graduate at Odontologia from Universidade Estadual Paulista Júlio de Mesquita Filho (1995), master's at Anatomy from Universidade de São Paulo (2002) and ph.d. at Anatomy from Universidade de São Paulo (2007). Has experience in Morphology, focusing on Anatomy, acting on the following subjects: serotonin, suprachiasmatic nucleus and raphe nuclei. (Source: Lattes Curriculum)
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The clock genes Period (per) 1 and 2 are essential components in the generation and adjustment of biological circadian rhythms by the suprachiasmatic nucleus (SCN). Both genes are also rhythmically present in extra-hypothalamic areas such as the hippocampus and cerebellum, considered subordinate oscillators. Several pathological conditions alter rhythmic biological phenomena, but the mech…
Extra-pineal production of melatonin induced by injury is being described in peripheral immune competent cells. Molecules that signalize injury, such as pro-inflammatory cytokines and PAMPs suppress pineal melatonin production and induce the synthesis of this indolamine by mononuclear and polymorphonuclear cells. The pivotal transcription factor in inflammatory responses, nuclear factor k…
Sleep is essential for infant's cognitive, motor and comportamental development. The hypothalamus' suprachiasmatic nucleus is responsible for the generation of several circadian rhythms including the synthesis of the hormone melatonin, variations in temperature and sleep-wake transition that undergo external interferences such as dark-light cycle. Melatonin, wich is synthesized and releas…
Obesity, characterized by accumulation of body fat, affects a third of the world population. Among the many complications of obesity are sleep disorders including obstructive sleep apnea (OSA ) and snoring. The latter, caused mostly by central fat accumulation, may be a sign and also lead to worsening of the OSA clinical state. Among the treatment options for snoring and OSA are speech la…
The endotoxin lipopolysaccharide (LPS), when administered to a pregnant female during the gestation period, increase proinflammatory cytokines, mimicking prenatal inflammation frame. Thus, the offspring of rats exposed to LPS presents problems in neurodevelopment which result in behavioral and cognitive problems. Among the various pathologies involving disturbances in neurodevelopment is …
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| 3 / 2 | Completed research grants |
| 14 / 8 | Completed scholarships in Brazil |
| 17 / 10 | All research grants and scholarships |
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CV Lattes
ORCID