Professor of the Faculty of Medicine of the University of São Paulo. Degree in Biological Sciences. master's degree and a doctorate in science from the University of São Paulo. He took a research internship at Harvard Medical School in Boston. She is currently a research scientist at the medical research laboratory of the urology discipline at the University of São Paulo. Has experience in the field of Cancer, molecular biology, Genetics and proteomics. (Source: Lattes Curriculum)
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Bladder Cancer (BC) is the tenth most common type of cancer, responsible for about 5% of all new cancer cases. It is a disease with important morbidity and mortality, and its prognostic is directly related to tumor staging. When the disease is restricted to the superficial urothelial layer of the bladder wall (pTa and pT1), the selected treatment is based on the preservation of the bladde…
Castration-resistant metastatic prostate cancer (CRPC) is an incurable disease, a large number of studies have been looking for therapeutic alternatives based on the molecular pathways that act in this phase of the neoplasia. Alterations in the androgen receptor occur frequently in the progression of this neoplasia and the androgen receptor cofactors appear as attractive molecules, since …
Prostate cancer (PC) corresponds to about 10% of all cancers, being considered the sixth most common neoplasm in the world. Due to its high prevalence, it represents an important health problem, with a strong economic impact if we consider the tracing, diagnosis, treatment and mortality due to the disease. The treatments are done according to the patient's diagnosis. In cases of high risk…
The proposed study is to analyze the expression profile of microRNAs miR-221, miR-222, miR-23b and miR27b in tissue samples from patients with prostate cancer (CaP) hormone-sensitive and hormone-resistant and also assess the roles of microRNAs and their antagomirs in CaP cell lines LNCaP and PC-3 that will suffer or no exposure to the hormone, and to evaluate the role of these microRNAs i…
(Only some records are available in English at this moment)
Prostate cancer (PCa) is a public health issue and is considered the second most frequent type of tumor in the male population worldwide. According to INCA, in 2020, the PCa was responsible for 358,301 deaths. Screening is done preventively through PSA measurement, and diagnosis is made by biopsy. The prognosis is based on PSA dosage, pathological stage, tumor volume, and histological gr…
Prostate Cancer (PCa) is characterized by slow growth and represents a type of androgen dependent neoplasia. The Androgen Receptor (AR) plays a key ro le in prostate carcinogenesis and metastasis. Thus, Androgen Deprivation Therapies (ADT) are often used to treat PCa. However, at the time when PCa acquired castration-resistant phenotype (CPRC), ADT is no longer effective. In fact, it is n…
Renal Cell Carcinoma (RCC) is a malignant, chemotherapy-resistant neoplasm that originates in the proximal contorted tubule lining of nephrons. The disease presents approximately 4% of malignancies in adults and was ranked in 2018 as the sixth deadliest cancer worldwide. RCC can be classified according to distinct genetic, molecular, and morphological features and is composed of different…
Bladder cancer is the most common cancer that affects the urinary system in the United States, responsible for thousands of deaths in both men and women. In Brazil alone, according to the Instituto Nacional de Câncer (Inca), 10,640 new cases were predicted in the year 2020. Thus, the search for new treatment methods to combat the disease, especially regarding muscle-invasive carcinoma, si…
Peyronies disease consists of the formation of fibrosis in the tunica albuginea of thecorpus cavernosum of the penis, which can be accompanied by pain, erectiledysfunction, and penile deformation. Its etiology is not fully understood in literature,however, it is believed that the formation of fibrous plaque is caused after recurrentmicrotrauma in the penis during the life of men with a pr…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 4 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 15 / 15 | Completed scholarships in Brazil |
| 22 / 22 | All research grants and scholarships |
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CV Lattes
ORCID