Full Professor in the Department of Pathology at the University of São Paulo (USP) School of Medicine. Professor at the USCS School of Medicine and Director of the Tropical Medicine Institute at USP from 2015 to 2019. She is a member of the Brazilian Academy of Sciences and has been awarded the Armando Salles de Oliveira Medal and the 2026 TWAS Prize in Medical Health Sciences. She serves as the principal investigator for the NIH programs Recipient Epidemiology and Donor Evaluation Study-IV Pediatric and the São Paulo-Minas Gerais Neglected Tropical Disease Research Center for Biomarker Discovery. Main research areas: transfusion safety, HIV, Chagas disease, emerging viruses, and sickle cell anemia. (Source: Lattes Curriculum)
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Loop-mediated isothermal amplification (LAMP) is a low-cost DNA amplification technique that is useful for low- and middle-income countries for the screening of infectious diseases. Current methods to detect the amplification assay are based on the analysis of samples using benchtop analysis tools for fluorogenic marker intensity and requires an expert to operate the device and analyze th…
COVID-19 is an acuterespiratory disease caused by the coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).In Brazil, it is a concern due to its impact on health care structures and its current mortality rate (especially in age groups above 60 years). Exponential growth of cases is expected and assessment of frequency rates such as morbidity, mortality, lethality…
Recently Brazil has been affected by unexpected arbovirus epidemics of Zika, Chikungunya, dengue and Yellow fever viruses. The huge economic burden of Zika (R$ 1 billion) and the widespread presence of mosquito vectors in Brazil highlights the need for accurate predictions of disease spread, particularly in large, densely populated regions. This UK-Brazil Partnership will enhance and expa…
(Only some records are available in English at this moment)
The Covid-19 pandemic has raised concerns regarding the use and development of screening and diagnostic models that are low-cost, highly sensitive, and widely applicable. The widespread dissemination of this virus makes it difficult to control, making mass testing of individuals an efficient measure for screening and controlling its spread. However, the high cost of tests, coupled with th…
Chikungunya fever (CF) remains an important public health problem in Brazil. Although most patients have symptoms resolution in the acute phase of the disease, 25-50% of cases progress to post-Chikungunya Chronic Inflammatory Joint Disease (pCHIKV-CIJD, post-Chikungunya Chronic Inflammatory Joint Disease), impacting directly on the quality of life of these patients. Despite causing epidem…
The availability of viral genome sequencing techniques and projections by means of mathematical, statistical, and computational models allow tracking the emergence and spread of infectious diseases on a local and global scale. Since the first confirmed case of SARS-CoV-2 infection, these techniques and analyses are responsible for an active and continuous monitoring of the epidemiological…
(Only some records are available in English at this moment)
Recently, Brazil has been affected by unexpected and explosive epidemics of insect- transmitted viruses (arboviruses), most notably Zika, chikungunya, dengue, and yellow fever viruses. Those viruses have brought much concern in public health, and due to genetic changes, host and vector population dynamics and environmental factors, in addition to its capacity for adaptation are emerging a…
Plasma leakage is one of the main complications of dengue virus (DENV) infections and is directly related to disease severity. Dengue pathogenesis is complex and multifactorial, involving both viral and host factors. We have recently showed that contact of endothelial cells with serum from DENV-infected patients with leakage disrupts endothelial barrier function, indicated by reduction o…
The research of pathogens in blood donors can contribute significantly to improve the quality of blood products and the safety concern. Currently, blood banks (in Brazil or around the globe?), perform serological screening only for seven agents (Hepatitis, HTLV, HIV, Syphilis and Chagas). However, many other agents known or yet unidentified might be are present in samples from donors. The…
| 26 / 19 | Completed research grants |
| 37 / 30 | Completed scholarships in Brazil |
| 3 / 3 | Completed scholarships abroad |
| 66 / 52 | All research grants and scholarships |
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