CV Lattes
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Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Prof. Dr. Luiz Alberto Berlado de Moraes was graduated in Chemistry from the State University of Londrina (1991), master's degree in Chemistry from the State University of Campinas (1995) and a PhD in Chemistry from the State University of Campinas (2000). He is currently associate professor in the chemistry department FFCLRP of the University of São Paulo. He is group leader of the Mass Spectrometry applied to bioactive Natural Products. Has experience in Organic Chemistry with emphasis on liquid chromatography coupled mass spectrometry (LC-MS / MS), acting on the following topics: dereplication of crude microbial extracts, isolation of bioactive secondary metabolites produced by actinomycetes and development analytical methods using tandem mass spectrometry. (Source: Lattes Curriculum)
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The main objective of this project is to develop new technologies for the removal of taste and odor, particularly two semi-volatile compounds 2-methylisoborneol (MIB), geosmin and Nitrosamines where the goal is to replace activated carbon technology and current membranes. Two classes of filter elements and / or adsorbents will be developed and studied. The first involves a class of low-co…
The importance of microbial natural product chemistry as a source of bioactive molecules is undoubted. The isolation and identification of secondary metabolites produced by microorganisms is very important for the chemical, pharmaceutical and agrochemical industries. Studies have revealed that some microbial secondary metabolites, encoded in the genomes, remain to be discovered, probably …
Actinomycetes produce a variety of natural products that are of major importance in the agrochemical and pharmaceutical industry. More than 50% of all anti-infective and anticancer compounds developed over the past 25 years have been natural products or derivatives thereof. Recent advances in genome sequencing have revealed that such organisms have the potential to yield even more structu…
Microorganisms, in particular the actinomycetes are known to produce a vast number of bioactive secondary metabolites of interesting pharmaceuticals and agrochemical industry. Rapid detection of bioactive compounds plays strategic' role in their natural products investigation. TLC is one of the most frequently used chromatographic methods for separating complex chemical compounds. Several…
(Only some records are available in English at this moment)
Microorganisms are an inexhaustible and important source of bioactive secondary metabolites with different modes of action. Actinobacteria have been shown to be efficient in carrying out the biosynthesis of a wide variety of bioactive secondary metabolites, especially antibiotics. Various strategies have been applied for the activation of microbial cryptic pathways, such as OSMAC, heterol…
The main objective of this project is to develop new technologies for the removal of taste and odor, particularly two semi-volatile compounds 2-methylisoborneol (MIB), geosmin and Nitrosamines where the goal is to replace activated carbon technology and current membranes. Two classes of filter elements and/or adsorbents will be developed and studied. The first involves a class of low cost…
Microorganisms are an inexhaustible and important source of bioactive secondary metabolites with different modes of action. Actinobacteria have been shown to be efficient for carrying out the biosynthesis of a wide variety of bioactive secondary metabolites, in particular antibiotics. Several strategies have been applied for the activation of cryptic microbial pathways, such as OSMAC, het…
(Only some records are available in English at this moment)
The metabolites 2-methylisoborneol and geosmin, responsible for earthy taste and odor of tap water, and the possible carcinogenic N-nitrosamines are emerging contaminants that can be present in drinking water and present harmful effects in the concentration range of nanogram per liter. Water treatment in Drinking Water Treatment Plants is not always effective in removing these contaminant…
Actinobacteria, especially of the genus Streptomyces, are an inexhaustible source of bioactive secondary metabolites, particularly for the discovery of new active ingredients of industrial interest. Although actinobacteria have the ability to biosynthesize a wide variety of molecules, recent advances in genome sequencing have shown that these microorganisms have an even greater potential…
| 1 / 1 | Ongoing grants |
| 8 / 6 | Completed research grants |
| 15 / 9 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 26 / 18 | All research grants and scholarships |
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