resistant parasites have posed a serious threat to malaria treatment. This has led to a pressing need for the validation of new molecular t…
Sugarcane derivatives stand out as major contributors to renewable energy sources in bioenergy production. However, the occurrence of severe diseases affects the productivity of sugarcane crops. One such condition is leaf scald disease, which is caused by the gram-negative bacteria Xanthomonas albilineans. Leaf scald disease has a dramatic impact on crop productivity, including reduced yi…
Sugarcane derivatives stand out as major contributors to renewable energy sources in bioenergy production. However, the occurrence of severe diseases affects the productivity of sugarcane crops. One such condition is leaf scald disease, which is caused by the gram-negative bacteria Xanthomonas albilineans. Leaf scald disease has a dramatic impact on crop productivity, including reduced yi…
| 2 / 2 | Ongoing grants |
| 3 / 3 | Completed research grants |
| 5 / 5 | Ongoing scholarships in Brazil |
| 17 / 15 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 30 / 28 | All research grants and scholarships |
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CV Lattes
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