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Glaucius Oliva

CV Lattes ORCID


Universidade de São Paulo (USP). Instituto de Física de São Carlos (IFSC)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

GLAUCIUS OLIVA is Full Professor of the University of São Paulo. He studied Physics and Electronics Engineering as an undergraduate of the University of São Paulo and subsequently obtained his PhD in Protein Crystallography and Structural Biology at the University of London in 1988l. His main research interests are structural biology and medicinal chemistry and its application in drug design and discovery, with a particular focus on parasitic infectious tropical diseases that affect the population of Brazil and other developing countries. His work on Chagas disease has led to the discovery of several new inhibitors of parasitic enzymes, promising new drugs for the treatment of this endemic illness. He was the key leader in the establishment of Protein Crystallography research in Brazil, including the development of the first protein crystallography beamline at the Brazilian National Synchrotron Laboratory. He has lead the first graduate program on Biomolecular Physics in the country and more recently created the first undergraduate course on Biomolecular Physical Sciences in Brazil. He was Vice-president of the Brazilian Society of Biochemistry and Molecular Biology-SBBq (2005-2007). Prof. Oliva has lead several projects in collaboration with Brazilian pharmaceutical industries, including programs of biodiversity screening for new natural products drug candidates. Amongst other prizes, he is Member of the Brazilian Academy of Sciences, Member of the National Order of Scientific Merit of Brazil, International Scholar of the Howard Hughes Medical Institute (1997-2001), Member of TWAS (The World Academy of Sciences for the advancement of science in developing countries) and Fellow do Birkbeck College - University of London. He was Director (2010) and President (2011-2015) of the Brazilian National Council for Scientific and Technological Development (CNPq); founder and member of the Governing Board of the Global Research Council (GRC). (Source: Lattes Curriculum)

Articles published in Pesquisa FAPESP Magazine about the researcher:
An agenda for forgotten diseases 
Promising structures 
Estructuras prometedoras 
The essence of molecules 
Pronósticos optimistas 
The essence of molecules 
La esencia de las moléculas 
A promising forecast 
News published in Agência FAPESP Newsletter about the researcher
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Videos related to Research Grants and Scholarships

Structural biology and drug discovery against Zika vírus and other arboviroses

Published by Agência FAPESP - February 12, 2019. We will describe our structural biology studies of Zika virus proteins, including the crystallographic structures of NS5 RNA-dependent RNA polymerase, NS3-helicase and NS3-protease, and the ensuing efforts towards the identification on inhibitors and development of novel antiviral lead candidates. We will also report our current progresses in the structural and functional studies of other arbovirus circulating in Brazil, as yellow fever and chikungunya viruses. Glaucius Oliva | FAPESP Week London.
Patent applications

MODELO TRIDIMENSIONAL PARA REPRESENTAR MOLÉCULA OU PARTE DE MOLÉCULA DE ÁCIDO NUCLÉICO E KIT PI0301512-2 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade de São Paulo (USP). Leila Maria Beltramini; Ana Paula Ulian de Araujo; Luciano Douglas dos Santos Abel - May 2003, 16

METHOD FOR EXTRACTING AND ISOLATING ACTIVE SUBSTANCES FROM UMBU PULP, ACTIVE SUBSTANCES, NUTRACEUTICAL AND/OR FUNCTIONAL FOODS COMPRISING SAID ACTIVE SUBSTANCES AND USES THEREOF PCT/BR2015/050172 - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP). Maria Luiza Zeraik; Emerson Ferreira Queiroz; Ian Castro-Gamboa; Dulce Helena Siqueira Silva; Muriel Cuendet; Laurence Marcourt; Olivier Ciclet; Vanderlan da Silva Bolzani; Jean-Luc Wolfender - October 2015, 07

METHOD FOR EXTRACTING AND ISOLATING ACTIVE SUBSTANCES FROM UMBU PULP, NUTRACEUTICAL AND/OR FUNCTIONAL FOODS AND COSMETICS COMPRISING SAID ACTIVE SUBSTANCES AND USES THEREOF PCT/BR2015/050173 - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP). Maria Luiza Zeraik; Emerson Ferreira Queiroz; Ian Castro-Gamboa; Dulce Helena Siqueira Silva; Muriel Cuendet; Vanderlan da Silva Bolzani; Jean-Luc Wolfender - October 2015, 07

PROCESSO DE OBTENÇÃO DOS PEPTÍDEOS DÍMERICOS DES-CYS11, LYS12, LYS13-(PBTHTXI) K, [TRP3,5] DES-CYS11, LYS12, LYS13-(PBTHTX-I)K E [TRP3,5,10] DES-CYS11, LYS12, LYS13- (PBTHTX-I)K E SEUS USOS COMO ANTIMICROBIANO BR1020180719149 - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP). EDUARDO MAFFUD CILLI ; NORIVAL ALVES SANTOS FILHO ; ILANA LOPES BARATELLA DA CUNHA CAMARGO ; GABRIELA MARINHO RIGHETTO ; THAINA CRISTINA LEAL - October 2018, 24

PEPTÍDEOS SINTÉTICOS, ANÁLOGOS AOS DO FEIJÃO CAUPÍ, COM A ATIVIDADE DE INIBIÇÃO DA ENZIMA HMG-COA REDUTASE BR1020200203100 - Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP); Universidade Federal da Bahia (UFBA). JAFF RIBEIRO DA SILVA ; EDUARDO MAFFUD CILLI ; MARIANA BARROS DE CERQUEIRA E SILVA ; BIANE OLIVEIRA PHILADELPHO ; EDERLAN DE SOUZA FERREIRA ; MARCELO SANTOS CASTILHO ; VICTÓRIA CRUZ DE SOUZA - October 2020, 02

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