CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Associate Professor at the Faculty of Pharmaceutical Sciences of the São Paulo State University "Júlio de Mesquita Filho" (UNESP) in Araraquara and CNPq Pq2 researcher. Holds a degree in Pharmaceutical Biochemistry from the University of Ribeirão Preto (1992), a master's and doctorate from the Postgraduate Program in Biotechnology at the Institute of Chemistry of the São Paulo State University "Júlio de Mesquita Filho" (UNESP) (2000/2004), and a postdoctoral degree from the Clinical Mycology Laboratory of the Faculty of Pharmaceutical Sciences of UNESP in Araraquara. Teaches in the Pharmacy and Bioprocess and Biotechnology Engineering courses at the Faculty of Pharmaceutical Sciences of UNESP in Araraquara and is accredited in the Postgraduate Program in Biosciences and Biotechnology Applied to Pharmacy and in the Professional Master's Program in Biomaterials and Bioprocess Engineering at FCF UNESP. She completed internships at various institutions, both national and international. She was Vice-Director of the Faculty of Pharmaceutical Sciences from 2017 to 2020 and supervisor of the Auxiliary Unit of the Community Service Center of FCF UNESP in Araraquara from 2020 to 2024. She was vice-coordinator of the Postgraduate Program in Biosciences and Biotechnology Applied to Pharmacy at the Faculty of Pharmaceutical Sciences of UNESP. She has experience in the field of pharmacy, with an emphasis on mycology/microbiology, molecular biology and cell biology, mainly working on the following topics: fungus-host interaction, bioprospecting of substances with antimicrobial activity, pathogenesis and resistance mechanisms of mono- and multi-species biofilms, and alternative methods to animal experimentation. She has supervised master's, doctoral and undergraduate research students and supervised postdoctoral internships. She has given lectures, conferences, and participated in roundtables at national and international events. She has coordinated projects funded by FAPESP and CNPq, and collaborated on projects funded by FINEP and INCT. Currently, she coordinates research projects funded by FAPESP and CNPq focusing on the development of alternative models of 3D human cultures and physiological human tissues for the study of fungal infections and therapeutic targets using integrative omics approaches (proteomics, genomics, transcriptomics, and miRNAs). She maintains technical and scientific collaborations with researchers working in the areas of mycology and molecular and cellular biology at international institutions (Universidad Antioquia, Colombia; Universidad Nacional de México, UNAM, and La Sapienza University of Rome), national institutions (USP), and UNESP. She is currently the coordinator of the Graduate Program in Biosciences and Biotechnology Applied to Pharmacy at the FCF of UNESP (CAPES concept 7) and president of the Advisory Committee of the Vice-Rectorate for Graduate Studies at UNESP. He is a member of the Central Postgraduate Chamber CCPG and a member of the Council for Teaching, Research and University Extension CEPE at UNESP. (Source: Lattes Curriculum)
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In recent years, pulmonary fungal infections and invasive fungal infections (IFIs) have become increasingly prevalent due to the rising number of immunocompromised patients, such as those with Acquired Immunodeficiency Syndrome (AIDS), malignancies, or undergoing organ transplants. In this context, Histoplasma capsulatum and Cryptococcus spp. have recently been classified as fungi of high…
Histoplasma capsulatum var capsulatum is the dimorphic fungus that causes histoplasmosis, a lung infection that can spread to other organs, causing severe forms of the disease. Histoplasmosis is the fourth mycosis that most affects people annually and is distributed worldwide, being considered an Invasive Fungal Infection (IFI) and classified as of high global relevance by the WHO in 2022…
Histoplasma capsulatum variety capsulatum is a fungal pathogen which causes histoplasmosis that occurs as a result of inhalation of microconidea from mycelial phase, primarily affecting the lung which occurs the yeast differentiation, inducing a pulmonary infection and dissemination to other organs. Recently, a correlation between the H. capsulatum infection mode, and the formation of bio…
Histoplasma capsulatum var. capsulatum is a dimorphic fungus that causes histoplasmosis, a respiratory and systemic mycosis. The development of disease depends on the ability of Histoplasma yeast to survive and replicate within alveolar macrophages. In this context, it is known that adherence to host cells is the first step in the colonization and is essential for the establishment of inf…
Histoplasmosis is an invasive fungal infection (IFI) of great global importance caused by the dimorphic fungus Histoplasma capsulatum. According to the World Health Organization, in the Americas, histoplasmosis causes more deaths among individuals with HIV/AIDS than tuberculosis, with 500,000 new cases annually. Moreover, in endemic areas, the incidence of histoplasmosis in individuals wi…
Cryptococcosis is a systemic infection caused by the encapsulated yeasts Cryptococcus neoformans, which primarily affects immunocompromised individuals, and C. gattii, which mainly impacts immunocompetent individuals. The infection typically begins with the inhalation of these yeasts or spores from their teleomorphic phase, specifically Filobasidiella neoformans and Filobasidiella bacilli…
Cryptococcus neoformans and Cryptococcus gattii are the encapsulated yeasts that cause cryptococcosis. Cryptococcosis is a systemic fungal disease characterized by affecting immunocompromised (mainly C. neoformans) and immunocompetent (mainly C. gattii) individuals, affecting the lower respiratory tract and often later, the central nervous system. Antifungal treatment is aggressive, toxic…
(Only some records are available in English at this moment)
Cryptococcus neoformans and Cryptococcus gattii are the encapsulated yeasts that cause cryptococcosis. Cryptococcosis is a systemic fungal disease clinically characterized by affecting immunocompromised (C.neoformans) and healthy (C.gattii) individuals, affecting the lower respiratory tract and subsequently the central nervous system (CNS). Antifungal treatment is aggressive, toxic, and c…
Cryptococcosis is a serious fungal infectious disease that is widespread and opportunistic, with significant public health implications, affecting both immunocompromised and immunocompetent individuals. The main causative agents are Cryptococcus neoformans and Cryptococcus gattii, which have ecological niches in pigeon droppings and decomposing tree matter, leading to their continuous dis…
Histoplasmosis, an Invasive Fungal Infection (IFI), is caused by the dimorphic fungus Histoplasma capsulatum, which has a worldwide distribution. It is the fourth IFI with the highest number of annual cases, reaching more than 600 thousand people every year. In the last two decades, IFIs have increased worldwide and the number of patients at risk has grown dramatically. Recently, a correl…
(Only some records are available in English at this moment)