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Houtan Noushmehr

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Universidade de São Paulo (USP). Faculdade de Medicina de Ribeirão Preto (FMRP)  (Institutional affiliation for the last research proposal)
Birthplace: Inglaterra

Graduated in Physiological Sciences and History from the University of California, Los Angeles (UCLA) (1999); master's degree in Biology from California State University (CSULA), Los Angeles (2003), Masters in Bioinformatics Johns Hopkins University (JHU) (2006) and Ph.D. in Genetics from the University of Southern California (USC) (2011). He did post-doctoral fellow in genetics at the University of Southern California. Has experience in the areas of General Biology, with emphasis on molecular biology, epigenetics, DNA methylation, Cancer, study of the genome. He participated in the analysis of data from the consortium "Human Genomics Cancer Research." And experienced in designing and / or development of algorithms in Bioinformatics / Molecular Biology for analyzing massive amounts of data (high data throughput), focusing on the study focus on genomics, genetics, epigenetics, epigenome human .. Experience in online teaching and the creation and organization of courses. English: Bioinformatician/Molecular Biologist specialist - design and/or implement innovative algorithms and statistical packages for high throughput data analysis, focus on human genomics/genetics/epigenomics/epigenetics. See publication list at PubMed ( Instruction - designed and administrated molecular biology courses/workshops with laboratory; attended and participated at international scientific meeting such as Diabetes (USA), Endocrinology (Brazil), Society of Developmental Biology (USA), American Association for Cancer Research, The Cancer Genome Atlas (TCGA) conferences. Specialties Bioinformatics: R statistical packages, Bioconductor, Perl, Bioperl, SQL, and functional in other computer programing applications to assist in biological discovery. Molecular Biology: Genetic engineering such as cloning, genetic mutation; DNA/RNA/Protein extractions and visualization techniques such as RT-PCR, qPCR, northern, southern, western; siRNA/shRNA constructs; retrovirus/lentivirus production for efficient delivery of gene of interest; Human cell culture. (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated October 19, 2019
Total / Available in English
Most frequent collaborators in research granted by FAPESP
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Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.





Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (15)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Data from Web of Science

SILVA, TIAGO C.; COETZEE, SIMON G.; GULL, NICOLE; YAO, LIJING; HAZELETT, DENNIS J.; NOUSHMEHR, HOUTAN; LIN, DE-CHEN; BERMAN, BENJAMIN R.. ELMER v.2: an R/Bioconductor package to reconstruct gene regulatory networks from DNA methylation and transcriptome profiles. Bioinformatics, v. 35, n. 11, p. 1974-1977, . Web of Science Citations: 2. (15/07925-5, 16/01389-7)


PRENDERGAST, EMILY N.; DE SOUZA FONSECA, MARCOS ABRAAO; DEZEM, FELIPE SEGATO; LESTER, JENNY; KARLAN, BETH Y.; NOUSHMEHR, HOUTAN; LIN, XIANZHI; LAWRENSON, KATE. Optimizing exosomal RNA isolation for RNA-Seq analyses of archival sera specimens. PLoS One, v. 13, n. 5, . Web of Science Citations: 3.

MAZOR, TALI; CHESNELONG, CHARLES; PANKOV, ALEKSANDR; JALBERT, LLEWELLYN E.; HONG, CHIBO; HAYES, JOSIE; SMIRNOV, IVAN V.; MARSHALL, ROXANNE; SOUZA, CAMILA F.; SHEN, YAOQING; et al. Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v. 114, n. 40, p. 10743-10748, . Web of Science Citations: 27. (15/07925-5, 14/08321-3, 16/15485-8)

COLAPRICO, ANTONIO; SILVA, TIAGO C.; OLSEN, CATHARINA; GAROFANO, LUCIANO; CAVA, CLAUDIA; GAROLINI, DAVIDE; SABEDOT, THAIS S.; MALTA, TATHIANE M.; PAGNOTTA, STEFANO M.; CASTIGLIONI, ISABELLA; et al. TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data. Nucleic Acids Research, v. 44, n. 8, . Web of Science Citations: 173. (15/07925-5, 15/02844-7, 14/02245-3)

CECCARELLI, MICHELE; BARTHEL, FLORIS P.; MALTA, TATHIANE M.; SABEDOT, THAIS S.; SALAMA, SOFIE R.; MURRAY, BRADLEY A.; MOROZOVA, OLENA; NEWTON, YULIA; RADENBAUGH, AMIE; PAGNOTTA, STEFANO M.; et al. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell, v. 164, n. 3, p. 550-563, . Web of Science Citations: 494. (15/07925-5, 15/02844-7, 14/08321-3, 14/02245-3)

MELISO, FABIANA M.; MICALI, DANILO; SILVA, CAMILA T.; SABEDOT, THAIS S.; COETZEE, SIMON G.; KOCH, ADRIAN; FAHLBUSCH, FABIAN B.; NOUSHMEHR, HOUTAN; SCHNEIDER-STOCK, REGINE; JASIULIONIS, MIRIAM G.. SIRT1 regulates Mxd1 during malignant melanoma progression. ONCOTARGET, v. 8, n. 70, p. 114540-114553, . Web of Science Citations: 4. (15/07925-5, 11/12306-1, 14/13663-0, 16/06488-3)

ALDAPE, KENNETH; AMIN, SAMIRKUMAR B.; ASHLEY, DAVID M.; BARNHOLTZ-SLOAN, JILL S.; BATES, AMANDA J.; BEROUKHIM, RAMEEN; BOCK, CHRISTOPH; BRAT, DANIEL J.; CLAUS, ELIZABETH B.; COSTELLO, JOSEPH F.; et al. Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium. NEURO-ONCOLOGY, v. 20, n. 7, p. 873-884, . Web of Science Citations: 9. (15/07925-5, 14/08321-3, 16/15485-8)

MALTA, TATHIANE M.; SOKOLOV, ARTEM; GENTLES, ANDREW J.; BURZYKOWSKI, TOMASZ; POISSON, LAILA; WEINSTEIN, JOHN N.; KAMINSKA, BOZENA; HUELSKEN, JOERG; OMBERG, LARSSON; GEVAERT, OLIVIER; et al. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell, v. 173, n. 2, p. 338+, . Web of Science Citations: 68. (16/06488-3, 16/12329-5, 15/07925-5, 14/08321-3, 16/15485-8, 16/01389-7, 16/10436-9, 16/01975-3, 14/02245-3)

MALTA, TATHIANE M.; DE SOUZA, CAMILA F.; SABEDOT, THAIS S.; SILVA, TIAGO C.; MOSELLA, MARITZA S.; KALKANIS, STEVEN N.; SNYDER, JAMES; CASTRO, ANA VALERIA B.; NOUSHMEHR, HOUTAN. Glioma CpG island methylator phenotype (G-CIMP): biological and clinical implications. NEURO-ONCOLOGY, v. 20, n. 5, p. 608-620, . Web of Science Citations: 16. (16/11039-3, 16/06488-3, 16/12329-5, 15/07925-5, 14/08321-3, 16/15485-8, 16/01389-7, 16/10436-9, 16/01975-3, 14/02245-3)

DE SOUZA, CAMILA FERREIRA; SABEDOT, THAIS S.; MALTA, TATHIANE M.; STETSON, LINDSAY; MOROZOVA, OLENA; SOKOLOV, ARTEM; LAIRD, PETER W.; WIZNEROWICZ, MACIEJ; IAVARONE, ANTONIO; SNYDER, JAMES; et al. A Distinct DNA Methylation Shift in a Subset of Glioma CpG Island Methylator Phenotypes during Tumor Recurrence. CELL REPORTS, v. 23, n. 2, p. 637-651, . Web of Science Citations: 16. (14/03989-6, 16/06488-3, 16/12329-5, 15/07925-5, 14/08321-3, 16/15485-8, 16/01975-3, 14/02245-3)

GARCIA-ROSA, SHEILA; TRIVELLA, DANIELA B. B.; MARQUES, VANESSA D.; SERAFIM, RODOLFO B.; PEREIRA, JOSE G. C.; LORENZI, JULIO C. C.; MOLFETTA, GREICE A.; CHRISTO, PAULO P.; OLIVAL, GUILHERME S.; MARCHITTO, VANIA B. T.; et al. A non-functional galanin receptor-2 in a multiple sclerosis patient. PHARMACOGENOMICS JOURNAL, v. 19, n. 1, p. 72-82, . Web of Science Citations: 1. (15/07925-5, 13/24293-7, 16/06488-3)

GUSEV, ALEXANDER; LAWRENSON, KATE; LIN, XIANZHI; LYRA, JR., PAULO C.; KAR, SIDDHARTHA; VAVRA, KEVIN C.; SEGATO, FELIPE; FONSECA, MARCOS A. S.; LEE, JANET M.; PEJOVIC, TANYA; et al. A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variants. Nature Genetics, v. 51, n. 5, p. 815+, . Web of Science Citations: 1. (15/07925-5)

LAWRENSON, KATE; SONG, FENGJU; HAZELETT, DENNIS J.; KAR, SIDDHARTHA P.; TYRER, JONATHAN; PHELAN, CATHERINE M.; CORONA, ROSARIO I.; RODRIGUEZ-MALAVE, NORMA I.; SEO, JI-HEI; ADLER, EMILY; et al. Genome-wide association studies identify susceptibility loci for epithelial ovarian cancer in east Asian women. GYNECOLOGIC ONCOLOGY, v. 153, n. 2, p. 343-355, . Web of Science Citations: 0. (15/07925-5)

MOUNIR, MOHAMED; LUCCHETTA, MARTA; SILVA, TIAGO C.; OLSEN, CATHARINA; BONTEMPI, GIANLUCA; CHEN, XI; NOUSHMEHR, HOUTAN; COLAPRICO, ANTONIO; PAPALEO, ELENA. New functionalities in the TCGAbiolinks package for the study and integration of cancer data from GDC and GTEx. PLOS COMPUTATIONAL BIOLOGY, v. 15, n. 3, . Web of Science Citations: 2. (15/07925-5, 16/01389-7)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SILVA, Tiago Chedraoui. Ferramenta de bioinformática para integrar e compreender as mudanças epigenômicas e genômicas aberrantes associadas com câncer: métodos, desenvolvimento e análise. 2018. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (16/01389-7)

SABEDOT, Thaís Sarraf. Classificação molecular de gliomas difusos em adulto baseada em metilação do DNA revela subgrupos de tumores G-CIMP associados com aspectos clínicos distintos. 2018. Tese (Doutorado) – Faculdade de Medicina de Ribeirão Preto. Universidade de São Paulo (USP). Ribeirão Preto. (16/06488-3)

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