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Márcio Luís Andrade e Silva

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Universidade de Franca (UNIFRAN). Reitoria  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

graduation at Farmácia Industrial from Faculdade de Ciências Farmaceûticas de Ribeirão Preto Usp (1989), master's at Fármacos e Medicamentos from Faculdade de Ciências Farmaceûticas de Ribeirão Preto Usp (1992) and doctorate at Ciências from Faculdade de Filosofia Ciências E Letras de Ribeirão Preto Usp (1999). Has experience in Chemistry, focusing on Chemistry of the Natural Products, acting on the following subjects: lignanas, piper cubeba, (-)-cubebina, atividade antimicrobiana and atividade analgésica. (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (19)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications14
Citations123
Cit./Article8.8
Data from Web of Science

ESPERANDIM, VIVIANE RODRIGUES; FERREIRA, DANIELE DA SILVA; SOUSA REZENDE, KAREN CRISTINA; MAGALHAES, LIZANDRA GUIDI; SOUZA, JULIA MEDEIROS; PAULETTI, PATRICIA MENDONCA; JANUARIO, ANA HELENA; DE LAURENTZ, ROSANGELA DA SILVA; BASTOS, JAIRO KENUPP; SIMARO, GUILHERME VENANCIO; et al. In Vitro Antiparasitic Activity and Chemical Composition of the Essential Oil Obtained from the Fruits of Piper cubeba. Planta Medica, v. 79, n. 17, p. 1653-1655, . Web of Science Citations: 20.

TIMPLE, JULIE MARIE V.; MAGALHAES, LIZANDRA GUIDI; SOUZA REZENDE, KAREN CRISTINA; PEREIRA, ANA CAROLINA; CUNHA, WILSON ROBERTO; ANDRADE E SILVA, MARCIO LUIS; MORTENSEN, OLE VALENTE; FONTANA, ANDREIA C. K.. The Lignan (-)-Hinokinin Displays Modulatory Effects on Human Monoamine and GABA Transporter Activities. Journal of Natural Products, v. 76, n. 10, p. 1889-1895, . Web of Science Citations: 11. (08/02717-1, 09/15207-4)

DE OLIVEIRA, POLLYANNA FRANCIELLI; ACESIO, NATHALIA OLIVEIRA; LEANDRO, LUIS FERNANDO; CUNHA, NAYANNE LARISSA; DE MENDONCA UCHOA, CAMILA JACINTHO; JANUARIO, ANA HELENA; TAVARES, DENISE CRISPIM. Antigenotoxicity of Roupala montana extract in the mouse micronucleus and comet assays. DRUG AND CHEMICAL TOXICOLOGY, v. 37, n. 1, p. 93-99, . Web of Science Citations: 1.

LIMA, THAIS C.; LUCARINI, RODRIGO; VOLPE, ANGELICA C.; DE ANDRADE, CAROLINA Q. J.; SOUZA, ALICE M. P.; PAULETTI, PATRICIA M.; JANUARIO, ANA H.; SIMARO, GUILHERME V.; BASTOS, JAIRO K.; CUNHA, WILSON R.; et al. In vivo and in silico anti-inflammatory mechanism of action of the semisynthetic (-)-cubebin derivatives (-)-hinokinin and (-)-O-benzylcubebin. Bioorganic & Medicinal Chemistry Letters, v. 27, n. 2, p. 176-179, . Web of Science Citations: 6. (11/07623-8)

LUZ‚ P.P.; MAGALHÃES‚ L.G.; PEREIRA‚ A.C.; CUNHA‚ W.R.; RODRIGUES‚ V.; ANDRADE E SILVA‚ M.L.. Curcumin-loaded into PLGA nanoparticles. Parasitology Research, p. 1-6, . (09/05049-2, 09/15207-4)

PEREIRA, A. C.; MAGALHAES, L. G.; GONCALVES, U. O.; LUZ, P. P.; MORAES, A. C. G.; RODRIGUES, V.; DA MATTA GUEDES, P. M.; DA SILVA FILHO, A. A.; CUNHA, W. R.; BASTOS, J. K.; et al. Schistosomicidal and trypanocidal structure-activity relationships for (+/-)-licarin A and its (-)- and (+)-enantiomers. Phytochemistry, v. 72, n. 11-12, p. 1424-1430, . Web of Science Citations: 26. (09/15207-4, 09/05049-2)

NERES, NAYARA B. R.; MONTAGNINI, DANIEL; FERREIRA, DANIELE S.; PARREIRA, RENATO L. T.; ORENHA, RENATO P.; LIMA, THAIS C.; MOLINA, EDUARDO F.; CUNHA, WILSON R.; SILVA, MARCIO L. A.; ESPERANDIM, VIVIANE R.. In Vivo and in Silico Trypanocidal Activity Evaluation of (-)-Cubebin Encapsulated in PLGA Microspheres as Potential Treatment in Acute Phase. CHEMISTRY & BIODIVERSITY, v. 18, n. 6, . Web of Science Citations: 0. (09/05049-2, 13/04880-5, 17/24856-2, 11/07623-8, 11/05952-4, 10/17378-8)

LIZANDRA G. MAGALHÃES; THAIS C. LIMA; RENATO G. DE PAULA; ENYARA R. MORAIS; DANIELA P. AGUIAR; LUIZ G. GARDINASSI; GUSTAVO R. GARCIA; ROSANGELA S. LAURENTIZ; VANDERLEI RODRIGUES; JAIRO K. BASTOS; et al. Effects of (-)-6,6'-dinitrohinokinin on adult worms of Schistosoma mansoni: a proteomic analyses. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 26, n. 3, p. -, . (13/00382-0, 09/15207-4, 10/17378-8)

DOS SANTOS FILHO, LEODORO P.; NASCIMENTO, DE F. P. MARIA P.; MARCAL, LIZIANE; CIUFFI, KATIA J.; SILVA, MARCIO L. A. E; NASSAR, EDUARDO J.; ROCHA, LUCAS A.. (-)-Hinokinin antimicrobial agents into functionalized mesoporous silica. Journal of Sol-Gel Science and Technology, v. 98, n. 2, . Web of Science Citations: 0. (19/02641-0, 15/20298-0)

LUZ, PRISCILLA P.; MAGALHAES, LIZANDRA G.; PEREIRA, ANA CAROLINA; CUNHA, WILSON R.; RODRIGUES, VANDERLEI; ANDRADE E SILVA, MARCIO L.. Curcumin-loaded into PLGA nanoparticles. Parasitology Research, v. 110, n. 2, p. 593-598, . Web of Science Citations: 25. (09/15207-4, 09/05049-2)

MAGALHAES, LIZANDRA G.; LIMA, THAIS C.; DE PAULA, RENATO G.; MORAIS, ENYARA R.; AGUIAR, DANIELA P.; GARDINASSI, LUIZ G.; GARCIA, GUSTAVO R.; LAURENTIZ, ROSANGELA S.; RODRIGUES, VANDERLEI; BASTOS, JAIRO K.; et al. Effects of (-)-6,6 `-dinitrohinokinin on adult worms of Schistosoma mansoni: a proteomic analyses. REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY, v. 26, n. 3, p. 334-341, . Web of Science Citations: 0. (10/17378-8, 09/15207-4, 13/00382-0)

ANDRADE E SILVA, MARCIO LUIS; ESPERANDIM, VIVIANE RODRIGUES; FERREIRA, DANIELE DA SILVA; MAGALHAES, LIZANDRA GUIDI; LIMA, THAIS COELHO; CUNHA, WILSON ROBERTO; NANAYAKKARA, DHAMMIKA N. P.; PEREIRA, ANA CAROLINA; BASTOS, JAIRO KENUPP. Furofuran lignans display schistosomicidal and trypanocidal activities. Phytochemistry, v. 107, p. 119-125, . Web of Science Citations: 2. (09/15207-4, 09/05049-2, 11/10179-2)

PEREIRA, ANA C.; SILVA, MARCIO L. A. E; SOUZA, JULIA MEDEIROS; DE LAURENTIZ, ROSANGELA S.; RODRIGUES, VANDERLEI; JANUARIO, ANA H.; PAULETTI, PATRICIA M.; TAVARES, DENISE C.; DA SILVA FILHO, ADEMAR A.; CUNHA, WILSON R.; et al. In vitro and in vivo anthelmintic activity of (-)-6,6 `-dinitrohinokinin against schistosomula and juvenile and adult worms of Schistosoma mansoni. Acta Tropica, v. 149, p. 195-201, . Web of Science Citations: 12. (10/17378-8, 09/15207-4, 11/10179-2)

MELETI, VANDERLISA RITA; ESPERANDIM, VIVIANE RODRIGUES; BOCALON FLAUZINO, LUZIO GABRIEL; PRIZANTELLI, ANNA HELENA; DE LIMA PAULA, LUCAS ANTONIO; MAGALHAES, LIZANDRA GUIDI; CUNHA, WILSON ROBERTO; LAURENTIZ, ROSANGELA DA SILVA; DA ROCHA PISSURNO, ANA PAULA; DHAMMIKA NANAYAKKARA, N. P.; et al. (+/-)-Licarin A and its semi-synthetic derivatives: In vitro and in silico evaluation of trypanocidal and schistosomicidal activities. Acta Tropica, v. 202, . Web of Science Citations: 0. (11/07623-8, 09/05049-2, 17/24856-2)

PEREIRA, ANA CAROLINA; MAGALHAES, LIZANDRA G.; JANUARIO, ANA HELENA; PAULETTI, PATRICIA M.; CUNHA, WILSON ROBERTO; BASTOS, JAIRO KENUPP; NANAYAKKARA, DHAMMIKA N. P.; E SILVA, MARCIO LUIS A.. Enantiomeric resolution of (+/-)-licarin A by high-performance liquid-chromatography using a chiral stationary phase. Journal of Chromatography A, v. 1218, n. 39, p. 7051-7054, . Web of Science Citations: 5. (09/15207-4, 09/05049-2)

SILVA, MARCIO LUIS A.; MARTINS, CARLOS H. G.; LUCARINI, RODRIGO; SATO, DAISY N.; PAVAN, FERNANDO R.; FREITAS, NAYARA H. A.; ANDRADE, LEONARDO N.; PEREIRA, ANA C.; BIANCO, THAIS N. C.; VINHOLIS, ADRIANA H. C.; et al. Antimycobacterial Activity of Natural and Semi-Synthetic Lignans. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES, v. 64, n. 11-12, p. 779-784, . Web of Science Citations: 15.

SILVA‚ MLA; COÍMBRA‚ HS; PEREIRA‚ AC; ALMEIDA‚ VA; LIMA‚ TC; COSTA‚ ES; VINHOLIS‚ AHC; ROYO‚ VA; SILVA‚ R.; CUNHA‚ WR; et al. Evaluation of piper cubeba extract‚(-)-cubebin and its semi-synthetic derivatives against oral pathogens. Phytotherapy Research, v. 21, n. 5, p. 420-422, .

DA SILVA‚ R.; SARAIVA‚ J.; DE ALBUQUERQUE‚ S.; CURTI‚ C.; DONATE‚ PM; BIANCO‚ TNC; BASTOS‚ JK; SILVA‚ MLA. Trypanocidal structure-activity relationship for cis- and trans-methylpluviatolide. Phytochemistry, v. 69, n. 9, p. 1890-1894, .

SOUZA, VANESSA A. DE; SILVA, ROSANGELA DA; PEREIRA, ANA C.; ROYO, VANESSA DE A.; SARAIVA, JULIANA; MONTANHEIRO, MARISA; SOUZA, GUSTAVO H. B. DE; SILVA FILHO, ADEMAR A. DA; GRANDO, MARCELLA D.; DONATE, PAULO M.; et al. Trypanocidal activity of (-)-cubebin derivatives against free amastigote forms of Trypanosoma cruzi. Bioorganic & Medicinal Chemistry Letters, v. 15, n. 2, p. 303-307, .

Patent applications

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES DE2003635980 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Sérgio de Albuquerque; Gustavo Henrique Bianco de Souza; Jairo Kenupp Bastos; Rosângela Silva - March 2003, 25

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES EP20030709465 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Sérgio de Albuquerque; Gustavo Henrique Bianco de Souza; Jairo Kenupp Bastos; Rosângela Silva - March 2003, 25

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC, TETRAHYDROFURANIC LIGNANS AND THEIR SYNTHETIC AND SEMI-SYNTHETIC DERIVATIVES, THEIR ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES, TOPICAL AND/OR SYSTEMIC FORMULATIONS CONTAINING SAID LIGNANS AND THEIR RESPECTIVE THERAPEUTIC METHOD EP20060721642 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Jairo Kenupp Bastos; Paulo Marcos Donate; Sergio de Albuquerque; Rosangela da Silva - April 2006, 28

PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS  EP20060761026 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Rosângela da Silva; Vanderlei Rodrigues; Olavo dos Santos Pereira Júnior; Ademar Alves da Silva Filho; Paulo Marcos Donate; Sérgio de Albuquerque; Jairo Kenupp Bastos - July 2006, 14

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES JP2011098968 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Sérgio de Albuquerque; Gustavo Henrique Bianco de Souza; Jairo Kenupp Bastos; Rosângela Silva - December 2007, 06

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES PCT/BR2003/000045 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Sérgio de Albuquerque; Gustavo Henrique Bianco de Souza; Jairo Kenupp Bastos; Rosângela Silva - March 2003, 25

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC, TETRAHYDROFURANIC LIGNANS AND THEIR SYNTHETIC AND SEMI-SYNTHETIC DERIVATIVES, THEIR ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES, TOPICAL AND/OR SYSTEMIC FORMULATIONS CONTAINING SAID LIGNANS AND THEIR RESPECTIVE THERAPEUTIC METHOD PCT/BR2006/000084 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Jairo Kenupp Bastos; Paulo Marcos Donate; Sergio de Albuquerque; Rosangela da Silva - April 2006, 28

PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS  PCT/BR2006/000144 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Rosângela da Silva; Vanderlei Rodrigues; Olavo dos Santos Pereira Júnior; Ademar Alves da Silva Filho; Paulo Marcos Donate; Sérgio de Albuquerque; Jairo Kenupp Bastos - July 2006, 14

PROCESSO DE OBTENÇÃO DE LIGNANAS DIBENZILBUTIROLACTÔNICAS, PROCESSO DE OBTENÇÃO DE DERIVADOS SINTÉTICOS DE LIGNANAS OSTENTANDO ATIVIDADES QUIMIOPROFILÁTICA E TERAPÊUTICA ANTICHAGÁSICA PI0201237-5 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Sérgio de Albuquerque; Gustavo Henrique Bianco de Souza; Jairo Kenupp Bastos; Rosângela Silva - March 2002, 25

PROCESSO DE OBTENÇÃO DE LIGNANAS DIBENZILBUTIROLACTÔNICAS, TETRAHIDROFURÂNICAS E DE SEUS DERIVADOS SINTÉTICOS E SEMI-SINTÉTICOS, SUAS ATIVIDADES ANALGÉSICA E ANTIINFLAMATÓRIA, FORMULAÇÕES TÓPICAS E/OU SISTÊMICAS CONTENDO TAIS LIGNANAS E RESPECTIVO MÉTODO TERAPÊUTICO PI0501542-1 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Jairo Kenupp Bastos; Paulo Marcos Donate; Sergio de Albuquerque; Rosangela da Silva - April 2005, 28

PROCESSO DE OBTENÇÃO DE DERIVADOS SINTÉTICOS E SEMI-SINTÉTICOS DE LIGNANAS, SUAS ATIVIDADES ANTIPARASITÁRIAS E RESPECTIVAS FORMULAÇÕES FARMACÊUTICAS, ENGLOBANDO O MÉTODO TERAPÊUTICO UTILIZANDO TAIS LIGNANAS NO TRATAMENTO DE PARASITOSES PI0503951-7 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Rosângela da Silva; Vanderlei Rodrigues; Olavo dos Santos Pereira Júnior; Ademar Alves da Silva Filho; Paulo Marcos Donate; Sérgio de Albuquerque; Jairo Kenupp Bastos - July 2005, 15

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES US10/508,875 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Sérgio de Albuquerque; Gustavo Henrique Bianco de Souza; Jairo Kenupp Bastos; Rosângela Silva - March 2003, 25

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC, TETRAHYDROFURANIC LIGNANS AND THEIR SYNTHETIC AND SEMI-SYNTHETIC DERIVATIVES, THEIR ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES, TOPICAL AND/OR SYSTEMIC FORMULATIONS CONTAINING SAID LIGNANS AND THEIR RESPECTIVE THERAPEUTIC METHOD US11/912,645 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Jairo Kenupp Bastos; Paulo Marcos Donate; Sergio de Albuquerque; Rosangela da Silva - April 2006, 28

PROCESS TO OBTAIN DIBENZYLBUTYROLACTONIC LIGNANS; PROCESS TO OBTAIN SYNTHETIC DERIVATIVES FROM LIGNANES BEARING ANTI-CHAGAS CHEMOPROPHYLACTIC AND THERAPEUTICAL ACTIVITIES US11/951,460 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Sérgio de Albuquerque; Gustavo Henrique Bianco de Souza; Jairo Kenupp Bastos; Rosângela Silva - December 2007, 06

PROCESS TO OBTAIN SYNTHETIC AND SEMI-SYNTHETIC LIGNAN DERIVATIVES, THEIR ANTIPARASITIC ACTIVITIES AND CORRESPONDING PHARMACEUTICAL FORMULATIONS, INCLUDING THE THERAPEUTIC METHOD USING SAID LIGNAN FOR THE TREATMENT OF PARASITOSIS  US11/995,789 - Acef S/A; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP). Márcio Luís Andrade e Silva; Rosângela da Silva; Vanderlei Rodrigues; Olavo dos Santos Pereira Júnior; Ademar Alves da Silva Filho; Paulo Marcos Donate; Sérgio de Albuquerque; Jairo Kenupp Bastos - July 2006, 14

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