José Luiz Proença Módena
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
José Luiz Proença Módena in research grants and scholarships supported by FAPESP.
- Characterization of intrinsic risk factors and the development of new diagnostic and treatment alternatives for COVID-19, AP.R
Abstract
The arrival of SARS-CoV-2 in Brazil in March 2020 negatively impacted the economy, generated panic in the population and disrupted our country's public and private health systems. It is evident that there is a need for rapid diagnostic / prognostic methods and therapeutic alternatives to deal with this pandemic in our country. Thus, this multidisciplinary project, which involves researc...
- Pathogenesis and neurovirulence of emerging viruses in Brazil, AP.JP
Abstract
Emerging viruses are agents associated with a new or a previous low-prevalent disease in a specific geographic region that significantly increased their incidence that area. Among the emerging viruses in Brazil is possible to highlight: Zika (ZIKV), Oropouche (OROV), Chikungunya (CHIKV), Mayaro (MAYV) and probably La Crosse (LACV), Iquitos virus (IQTV), Japanese Encephalitis (JEV), Sain...
- The role of the presence of IRF-5 in dendritic cells, macrophages and b lymphocytes to control infection by the Oropouche Virus in murine model, BP.IC
Abstract
Emerging viruses can cause great impacts on a susceptible population. A example of this are virus transmitted by arthropods which are widely spread in wild and urban areas, such as Oropouche Vírus (OROV). This is an emergent arbovirus that can be transmitted in urban environmental by the bite of Culicoides paraensis, a hematophagous fly that circulates in the North and Northeast of Braz...
- The role of activation and metabolic imbalance of dendritic cells for Chikungunya Virus pathogenesis, BP.DR
Abstract
The Chikungunya virus (CHIKV) is an emerging arbovirus present in tropical and subtropical regions transmitted by the arthropod vector A. aegypti. Although CHIKV infection may be asymptomatic, it usually leads to the development of an acute febrile illness, joint pain and swelling. One of the major complications associated with CHIKV are chronic manifestations such as arthralgia and art...
- The role of innate recognition pathways and type I and III interferons in the rupture of the placental barrier after OROV infection, BP.DR
Abstract
The Oropouche Virus (OROV) is an arbovirus with potential to cause epidemics in the most populated regions of Brazil. Individuals infected with OROV develop a febrile illness, which can progress to neurological and hemorrhagic complications. Furthermore, an increased incidence of abortion was reported during major OROV epidemics. However, the teratogenic potential of OROV and the pathog...
(Only some records are available in English at this moment)
- Arbovirus detection and characterization in Campinas, BP.TT
- The role of adaptive immune response in neuroinvasion by Oropouche and Zika virus, BP.MS
Abstract
Emerging viruses, mainly those transmitted by arthropods widely spread in urban areas, are a great concern for public health worldwide. Zika virus (ZIKV) is an emerging virus in Brazil often associated with fever-rash illness and some serious complications, such as a Guillain-Barré like syndrome and congenital malformations, including microcephaly. Oropouche virus (OROV) is another emer...
| 2 / 2 | Ongoing research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 4 / 2 | Completed scholarships in Brazil |
| 10 / 8 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 8 |
| Citations | 77 |
| Cit./Article | 9.6 |
| Data from Web of Science | |
VENCESLAU, EMANUELLA MENESES; SIQUEIRA GUIDA, JOSE PAULO; NOBREGA, GUILHERME DE MORAES; SAMOGIM, ANA PAULA; PARISE, PIERINA LORENCINI; JAPECANGA, RODOLFO ROSA; DE TOLEDO-TEIXEIRA, DANIEL AUGUSTO; FORATO, JULIA; ANTOLINI-TAVARES, ARTHUR; SOUZA, ARETHUSA; et al. Adequate Placental Sampling for the Diagnosis and Characterization of Placental Infection by Zika Virus. FRONTIERS IN MICROBIOLOGY, v. 11, FEB 21 2020. Web of Science Citations: 0. (17/26908-0, 16/00194-8, 17/02402-0)
MOTTIN, MELINA; BORBA, JOYCE V. V. B.; BRAGA, RODOLPHO C.; TORRES, PEDRO H. M.; MARTINI, MATHEUS C.; PROENCA-MODENA, JOSE LUIZ; JUDICE, CARLA C.; COSTA, FABIO T. M.; EKINS, SEAN; PERRYMAN, ALEXANDER L.; et al. The A-Z of Zika drug discovery. DRUG DISCOVERY TODAY, v. 23, n. 11, p. 1833-1847, NOV 2018. Web of Science Citations: 10. (17/02353-9, 16/13805-5, 16/00194-8, 12/16525-2)
KAM, YIU-WING; LEITE, JULIANA ALMEIDA; LUM, FOK-MOON; TAN, JESLIN J. L.; LEE, BERNETT; JUDICE, CARLA C.; DE TOLEDO TEIXEIRA, DANIEL AUGUSTO; ANDREATA-SANTOS, ROBERT; VINOLO, MARCO A.; ANGERAMI, RODRIGO; et al. Specific Biomarkers Associated With Neurological Complications and Congenital Central Nervous System Abnormalities From Zika Virus-Infected Patients in Brazil. Journal of Infectious Diseases, v. 216, n. 2, p. 172-181, JUL 15 2017. Web of Science Citations: 26. (16/00194-8)
PROENCA-MODENA, JOSE LUIZ; GAGLIARDI, TALITA BIANCA; DE PAULA, FLAVIA ESCREMIM; IWAMOTO, MARISA AKIKO; CRIADO, MIRIA FERREIRA; CAMARA, ATAIDE A.; ACRANI, GUSTAVO OLSZANSKI; LEITE CINTRA, OTAVIO AUGUSTO; CERVI, MARIA CELIA; DE PAULA ARRUDA, LUISA KARLA; et al. Detection of Human Bocavirus mRNA in Respiratory Secretions Correlates with High Viral Load and Concurrent Diarrhea. PLoS One, v. 6, n. 6, JUN 20 2011. Web of Science Citations: 27. (09/51818-8, 08/50617-6)
JUDICE, CARLA CRISTINA; TAN, JESLIN J. L.; PARISE, PIERINA LORENCINI; KAM, YIU-WING; MILANEZ, GUILHERME PAIER; LEITE, JULIANA ALMEIDA; CASERTA, LEONARDO CARDIA; ARNS, CLARICE WEIS; RESENDE, MARIANGELA RIBEIRO; ANGERAMI, RODRIGO; et al. Efficient detection of Zika virus RNA in patients' blood from the 2016 outbreak in Campinas, Brazil. SCIENTIFIC REPORTS, v. 8, MAR 5 2018. Web of Science Citations: 6. (16/00194-8)
PROENCA-MODENA, JOSE LUIZ; CARDOSO, RICARDO DE SOUZA; CRIADO, MIRIA FERREIRA; MILANEZ, GUILHERME PAIER; DE SOUZA, WILLIAM MARCIEL; PARISE, PIERINA LORENCINI; BERTOL, JESSICA WILDGRUBE; SANTOS DE JESUS, BRUNA LAIS; MOREIRA PRATES, MIRELA CRISTINA; SILVA, MARIA LUCIA; et al. Human adenovirus replication and persistence in hypertrophic adenoids and palatine tonsils in children. Journal of Medical Virology, v. 91, n. 7, p. 1250-1262, JUL 2019. Web of Science Citations: 2. (09/51818-8, 16/00194-8)
PROENCA-MODENA, JOSE LUIZ; MILANEZ, GUILHERME PAIER; COSTA, MARIA LAURA; JUDICE, CARLA C.; MARANHAO COSTA, FABIO TRINDADE. Zika virus: lessons learned in Brazil. Microbes and Infection, v. 20, n. 11-12, p. 661-669, DEC 2018. Web of Science Citations: 5. (16/00194-8)
KAM, YIU-WING; LEITE, JULIANA ALMEIDA; AMRUN, SITI NAQIAH; LUM, FOK-MOON; YEE, WEARN-XIN; ABU BAKAR, FARHANA; ENG, KAI ER; LYE, DAVID C.; LEO, YEE-SIN; CHONG, CHIA-YIN; et al. ZIKV-Specific NS1 Epitopes as Serological Markers of Acute Zika Virus Infection. Journal of Infectious Diseases, v. 220, n. 2, p. 203-212, JUL 15 2019. Web of Science Citations: 1. (16/00194-8, 13/25807-4)