Abstract
Several pieces of evidence indicate that glutamate- and nitric oxide-mediated neurotransmission facilitate defensive responses coordinated by the dorsolateral periaqueductal gray (dlPAG). In addition, other neurotransmitters present in the dlPAG could also modulate these responses, including the endovanilloids. Activation of vanilloid TRPV1 receptors facilitates glutamatergic neurotransm…