CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
PhD in Biology of Host-Pathogen Relationship from University of São Paulo (2001) and formerly a post-doctoral fellow at the Dept. of Microbiology and Immunology at Virginia Commonwealth University. Research focusing on structural, functional, and evolutionary aspects of bacteria and parasitic protozoa. Main interests include bioinformatics and molecular biology, in particular evolution and genomics. Working mainly on: phylogeny, assembly, analysis and annotation of genomes and transcriptomes (using "next generation" high-throughput methodologies), gene expression analysis (RNA-Seq), use of relational databases for management and presentation of biological data, and computer programming for the analysis of biological data. (Source: Lattes Curriculum)
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Recent sequencing and analysis of eukaryotic genomes and transcriptomes has led to the discovery of several biological phenomena, in addition to answering old pending questions on the evolution, phylogeny, and cellular and molecular biology of these organisms. However, sampling of organisms analyzed so far has been very biased and uneven, given the emphasis given in previous research to o…
Among eukaryotes, the cell surface protein composition is highly specialized to support different lifestyles, participating in immune evasion, cell invasion, migration and environmental interaction. This notorious mutability and variation can be explored through comparative analyzes in a monophyletic group that presents great diversity, correlating these proteins with different lifestyles…
Endotrypanum spp. is a hemoflagellate protozoan parasite (Order Kinetoplastida, Family Trypanosomatidae) presenting a dixenous life cycle, alternating between insect vectors such as phlebotomines and the mammalian hosts. Endotrypanum is the only trypanosomatid that infects mammalian erythrocytes, such as those from sloths from the genera Choloepus and Bradypus. Endotrypanum schaudinni pre…
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