CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Graduated in Chemical Engineering from Universidade Estadual de Campinas (2000) and Ph.D. in Chemical Engineering from Universidade Estadual de Campinas (2007). Has experience in Proteomics, Peptidomics and Mass Spectrometry. Since 2014 is Assistant Professor at EPM/UNIFESP. (Source: Lattes Curriculum)
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Venomous animals are amongst the most successful animals on Earth's evolutionary history. One of the important factors for their success is the production of venoms, used to subdue prey and as protection against possible predators. Most active toxins are proteins and peptides, elaborated and refined over millions of years of evolution. Venom toxins have served as leads for molecules with …
The diversity of biological activities found in spider secretions as venom and hemolymph have motivated several research groups to search for molecules with potential therapeutic use, which results in an increasing number of toxins isolated and sequenced over the years. But despite advances, the number of spider peptides isolated and characterized is estimated to be only 0.01% of all poss…
The snake Bothrops atrox is known as one of the most lethal to humans in South America. It can be found across the north of the South American continent and east of the Andes. Most of the active biological components of its venom are proteins and peptides, elaborated and refined over millions of years of evolution. Venom toxins have been sources of inspiration for drug research and have b…
Represented by more than 46,000 species and 4,029 genera, the order Araneae established its evolutionary success, among other reasons, due to the toxic properties of their venoms, enabling the species to defend against predators and to subdue preys. Venomics studies on spiders have been growing over the last years, since proteins and peptides make up most of the venom active molecules. Th…
The genus of snakes Naja, also known by the popular name "cobra-de-capelo" is characteristic for aggregating venomous and very aggressive animals, counting approximately 29 species. Among them is the Naja kaouthia, also known as monocle snake or monocle. Venomous snakes use venoms to subdue prey and as protection against predators. Venoms are composed of biologically active peptidic and p…
(Only some records are available in English at this moment)
| 4 / 3 | Completed research grants |
| 7 / 5 | Completed scholarships in Brazil |
| 11 / 8 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 28 |
| Citations | 100 |
| Cit./Article | 3.6 |
| Data from Web of Science | |
ABREU, THIAGO F.; SUMITOMO, BIANCA N.; NISHIYAMA, JR., MILTON Y.; OLIVEIRA, URSULA C.; SOUZA, GUSTAVO H. M. F.; KITANO, EDUARDO S.; ZELANIS, ANDRE; SERRANO, SOLANGE M. T.; JUNQUEIRA-DE-AZEVEDO, INACIO; SILVA, JR., PEDRO I.; et al. Peptidomics of Acanthoscurria gomesiana spider venom reveals new toxins with potential antimicrobial activity. JOURNAL OF PROTEOMICS, v. 151, n. SI, p. 232-242, JAN 16 2017. Web of Science Citations: 8. (12/19321-9)
TASHIMA, ALEXANDRE K.; FRICKER, LLOYD D.. Quantitative Peptidomics with Five-plex Reductive Methylation labels. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, v. 29, n. 5, p. 866-878, MAY 2018. Web of Science Citations: 0. (12/19321-9)
DASGUPTA, SAYANI; FISHMAN, MICHAEL A.; CASTRO, LEANDRO M.; TASHIMA, ALEXANDRE K.; FERRO, EMER S.; FRICKER, LLOYD D.. Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells. BIOMOLECULES, v. 9, n. 6, JUN 2019. Web of Science Citations: 1. (16/04000-3, 17/20106-9)
JOCELINO GOMES DE LACERDA, JOSE THALLES; RODRIGUES E LACERDA, RODRIGO; ASSUNCAO, NILSON ANTONIO; TASHIMA, ALEXANDRE KEIJI; JULIANO, MARIA APARECIDA; DOS SANTOS, JR., GILBERTO ALVES; DE SOUZA, MILENY DOS SANTOS; BATISTA, JACINTO DE LUNA; ROSSI, CARLOS EDUARDO; DE ALMEIDA GADELHA, CARLOS ALBERTO; et al. New insights into lectin from Abelmoschus esculentus seeds as a Kunitz-type inhibitor and its toxic effects on Ceratitis capitata and root-knot nematodes Meloidogyne spp.. Process Biochemistry, v. 63, p. 96-104, DEC 2017. Web of Science Citations: 0. (12/19321-9, 12/02514-9, 12/50191-4)
ZELANIS, ANDRE; SILVA, DEBORA A.; KITANO, EDUARDO S.; LIBERATO, TARCISIO; FUKUSHIMA, ISABELLA; SERRANO, SOLANGE M. T.; TASHIMA, ALEXANDRE K.. A first step towards building spectral libraries as complementary tools for snake venom proteome/peptidome studies. Comparative Biochemistry and Physiology D-Genomics & Proteomics, v. 31, SEP 2019. Web of Science Citations: 0. (13/14651-3, 14/06579-3, 17/20106-9, 13/07467-1, 17/07897-7, 13/13548-4)
HATAKEYAMA, DANIELA MIKI; TASIMA, LIDIA JORGE; BRAVO-TOBAR, CESAR ADOLFO; SERINO-SILVA, CAROLINE; TASHIMA, ALEXANDRE KEIJI; BITTENCOURT RODRIGUES, CAROLINE FABRI; AGUIAR, WESLEI DA SILVA; GALIZIO, NATHALIA DA COSTA; VENANCIO DE LIMA, EDUARDO OLIVEIRA; KAVAZOI, VICTOR KOITI; et al. Venom complexity of Bothrops atrox (common lancehead) siblings. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 26, OCT 12 2020. Web of Science Citations: 0. (17/16908-2, 18/25786-0, 17/01890-0, 17/20106-9)
AGUIAR, WESLEI DA SILVA; GALIZIO, NATHALIA DA COSTA; SERINO-SILVA, CAROLINE; SANT'ANNA, SAVIO STEFANINI; GREGO, KATHLEEN FERNANDES; TASHIMA, ALEXANDRE KEIJI; NISHIDUKA, ERIKA SAYURI; DE MORAIS-ZANI, KAREN; TANAKA-AZEVEDO, ANITA MITICO. Comparative compositional and functional analyses of Bothrops moojeni specimens reveal several individual variations. PLoS One, v. 14, n. 9, SEP 12 2019. Web of Science Citations: 0. (17/01890-0, 17/16908-2, 14/11108-0, 17/20106-9, 18/20651-0, 18/14724-4, 18/25786-0)
FRITZ, RANI; MUKHERJEE, AMARNATH; ZAGHI, SAHAR; AGALLIU, ILIR; JINDAL, SANGITA; TASHIMA, ALEXANDRE K.; FRICKER, LLOYD D.; DAVIES, KELVIN P.. Identification and characterization of RSIY-11, a novel seminal peptide derived from semenogelin-1, which acts as a neutral endopeptidase inhibitor modulating sperm motility. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, v. 36, n. 9, p. 1891-1900, SEP 2019. Web of Science Citations: 0. (17/20106-9)
LÍDIA J. TASIMA; CAROLINE SERINO-SILVA; DANIELA M. HATAKEYAMA; ERIKA S. NISHIDUKA; ALEXANDRE K. TASHIMA; SÁVIO S. SANT’ANNA; KATHLEEN F. GREGO; KAREN DE MORAIS-ZANI; ANITA M. TANAKA-AZEVEDO. Crotamine in Crotalus durissus: distribution according to subspecies and geographic origin, in captivity or nature. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 26, p. -, 2020. Web of Science Citations: 0. (17/20106-9, 16/03311-5, 14/11108-0, 17/16908-2, 17/01890-0)
ADRIANA SIMIZO; EDUARDO S. KITANO; SÁVIO S. SANT’ANNA; KATHLEEN FERNANDES GREGO; ANITA MITICO TANAKA-AZEVEDO; ALEXANDRE K. TASHIMA. Comparative gender peptidomics of Bothrops atrox venoms: are there differences between them?. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 26, p. -, 2020. Web of Science Citations: 0. (17/21052-0, 18/25786-0, 19/03502-3, 17/20106-9)
CHAVES, ALISON F. A.; CASTILHO, DANIELE G.; NAVARRO, MARINA V.; OLIVEIRA, ANA K.; SERRANO, SOLANGE M. T.; TASHIMA, ALEXANDRE K.; BATISTA, WAGNER L.. Phosphosite-specific regulation of the oxidative-stress response of Paracoccidioides brasiliensis: a shotgun phosphoproteomic analysis. Microbes and Infection, v. 19, n. 1, p. 34-46, JAN 2017. Web of Science Citations: 3. (11/14392-2, 14/13961-1, 12/19321-9, 13/07467-1, 12/17530-0)
DASGUPTA, SAYANI; FISHMAN, MICHAEL A.; MAHALLATI, HANA; CASTRO, LEANDRO M.; TASHIMA, ALEXANDRE K.; FERRO, EMER S.; FRICKER, LLOYD D.. Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington's Disease. PLoS One, v. 10, n. 12, DEC 21 2015. Web of Science Citations: 8. (12/19321-9)
CASTILHO, DANIELE G.; CHAVES, ALISON F. A.; XANDER, PATRICIA; ZELANIS, ANDRE; KITANO, EDUARDO S.; SERRANO, SOLANGE M. T.; TASHIMA, ALEXANDRE K.; BATISTA, WAGNER L.. Exploring Potential Virulence Regulators in Paracoccidioides brasiliensis Isolates of Varying Virulence through Quantitative Proteomics. JOURNAL OF PROTEOME RESEARCH, v. 13, n. 10, p. 4259-4271, 2014. Web of Science Citations: 7. (11/14392-2, 12/19321-9)
TASHIMA, ALEXANDRE K.; ZELANIS, ANDRE; KITANO, EDUARDO S.; IANZER, DANIELLE; MELO, ROBSON L.; RIOLI, VANESSA; SANT'ANNA, SAVIO S.; SCHENBERG, ANA C. G.; CAMARGO, ANTONIO C. M.; SERRANO, SOLANGE M. T.. Peptidomics of Three Bothrops Snake Venoms: Insights Into the Molecular Diversification of Proteomes and Peptidomes. MOLECULAR & CELLULAR PROTEOMICS, v. 11, n. 11, p. 1245-1262, NOV 2012. Web of Science Citations: 47. (11/10468-4, 98/14307-9)
SERINO-SILVA, CAROLINE; MORAIS-ZANI, KAREN; TOYAMA, MARCOS HIKARI; TOYAMA, DANIELA DE OLIVEIRA; GAETA, HENRIQUE HESSE; BITTENCOURT RODRIGUES, CAROLINE FABRI; AGUIAR, WESLEI DA SILVA; TASHIMA, ALEXANDRE KEIJI; GREGO, KATHLEEN FERNANDES; TANAKA-AZEVEDO, ANITA MITICO. Purification and characterization of the first gamma-phospholipase inhibitor (gamma PLI) from Bothrops jararaca snake serum. PLoS One, v. 13, n. 3, MAR 5 2018. Web of Science Citations: 1. (13/05357-4, 17/16908-2, 12/19321-9, 14/11108-0, 17/01890-0, 13/12826-0)
FRICKER, LLOYD D.; TASHIMA, ALEXANDRE K.; FAKIRA, AMANDA K.; HOCHGESCHWENDER, UTE; WETSEL, WILLIAM C.; DEVI, LAKSHMI A.. Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary. Cell Chemical Biology, v. 28, n. 1, p. 105+, JAN 21 2021. Web of Science Citations: 0. (17/20106-9)
PEDROSO, AMANDA P.; SOUZA, ADRIANA P.; DORNELLAS, ANA P. S.; OYAMA, LILA M.; NASCIMENTO, CLAUDIA M. O.; SANTOS, GIANNI M. S.; ROSA, JOSE C.; BERTOLLA, RICARDO P.; KLA-WITTER, JELENA; CHRISTIANS, UWE; et al. Intrauterine Growth Restriction Programs the Hypothalamus of Adult Male Rats: Integrated Analysis of Proteomic and Metabolomic Data. JOURNAL OF PROTEOME RESEARCH, v. 16, n. 4, p. 1515-1525, APR 2017. Web of Science Citations: 9. (12/19321-9, 10/20268-0)
MORGON, ADRIANO M.; BELISARIO-FERRARI, MATHEUS R.; TREVISAN-SILVA, DILZA; MEISSNER, GABRIEL O.; VUITIKA, LARISSA; MARIN, BRENDA; TASHIMA, ALEXANDRE K.; GREMSKI, LUIZA H.; GREMSKI, WALDEMIRO; SENFF-RIBEIRO, ANDREA; et al. Expression and immunological cross-reactivity of LALP3, a novel astacin-like metalloprotease from brown spider (Loxosceles intermedia) venom. Biochimie, v. 128, p. 8-19, SEP-OCT 2016. Web of Science Citations: 3. (12/19321-9)
DASGUPTA, SAYANI; YANG, CIYU; CASTRO, LEANDRO M.; TASHIMA, ALEXANDRE K.; FERRO, EMER S.; MOIR, ROBYN D.; WILLIS, IAN M.; FRICKER, LLOYD D.. Analysis of the Yeast Peptidome and Comparison with the Human Peptidome. PLoS One, v. 11, n. 9, SEP 29 2016. Web of Science Citations: 6. (12/19321-9)
COA, LARISSA LEGGIERI; ABREU, THIAGO FERREIRA; TASHIMA, ALEXANDRE KEIJI; GREEN, JANAINA; PASCON, RENATA CASTIGLIONI; VALLIM, MARCELO AFONSO; MACHADO-, JR., JOEL. AKT/protein kinase B associates with beta-actin in the nucleus of melanoma cells. BIOSCIENCE REPORTS, v. 39, n. 1, JAN 31 2019. Web of Science Citations: 1. (12/19321-9)
PEDROSO, AMANDA P.; DORNELLAS, ANA P. S.; DE SOUZA, ADRIANA P.; PAGOTTO, JOSIAS F.; OYAMA, LILA M.; NASCIMENTO, CLAUDIA M. O.; KLAWITTER, JELENA; CHRISTIANS, UWE; TASHIMA, ALEXANDRE K.; RIBEIRO, ELIANE BERALDI. A proteomics-metabolomics approach indicates changes in hypothalamic glutamate-GABA metabolism of adult female rats submitted to intrauterine growth restriction. EUROPEAN JOURNAL OF NUTRITION, v. 58, n. 8, p. 3059-3068, DEC 2019. Web of Science Citations: 1. (12/19321-9, 10/20268-0)
TASHIMA, ALEXANDRE KEIJI; CASTILHO, DANIELE GONCALVES; ALENCAR CHAVES, ALISON FELIPE; XANDER, PATRICIA; ZELANIS, ANDRE; BATISTA, WAGNER LUIZ. Data in support of quantitative proteomics to identify potential virulence regulators in Paracoccidioides brasiliensis isolates. DATA IN BRIEF, v. 5, p. 155-160, DEC 2015. Web of Science Citations: 0. (14/13961-1, 12/19321-9, 11/14392-2)
DE MELO, AMANDA TEIXEIRA; MARTHO, KEVIN FELIPE; ROBERTO, THIAGO NUNES; NISHIDUKA, ERIKA S.; MACHADO JR, JOEL; BRUSTOLINI, OTAVIO J. B.; TASHIMA, ALEXANDRE K.; TEREZAVASCONCELOS, ANA; VALLIM, MARCELO A.; PASCON, RENATA C.. The regulation of the sulfur amino acid biosynthetic pathway in Cryptococcus neoformans: the relationship of Cys3, Calcineurin, and Gpp2 phosphatases. SCIENTIFIC REPORTS, v. 9, AUG 15 2019. Web of Science Citations: 2. (18/20390-1, 15/04400-9, 17/20106-9, 16/14542-8)
BITTENCOURT RODRIGUES, CAROLINE FABRI; SERINO-SILVA, CAROLINE; DE MORAIS-ZANI, KAREN; KAVAZOI, VICTOR KOITI; NOGUEIRA CARVALHO, MARCELO PIRES; GREGO, KATHLEEN FERNANDES; CHIARELLI, TASSIA; TASHIMA, ALEXANDRE KEIJI; TOYAMA, MARCOS HIKARI; TANAKA-AZEVEDO, ANITA MITICO. Boa.PLI: Structural and functional characterization of the gamma phospholipase A2 plasma inhibitor from the non-venomous Brazilian snake Boa constrictor. PLoS One, v. 15, n. 2, FEB 27 2020. Web of Science Citations: 0. (17/20106-9, 17/16908-2, 18/25786-0)
VENANCIO DE LIMA, EDUARDO OLIVEIRA; TASIMA, LIDIA JORGE; HATAKEYAMA, DANIELA MIKI; SERINO-SILVA, CAROLINE; BITTENCOURT RODRIGUES, CAROLINE FABRI; GALIZIO, NATHALIA DA COSTA; CHIARELLI, TASSIA; NISHIDUKA, ERIKA SAYURI; TEIXEIRA DA ROCHA, MARISA MARIA; SANT'ANNA, SAVIO STEFANINI; et al. Snake venom color and L-amino acid oxidase: An evidence of long-term captive Crotalus durissus terrificus venom plasticity. Toxicon, v. 193, p. 73-83, APR 15 2021. Web of Science Citations: 0. (17/16908-2, 17/21052-0, 14/11108-0, 18/25786-0, 18/14724-4, 16/09976-9, 17/01890-0, 17/20106-9)
PINO, JESSICA M. V.; NISHIDUKA, ERIKA S.; DA LUZ, MARCIO H. M.; SILVA, VITORIA F.; ANTUNES, HANNA K. M.; TASHIMA, ALEXANDRE K.; GUEDES, PEDRO L. R.; DE SOUZA, ALTAY A. L.; LEE, KIL S.. Iron-deficient diet induces distinct protein profile related to energy metabolism in the striatum and hippocampus of adult rats. NUTRITIONAL NEUROSCIENCE, MAR 2020. Web of Science Citations: 0. (17/20106-9, 16/04297-6)
HATAKEYAMA, DANIELA MIKI; TASIMA, LIDIA JORGE; GALIZIO, NATHALIA DA COSTA; SERINO-SILVA, CAROLINE; FABRI BITTENCOURT RODRIGUES, CAROLINE; STUGINSKI, DANIEL RODRIGUES; SANT'ANNA, SAVIO STEFANINI; GREGO, KATHLEEN FERNANDES; TASHIMA, ALEXANDRE KEIJI; NISHIDUKA, ERIKA SAYURI; et al. From birth to adulthood: An analysis of the Brazilian lancehead (Bothrops moojeni) venom at different life stages. PLoS One, v. 16, n. 6, JUN 10 2021. Web of Science Citations: 0. (17/16908-2, 17/20106-9, 18/25786-0, 18/25899-0, 18/14724-4)
DE MORAIS-ZANI, KAREN; SERINO-SILVA, CAROLINE; GALIZIO, NATHALIA DA COSTA; TASIMA, LIDIA JORGE; PAGOTTO, JOSIAS FALARARO; TEIXEIRA DA ROCHA, MARISA MARIA; MARCELINO, JOSE ROBERTO; SANT'ANNA, SAVIO STEFANINI; TASHIMA, ALEXANDRE KEIJI; TANAKA-AZEVEDO, ANITA MITICO; et al. Does the administration of pilocarpine prior to venom milking influence the composition of Micrurus corallinus venom?. JOURNAL OF PROTEOMICS, v. 174, p. 17-27, MAR 1 2018. Web of Science Citations: 3. (16/09976-9, 12/19321-9, 14/11108-0, 17/01890-0)
(References retrieved automatically from State of São Paulo Research Institutions)
TASHIMA, Alexandre Keiji. Estudo da precipitação isoeletrica da insulina suina em soluções aquosas com o dioxido de carbono. Tese (Doutorado) - Faculdade de Engenharia Química. Universidade Estadual de Campinas (UNICAMP). (02/13836-5)