Abstract
The carbon monoxide (CO) is a neuromodulator gas which may be involved in apoptosis, cellular proliferation, inflammation and the emotional behavior, for instance, the anxiety modulation. The CO can act on the anxiety in a process dependent of kinase protein C which is activated by soluble guanylate cyclase and 3'-5'-guanosine monophosphate. This mechanism can modulate noradrenergic neuro…