CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Fisioterapia from Pontifícia Universidade Católica de Campinas (1980), master's at Immunology from Universidade Estadual de Campinas (1991) and ph.d. at Genetics from Universidade Estadual de Campinas (1996). Has experience in Immunology, focusing on Celular Imunology, acting on the following subjects: paracoccidioides brasiliensis, trypanosoma cruzi, paracocidioides brasiliensis, gliomas and mhv. (Source: Lattes Curriculum)
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Dendritic cells (DCs) are able to polarize the immune response towards an inflammatory or anti-inflammatory context depending on its maturation/activation status, leading to the generation of regulatory T cells or Th1, Th2, Th9 and Th17 profiles. Immature DCs are also called tolerogenic DCs. An increasing number of studies have demonstrated that DC modulation is an innovative approach to …
The thymus is the lymphoid organ responsible for generating T lymphocytes and thus preserving its microenvironment is critical to the development and maintenance of robust immune responses. However, despite its importance, a number of factors, such as stress, poor nutrition, drugs used in treatment against cancers and infectious diseases, are able to promote changes in the thymic microenv…
FUNDAMENTO: A modulação de processos inflamatórios, na maior parte orquestrado por células T reguladoras (Treg) e células dendríticas supressivas (DCs), é um passo necessário para evitar o desenvolvimento de respostas deletérias e doenças auto-imunes. Terapias que visam a transferência adotiva de células Treg, ou sua expansão in vivo, alcançaram grande sucesso no controle da inflamação em…
(Only some records are available in English at this moment)
The Experimental Autoimmune Encephalomyelitis (EAE), a murine model for the study of multiple sclerosis, consists in a chronical inflammation of the neural tissue triggered by the immune response against components of the central nervous system, resulting in the gradual loss of the neuromotor functions. The autoimmune neuro-inflammation is orchestrated by cells and molecules that infiltra…
Dendritic cells (DCs), antigen-presenting cells, are able to polarize the immune response towards an inflammatory or anti-inflammatory context depending on its maturation/activation status, leading to the generation of regulatory T cells or Th1, Th2, Th9 and Th17 profiles. Immature DCs are also called tolerogenic DCs. The modulation of DCs may be an innovative approach to control chronic …
Dendritic cells (DCs) are capable to direct the immune response towards an inflammatory or anti-inflammatory context, depending on its maturation/activation status. Immature DCs have the ability to generate regulatory T cells while mature/activated DCs express high levels of the major histocompatibility complex molecules together with co-stimulatory signals that drive T cells towards an i…
(Only some records are available in English at this moment)
Thymus is the primary lymphoid organ responsible for T lymphocytes development. Thymocyte intrathymic migration is essential for its maturation, process through which they receive the necessary signal for their survival, proliferation and differentiation. These signals are derived from thymic stromal components comprising the thymic epithelial cells, fibroblasts, extracellular matrix comp…
| 17 / 9 | Completed research grants |
| 25 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 43 / 20 | All research grants and scholarships |
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