graduation at Ciências Biomédicas from Universidade Estadual Paulista Júlio de Mesquita Filho (2013), master's at Pathological Anatomy and Clinical Pathology from Universidade Estadual Paulista Júlio de Mesquita Filho (2016) and doctorate at Pathological Anatomy and Clinical Pathology from Universidade Estadual Paulista Júlio de Mesquita Filho (2020). Has experience in Morphology, focusing on Histology (Source: Lattes Curriculum)
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The metabolic-associated fatty liver disease (MAFLD) is closely associated with diabetes and obesity, affecting 25% of the global population. MAFLD is also related to the high intake of saturated fatty acids and simple carbohydrates. MAFLD pathogenesis involves an imbalance in hepatic lipid metabolism, increased inflammation, and oxidative stress, that is associated with deregulation of S…
Non-alcoholic fatty liver disease (NAFLD), and its most advanced stage, the non-alcoholic steatohepatitis (NASH) affect 25% and 5% of the world's population, respectively. The NAFLD/NASH are complex and multifactorial conditions involving genetic, epigenetic and environmental risk factors, as the consumption of a saturated fat- and carbohydrate-rich diet. NASH development involves molecul…
Recently, hepatic fibrosis and carcinogenesis have been linked to altered expression of several miRNAs. In contrast, studies indicate that coffee drinking is associated with a 40% lower risk of developing fibrosis or liver cancer. Thus, the present project will evaluate whether caffeine alone or associated with trigoneline and/or chlorogenic acid (CGA): (A) attenuates fibrosis-associated …
Hepatocellular Carcinoma (HCC) represents approximately 6% of all incident cases of cancer and it is the third leading cause of cancer death globally. The development of this malignancy involves great complexity in its pathogenesis and highlights the involvement of metals including iron, zinc and copper. Zinc is a metal that, due the diversity of roles it plays in the body has been the su…
Exposure in utero to xenoestrogens can increase the risk of development of hormone-related cancers in adulthood. Bisphenol A (BPA), a component of epoxy resins and polycarbonate plastics, considered to be a hormonally active chemical and endocrine disruptor, has been investigated for its potential to cause adverse effects on human health. The aims of the current study are: 1) evaluate whe…
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CV Lattes
ORCID