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André Gustavo Tempone Cardoso

CV Lattes ResearcherID ORCID


Secretaria da Saúde (São Paulo - Estado). Coordenadoria de Controle de Doenças (CCD). Instituto Adolfo Lutz (IAL)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

Bachelor in Pharmacy & Biochemistry (Oswaldo Cruz College, 1997), master's degree Institute of Energy and Nuclear Research -USP (1999), doctorate in Parasitology (Institute of Biomedical Sciences-USP) (2003) with sandwich period at the London School of Hygiene and Tropical Medicine (with Prof. Simon L. Croft). Post-doctorate at UNIFESP (Physiology). Professor and scientific researcher VI of the Adolfo Lutz Institute (2004-present), coordinator of the Laboratory of Novel Drugs for Neglected Diseases and deputy director of the Parasitology and Mycology Centre. Professor (2006-current) and deputy general coordinator of the Postgraduation Program of the State Department of Health and coordinator of the Laboratory Research in Public Health area. Professor (2010-current) at the postgraduation program of Institute of Tropical Medicine, Faculty of Medicine University of São Paulo. Expertise 1) drugs for infectious diseases, with an emphasis on neglected tropical diseases such as leishmaniasis and Chagas disease; 2) drugs for multidrug-resistant pathogens (ESKAPE); 3) Marine Microbiology with emphasis on the OSMAC approach and isolation of microbial metabolites as pharmaceutical prototypes; 4) in vitro studies of mechanism of action and preclinical in vivo. Coordinate national and international collaborative projects, with UFABC, UNIFESP, USP`, University of Oxford (UK), University of Dundee (UK), University of Southampton (UK), University of Bangor (UK), London School of Hygiene and Tropical Medicine (United Kingdom), Universität Munster (DE), Johannes Gutenberg-University Mainz (DE), Universität Düsseldorf (DE), Ohio State University (USA). Coordinated public-private project with the pharmaceutical company GSK (UK 2011-2014). He is a member (2011-current) of the international research network on natural products for drugs (ResNet NPND- Universität Münster, DE). Editorial Board Member - Infectious Diseases - of the journal Scientific Reports (Nature). Ad hoc advisor of international agencies such as Research Councils (RCUK), Health Research Board (Ireland, United Kingdom), Agence Nationale de la Recherche (ANR-France), Conycit (Argentina), National Science Center (Poland). Production: publications: 112 (index H 28); supervision 10 (master's), 8 (doctorate), postdoctoral: 4 (Source: Lattes Curriculum)

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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (65)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications60
Citations497
Cit./Article8.3
Data from Web of Science

REIMAO, JULIANA Q.; SCOTTI, MARCUS T.; TEMPONE, ANDRE G.. Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study. Bioorganic & Medicinal Chemistry, v. 18, n. 22, p. 8044-8053, . Web of Science Citations: 41. (08/11434-3, 08/09260-7)

PAROLIN, GIOVANA A.; GONCALVES, GIULIA E. G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; CASELI, LUCIANO; LAGO, JOAO HENRIQUE G.; PERES, LAURA O.. Evaluation of the effects in cellular membrane models of antitrypanosomal poly-thymolformaldehyde (PTF) using Langmuir monolayers. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, v. 1863, n. 2, . Web of Science Citations: 0. (18/18180-9, 18/22214-6, 18/10279-6, 19/03239-0, 18/07885-1, 14/50869-6)

ERICK P. DANTAS; JACKSON MONTEIRO; LÍVIA S. DE MEDEIROS; MAIARA M. ROMANELLI; MAIARA AMARAL; ANDRE G. TEMPONE; JOÃO HENRIQUE G. LAGO; MARISI G. SOARES; PATRICIA SARTORELLI. Dereplication of Aporphine Alkaloids by UHPLC-HR-ESI-MS/MS and NMR from Duguetia lanceolata St.-Hit (Annonaceae) and Antiparasitic Activity Evaluation. Journal of the Brazilian Chemical Society, v. 31, n. 9, p. 1908-1916, . Web of Science Citations: 0. (18/10279-6, 16/24985-4)

MESQUITA, JULIANA TONINI; ROMANELLI, MAIARA MARIA; TRINCONI TRINCONI, CRISTIANA DE MELO C. M.; GUERRA, JULIANA MARIOTTI; TANIWAKI, NOEMI NOSOMI; BORTOLIN ULIANA, SILVIA RENI; REIMAO, JULIANA QUERO; TEMPONE, ANDRE GUSTAVO. Repurposing topical triclosan for cutaneous leishmaniasis: Preclinical efficacy in a murineLeishmania (L.) amazonensismodel. Drug Development Research, . Web of Science Citations: 0. (18/10279-6, 15/23403-9)

OLIVEIRA, EMERSON A.; BRITO, IVANILDO A.; LIMA, MARTA L.; ROMANELLI, MAIARA; MOREIRA-FILHO, JOSE T.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; SARTORELLI, PATRICIA; TEMPONE, ANDRE G.; COSTA-SILVA, THAIS A.; et al. Antitrypanosomal Activity of Acetogenins Isolated from the Seeds of Porcelia macrocarpa Is Associated with Alterations in Both Plasma Membrane Electric Potential and Mitochondrial Membrane Potential. Journal of Natural Products, v. 82, n. 5, p. 1177-1182, . Web of Science Citations: 0. (18/10279-6, 18/07885-1)

MENDES, VIVIANE DE MELO; TEMPONE, ANDRE GUSTAVO; TREIGER BORBOREMA, SAMANTA ETEL. Antileishmanial activity of Hi-antihistamine drugs and cellular alterations in Leishmania (L.) infantum. Acta Tropica, v. 195, p. 6-14, . Web of Science Citations: 1. (14/24908-4, 18/10279-6)

UENO, ANDERSON K.; BARCELLOS, ALINE F.; COSTA-SILVA, THAIS A.; MESQUITA, JULIANA T.; FERREIRA, DAIANE D.; TEMPONE, ANDRE G.; ROMOFF, PAULETE; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.. Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae). Fitoterapia, v. 125, p. 55-58, . Web of Science Citations: 7. (15/23403-9, 15/11936-2, 14/08961-2)

ROMANELLI, MAIARA MARIA; DA COSTA-SILVA, THAIS ALVES; CUNHA-JUNIOR, EDEZIO; DIAS FERREIRA, DAIANE; GUERRA, JULIANA M.; GALISTEO, JR., ANDRES JIMENEZ; PINTO, ERIKA GRACIELLE; BARBOSA, LEANDRO R. S.; TORRES-SANTOS, EDUARDO CAIO; TEMPONE, ANDRE GUSTAVO. Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v. 9, . Web of Science Citations: 0. (18/10279-6, 15/15822-1, 13/07275-5, 15/23403-9)

VARELA, MARINA T.; ROMANELI, MAIARA M.; LIMA, MARTA L.; BORBOREMA, SAMANTA E. T.; TEMPONE, ANDRE G.; FERNANDES, JOAO P. S.. Antiparasitic activity of new gibbilimbol analogues and SAR analysis through efficiency and statistical methods. European Journal of Pharmaceutical Sciences, v. 122, p. 31-41, . Web of Science Citations: 4. (15/23403-9, 16/25028-3, 16/00195-4)

WULSTEN, IMKE E.; COSTA-SILVA, THAIS A.; MESQUITA, JULIANA T.; LIMA, MARTA L.; GALUPPO, MARIANA K.; TANIWAKI, NOEMI N.; BORBOREMA, SAMANTA E. T.; DA COSTA, FERNANDO B.; SCHMIDT, THOMAS J.; TEMPONE, ANDRE G.. Investigation of the Anti-Leishmania (Leishmania) infantum Activity of Some Natural Sesquiterpene Lactones. Molecules, v. 22, n. 5, . Web of Science Citations: 9. (13/50228-8, 12/18756-1)

BARBOSA, HENRIQUE; DA SILVA, RAFAEL LEONARDO C. G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.; CASELI, LUCIANO. Interaction of dicentrinone, an antitrypanosomal aporphine alkaloid isolated from Ocotea puberula (Lauraceae), in cell membrane models at the air-water interface. BIOORGANIC CHEMISTRY, v. 101, . Web of Science Citations: 0. (19/03239-0, 18/00291-9, 18/10279-6, 18/07885-1)

MORAIS, THIAGO R.; ALVES CONSERVA, GEANNE A.; VARELA, MARINA T.; COSTA-SILVA, THAIS A.; THEVENARD, FERNANDA; PONCI, VITOR; FORTUNA, ANA; FALCAO, AMILCAR C.; TEMPONE, ANDRE G.; FERNANDES, JOAO PAULO S.; et al. Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A. SCIENTIFIC REPORTS, v. 10, n. 1, . Web of Science Citations: 2. (16/20633-6, 18/07885-1, 18/10279-6, 16/25028-3)

OLIVEIRA, LIDIANE; FERRARINI, MARCIO; DOS SANTOS, ALEXANDRE PAES; VARELA, MARINA THEMOTEO; SANTOS CORREA, ISABELA TERESA; TEMPONE, ANDRE GUSTAVO; MELHEM, MARCIA S. C.; VALLIM, MARCELO A.; FERNANDES, JOAO PAULO S.; PASCON, RENATA C.. Coumaric acid analogues inhibit growth and melanin biosynthesis in Cryptococcus neoformans and potentialize amphotericin B antifungal activity. European Journal of Pharmaceutical Sciences, v. 153, . Web of Science Citations: 0. (16/25028-3, 18/10279-6, 16/14542-8, 15/04400-9, 18/03918-2)

IVANILDO A. BRITO; EMERSON A. OLIVEIRA; MARIANA H. CHAVES; FERNANDA THEVENARD; ANDRÉ F. RODRIGUES-OLIVEIRA; GUSTAVO BARBOSA-REIS; PATRICIA SARTORELLI; DIOGO OLIVEIRA-SILVA; ANDRE G. TEMPONE; THAIS A. COSTA-SILVA; et al. Antileishmanial Acetylene Fatty Acid and Acetogenins from Seeds of Porcelia macrocarpa. Journal of the Brazilian Chemical Society, v. 32, n. 2, p. 447-453, . (18/07885-1, 18/10279-6)

BRITO, JULIANA R.; DA COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; FERREIRA, EDGARD A.; LAGO, JOAO HENRIQUE G.. Dibenzylbutane neolignans from Saururus cernuus L. (Saururaceae) displayed anti-Trypanosoma cruzi activity via alterations in the mitochondrial membrane potential. Fitoterapia, v. 137, . Web of Science Citations: 0. (18/10279-6, 18/07885-1)

DA COSTA-SILVA, THAIS A.; ALVES CONSERVA, GEANNE A.; GALISTEO, JR., ANDRES J.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae). Journal of Venomous Animals and Toxins including Tropical Diseases, v. 25, . Web of Science Citations: 0. (16/20633-6, 18/10279-6, 18/07885-1)

SILVA, ARMENIO A. DE CARVALHO A. DA; SOUSA, ELCILENE A. DE; VERAS, MARCIA D. ALVES; ARAUJO, BRUNO Q.; THEVENARD, FERNANDA; LAGO, JOAO HENRIQUE G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; CHAVES, MARIANA H.. In vitro anti-Trypanosoma cruzi evaluation of sesquiterpenes from the branches of Oxandra sessiliflora. PHYTOCHEMISTRY LETTERS, v. 37, p. 59-62, . Web of Science Citations: 0. (18/10279-6, 18/07885-1)

ALVES CONSERVA, GEANNE A.; DA COSTA-SILVA, THAIS A.; AMARAL, MAIARA; ANTAR, GUILHERME M.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria. Phytomedicine, v. 54, p. 302-307, . Web of Science Citations: 1. (15/23403-9, 16/20633-6, 18/07885-1)

GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; JERZ, GEROLD; DE SOUSA, FERNANDA S.; LONDERO, VINICIUS S.; GALUPPO, MARIANA K.; LIMA, MARTA L.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; et al. Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages. Chemico-Biological Interactions, v. 277, p. 55-61, . Web of Science Citations: 8. (15/50075-2, 13/50228-8, 15/11936-2)

AMARAL, MAIARA; DE SOUSA, FERNANDA S.; SILVA, THAIS A. COSTA; JUNIOR, ANDRES JIMENEZ G.; TANIWAKI, NOEMI N.; JOHNS, DEID RE M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; TEMPONE, ANDRE G.. A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division. SCIENTIFIC REPORTS, v. 9, . Web of Science Citations: 3. (15/50075-2, 18/10279-6, 18/07885-1)

CORREA, ISABELA TERESA SANTOS; DA COSTA-SILVA, THAIS ALVES; TEMPONE, ANDRE GUSTAVO. Bioenergetics impairment of Trypanosoma cruzi by the antihypertensive manidipine: A drug repurposing strategy. Acta Tropica, v. 214, . Web of Science Citations: 0. (18/10279-6)

PIEPER, PAULINE; MCHUGH, ELIZA; AMARAL, MAIARA; TEMPONE, ANDRE G.; ANDERSON, EDWARD A.. Enantioselective synthesis and anti-parasitic properties of aporphine natural products. Tetrahedron, v. 76, n. 2, SI, . Web of Science Citations: 0. (18/10279-6, 18/25128-3)

DA COSTA-SILVA, THAIS A.; ALVES CONSERVA, GEANNE A.; GALISTEO, JR., ANDRES J.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae). Journal of Venomous Animals and Toxins including Tropical Diseases, v. 25, . Web of Science Citations: 0. (16/20633-6, 18/10279-6, 18/07885-1)

TEMPONE, ANDRE G.; PIEPER, PAULINE; BORBOREMA, SAMANTA E. T.; THEVENARD, FERNANDA; LAGO, JOAO HENRIQUE G.; CROFT, SIMON L.; ANDERSON, EDWARD A.. Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria. NATURAL PRODUCT REPORTS, . Web of Science Citations: 0. (19/10434-4, 18/07885-1, 18/10279-6)

PINTO, ERIKA GRACIELLE; BARBOSA, LEANDRO R. S.; MORTARA, RENATO A.; TEMPONE, ANDRE GUSTAVO. Targeting intracellular Leishmania (L.) infantum with nitazoxanide entrapped into phosphatidylserine-nanoliposomes: An experimental study. Chemico-Biological Interactions, v. 332, . Web of Science Citations: 0. (18/10279-6)

ALVES CONSERVA, GEANNE A.; DA COSTA-SILVA, THAIS A.; AMARAL, MAIARA; ANTAR, GUILHERME M.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria. Phytomedicine, v. 54, p. 302-307, . Web of Science Citations: 1. (15/23403-9, 18/07885-1, 16/20633-6)

GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; JERZ, GEROLD; DE SOUSA, FERNANDA S.; LONDERO, VINICIUS S.; GALUPPO, MARIANA K.; LIMA, MARTA L.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; et al. Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages. Chemico-Biological Interactions, v. 277, p. 55-61, . Web of Science Citations: 8. (15/50075-2, 13/50228-8, 15/11936-2)

AMARAL, MAIARA; DE SOUSA, FERNANDA S.; SILVA, THAIS A. COSTA; JUNIOR, ANDRES JIMENEZ G.; TANIWAKI, NOEMI N.; JOHNS, DEID RE M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; TEMPONE, ANDRE G.. A semi-synthetic neolignan derivative from dihydrodieugenol B selectively affects the bioenergetic system of Leishmania infantum and inhibits cell division. SCIENTIFIC REPORTS, v. 9, . Web of Science Citations: 3. (15/50075-2, 18/07885-1, 18/10279-6)

ERIKA G. PINTO; ANDRE G. TEMPONE. Activity of the antiarrhythmic drug amiodarone against Leishmania (L.) infantum: an in vitro and in vivo approach. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 24, p. -, . (15/23403-9)

FERREIRA, DAIANE D.; SOUSA, FERNANDA S.; COSTA-SILVA, THAIS A.; REIMAO, JULIANA Q.; TORRECILHAS, ANA C.; JOHNS, DEIDRE M.; SEAR, CLAIRE E.; HONORIO, KATHIA M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; et al. Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 176, p. 162-174, . Web of Science Citations: 2. (15/50075-2, 18/07885-1, 18/10279-6, 16/24524-7)

CUNHA-JUNIOR, EDEZIO FERREIRA; ANDRADE-NETO, VALTER VIANA; LIMA, MARTA LOPES; DA COSTA-SILVA, THAIS ALVES; GALISTEO JUNIOR, ANDRES J.; ABENGOZAR, MARIA A.; BARBAS, CORAL; RIVAS, LUIS; ALMEIDA-AMARAL, ELMO EDUARDO; TEMPONE, ANDRE GUSTAVO; et al. Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice. PLoS Neglected Tropical Diseases, v. 11, n. 1, . Web of Science Citations: 7. (15/23403-9)

GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; SOUSA, FERNANDA S.; CARGNELUTTI, STEFANO B.; UMEHARA, ERIC; MENDONCA, POLIANA S.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Neolignans isolated from twigs of Nectandra leucantha Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 24, . Web of Science Citations: 0. (18/07885-1, 15/23403-9)

SILVA, ARMENIO A. DE CARVALHO A. DA; SOUSA, ELCILENE A. DE; VERAS, MARCIA D. ALVES; ARAUJO, BRUNO Q.; THEVENARD, FERNANDA; LAGO, JOAO HENRIQUE G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; CHAVES, MARIANA H.. In vitro anti-Trypanosoma cruzi evaluation of sesquiterpenes from the branches of Oxandra sessiliflora. PHYTOCHEMISTRY LETTERS, v. 37, p. 59-62, . Web of Science Citations: 1. (18/07885-1, 18/10279-6)

VARELA, MARINA T.; COSTA-SILVA, THAIS A.; LAGO, JOAO HENRIQUE G.; TEMPONE, ANDRE G.; FERNANDES, JOAO PAULO S.. Evaluation of the antitrypanosoma activity and SAR study of novel LINS03 derivatives. BIOORGANIC CHEMISTRY, v. 89, . Web of Science Citations: 0. (18/03918-2, 16/25028-3, 18/07885-1, 15/23403-9)

VARELA, MARINA T.; LIMA, MARTA L.; GALUPPO, MARIANA K.; TEMPONE, ANDRE G.; DE OLIVEIRA, ALBERTO; LAGO, JOAO HENRIQUE G.; FERNANDES, JOAO PAULO S.. New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum. CHEMICAL BIOLOGY & DRUG DESIGN, v. 90, n. 5, p. 1007-1011, . Web of Science Citations: 8. (16/00195-4, 13/50228-8, 12/18756-1, 15/11936-2)

REIMAO, JULIANA Q.; SCOTTI, MARCUS T.; TEMPONE, ANDRE G.. Anti-leishmanial and anti-trypanosomal activities of 1,4-dihydropyridines: In vitro evaluation and structure-activity relationship study. Bioorganic & Medicinal Chemistry, v. 18, n. 22, p. 8044-8053, . Web of Science Citations: 41. (08/11434-3, 08/09260-7)

PAROLIN, GIOVANA A.; GONCALVES, GIULIA E. G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; CASELI, LUCIANO; LAGO, JOAO HENRIQUE G.; PERES, LAURA O.. Evaluation of the effects in cellular membrane models of antitrypanosomal poly-thymolformaldehyde (PTF) using Langmuir monolayers. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, v. 1863, n. 2, . Web of Science Citations: 0. (18/18180-9, 19/03239-0, 14/50869-6, 18/07885-1, 18/22214-6, 18/10279-6)

UMEHARA, ERIC; SILVA, THAIS A. COSTA; MENDES, VIVIANE M.; GUADAGNIN, RAFAEL C.; SARTORELLI, PATRICIA; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Differential lethal action of C17:2 and C17:0 anacardic acid derivatives in Trypanosoma cruzi - A mechanistic study. BIOORGANIC CHEMISTRY, v. 102, . Web of Science Citations: 0. (18/10279-6, 18/07885-1)

ALVES CONSERVA, GEANNE A.; QUIROS-GUERRERO, LUIS M.; COSTA-SILVA, THAIS A.; MARCOURT, LAURENCE; PINTO, ERIKA G.; TEMPONE, ANDRE G.; FERNANDES, JOAO PAULO S.; WOLFENDER, JEAN-LUC; QUEIROZ, EMERSON F.; LAGO, JOAO HENRIQUE G.. Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses. PLoS One, v. 16, n. 2, . Web of Science Citations: 1. (15/23403-9, 18/18975-1, 16/20633-6, 18/10279-6, 18/07885-1)

LONDERO, VINICIUS S.; COSTA-SILVA, THAIS A.; ANTAR, GUILHERME M.; BAITELLO, JOAO B.; DE OLIVEIRA, LARISSA V. F.; CAMILO, FERNANDA F.; BATISTA, ANDREA N. L.; BATISTA, JR., JOAO M.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Antitrypanosomal Lactones from Nectandra barbellata. Journal of Natural Products, v. 84, n. 5, p. 1489-1497, . Web of Science Citations: 1. (21/02789-7, 14/25222-9, 17/17044-1, 18/10279-6, 18/07885-1)

SEAR, CLAIRE E.; PIEPER, PAULINE; AMARAL, MAIARA; ROMANELLI, MAIARA M.; COSTA-SILVA, THAIS A.; HAUGLAND, MARIUS M.; TATE, JOSEPH A.; LAGO, JOAO H. G.; TEMPONE, ANDRE G.; ANDERSON, EDWARD A.. Synthesis and Structure-Activity Relationship of Dehydrodieugenol B Neolignans against Trypanosoma cruzi. ACS INFECTIOUS DISEASES, v. 6, n. 11, p. 2872-2878, . Web of Science Citations: 0. (18/25128-3, 18/10279-6)

LONDERO, VINICIUS S.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; NAMIYAMA, GISLENE M.; THEVENARD, FERNANDA; ANTAR, GUILHERME M.; BAITELLO, JOAO B.; LAGO, JOAO HENRIQUE G.. Anti-Trypanosoma cruzi activity of costic acid isolated from Nectandra barbellata (Lauraceae) is associated with alterations in plasma membrane electric and mitochondrial membrane potentials. BIOORGANIC CHEMISTRY, v. 95, . Web of Science Citations: 0. (18/10279-6, 17/17044-1, 18/07885-1)

OLIVEIRA, EMERSON A.; BRITO, IVANILDO A.; LIMA, MARTA L.; ROMANELLI, MAIARA; MOREIRA-FILHO, JOSE T.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; SARTORELLI, PATRICIA; TEMPONE, ANDRE G.; COSTA-SILVA, THAIS A.; et al. Antitrypanosomal Activity of Acetogenins Isolated from the Seeds of Porcelia macrocarpa Is Associated with Alterations in Both Plasma Membrane Electric Potential and Mitochondrial Membrane Potential. Journal of Natural Products, v. 82, n. 5, p. 1177-1182, . Web of Science Citations: 0. (18/10279-6, 18/07885-1)

MENDES, VIVIANE DE MELO; TEMPONE, ANDRE GUSTAVO; TREIGER BORBOREMA, SAMANTA ETEL. Antileishmanial activity of Hi-antihistamine drugs and cellular alterations in Leishmania (L.) infantum. Acta Tropica, v. 195, p. 6-14, . Web of Science Citations: 1. (14/24908-4, 18/10279-6)

UENO, ANDERSON K.; BARCELLOS, ALINE F.; COSTA-SILVA, THAIS A.; MESQUITA, JULIANA T.; FERREIRA, DAIANE D.; TEMPONE, ANDRE G.; ROMOFF, PAULETE; ANTAR, GUILHERME M.; LAGO, JOAO HENRIQUE G.. Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae). Fitoterapia, v. 125, p. 55-58, . Web of Science Citations: 7. (15/23403-9, 15/11936-2, 14/08961-2)

ROMANELLI, MAIARA MARIA; DA COSTA-SILVA, THAIS ALVES; CUNHA-JUNIOR, EDEZIO; DIAS FERREIRA, DAIANE; GUERRA, JULIANA M.; GALISTEO, JR., ANDRES JIMENEZ; PINTO, ERIKA GRACIELLE; BARBOSA, LEANDRO R. S.; TORRES-SANTOS, EDUARDO CAIO; TEMPONE, ANDRE GUSTAVO. Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, v. 9, . Web of Science Citations: 0. (18/10279-6, 15/15822-1, 13/07275-5, 15/23403-9)

WULSTEN, IMKE E.; COSTA-SILVA, THAIS A.; MESQUITA, JULIANA T.; LIMA, MARTA L.; GALUPPO, MARIANA K.; TANIWAKI, NOEMI N.; BORBOREMA, SAMANTA E. T.; DA COSTA, FERNANDO B.; SCHMIDT, THOMAS J.; TEMPONE, ANDRE G.. Investigation of the Anti-Leishmania (Leishmania) infantum Activity of Some Natural Sesquiterpene Lactones. Molecules, v. 22, n. 5, . Web of Science Citations: 9. (13/50228-8, 12/18756-1)

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LONDERO, VINICIUS S.; DA COSTA-SILVA, THAIS A.; GOMES, KAIO S.; FERREIRA, DAIANE D.; MESQUITA, JULIANA T.; TEMPONE, ANDRE G.; YOUNG, MARIA CLAUDIA M.; JERZ, GEROLD; LAGO, JOAO HENRIQUE G.. Acetylenic fatty acids from Porcelia macrocarpa (Annonaceae) against trypomastigotes of Trypanosoma cruzi: Effect of octadec-9-ynoic acid in plasma membrane electric potential. BIOORGANIC CHEMISTRY, v. 78, p. 307-311, . Web of Science Citations: 3. (15/23403-9)

GOMES, KAIO S.; DA COSTA-SILVA, THAIS A.; OLIVEIRA, IGOR H.; AGUILAR, ANDREA M.; OLIVEIRA-SILVA, DIOGO; UEMI, MIRIAM; SILVA, WENDER A.; MELO, LENNINE R.; ANDRADE, CARLOS KLEBER Z.; TEMPONE, ANDRE G.; et al. Structure-activity relationship study of antitrypanosomal chalcone derivatives using multivariate analysis. Bioorganic & Medicinal Chemistry Letters, v. 29, n. 12, p. 1459-1462, . Web of Science Citations: 0. (18/10279-6, 18/07885-1)

TEMPONE, ANDRE G.; PIEPER, PAULINE; BORBOREMA, SAMANTA E. T.; THEVENARD, FERNANDA; LAGO, JOAO HENRIQUE G.; CROFT, SIMON L.; ANDERSON, EDWARD A.. Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria. NATURAL PRODUCT REPORTS, . Web of Science Citations: 0. (19/10434-4, 18/07885-1, 18/10279-6)

PINTO, ERIKA GRACIELLE; BARBOSA, LEANDRO R. S.; MORTARA, RENATO A.; TEMPONE, ANDRE GUSTAVO. Targeting intracellular Leishmania (L.) infantum with nitazoxanide entrapped into phosphatidylserine-nanoliposomes: An experimental study. Chemico-Biological Interactions, v. 332, . Web of Science Citations: 0. (18/10279-6)

ALVES CONSERVA, GEANNE A.; DA COSTA-SILVA, THAIS A.; AMARAL, MAIARA; ANTAR, GUILHERME M.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria. Phytomedicine, v. 54, p. 302-307, . Web of Science Citations: 1. (15/23403-9, 18/07885-1, 16/20633-6)

GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; JERZ, GEROLD; DE SOUSA, FERNANDA S.; LONDERO, VINICIUS S.; GALUPPO, MARIANA K.; LIMA, MARTA L.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; TEMPONE, ANDRE G.; et al. Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages. Chemico-Biological Interactions, v. 277, p. 55-61, . Web of Science Citations: 8. (15/50075-2, 13/50228-8, 15/11936-2)

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ERIKA G. PINTO; ANDRE G. TEMPONE. Activity of the antiarrhythmic drug amiodarone against Leishmania (L.) infantum: an in vitro and in vivo approach. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 24, p. -, . (15/23403-9)

FERREIRA, DAIANE D.; SOUSA, FERNANDA S.; COSTA-SILVA, THAIS A.; REIMAO, JULIANA Q.; TORRECILHAS, ANA C.; JOHNS, DEIDRE M.; SEAR, CLAIRE E.; HONORIO, KATHIA M.; LAGO, JOAO HENRIQUE G.; ANDERSON, EDWARD A.; et al. Dehydrodieugenol B derivatives as antiparasitic agents: Synthesis and biological activity against Trypanosoma cruzi. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 176, p. 162-174, . Web of Science Citations: 2. (15/50075-2, 18/07885-1, 18/10279-6, 16/24524-7)

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GRECCO, SIMONE S.; COSTA-SILVA, THAIS A.; SOUSA, FERNANDA S.; CARGNELUTTI, STEFANO B.; UMEHARA, ERIC; MENDONCA, POLIANA S.; TEMPONE, ANDRE G.; LAGO, JOAO HENRIQUE G.. Neolignans isolated from twigs of Nectandra leucantha Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity. Journal of Venomous Animals and Toxins including Tropical Diseases, v. 24, . Web of Science Citations: 0. (18/07885-1, 15/23403-9)

SILVA, ARMENIO A. DE CARVALHO A. DA; SOUSA, ELCILENE A. DE; VERAS, MARCIA D. ALVES; ARAUJO, BRUNO Q.; THEVENARD, FERNANDA; LAGO, JOAO HENRIQUE G.; COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; CHAVES, MARIANA H.. In vitro anti-Trypanosoma cruzi evaluation of sesquiterpenes from the branches of Oxandra sessiliflora. PHYTOCHEMISTRY LETTERS, v. 37, p. 59-62, . Web of Science Citations: 1. (18/07885-1, 18/10279-6)

TEMPONE, ANDRE GUSTAVO; PIMENTA, DANIEL CARVALHO; LEBRUN, IVO; SARTORELLI, PATRICIA; TANIWAKI, NOEMI N.; DE ANDRADE, JR., HEITOR FRANCO; ANTONIAZZI, MARTA MARIA; JARED, CARLOS. Antileishmanial and antitrypanosomal activity of bufadienolides isolated from the toad Rhinella jimi parotoid macrogland secretion. Toxicon, v. 52, n. 1, p. 13-21, . Web of Science Citations: 68. (05/00974-9)

MARTINS, LIGIA F.; MESQUITA, JULIANA T.; PINTO, ERIKA G.; COSTA-SILVA, THAIS A.; BORBOREMA, SAMANTA E. T.; GALISTEO JUNIOR, ANDRES J.; NEVES, BRUNO J.; ANDRADE, CAROLINA H.; AL SHUHAIB, ZAINAB; BENNETT, ELLIOT L.; et al. Analogues of Marine Guanidine Alkaloids Are in Vitro Effective against Trypanosoma cruzi and Selectively Eliminate Leishmania (L.) infantum Intracellular Amastigotes. Journal of Natural Products, v. 79, n. 9, p. 2202-2210, . Web of Science Citations: 15. (11/23703-1, 13/07275-5, 13/50228-8, 12/18756-1)

MORAIS, THIAGO R.; DA COSTA-SILVA, THAIS A.; TEMPONE, ANDRE G.; BORBOREMA, SAMANTA ETEL T.; SCOTTI, MARCUS T.; DE SOUSA, RAQUEL MARIA F.; ARAUJO, ANA CAROLINA C.; DE OLIVEIRA, ALBERTO; DE MORAIS, SERGIO ANTONIO L.; SARTORELLI, PATRICIA; et al. Antiparasitic Activity of Natural and Semi-Synthetic Tirucallane Triterpenoids from Schinus terebinthifolius (Anacardiaceae): Structure/Activity Relationships. Molecules, v. 19, n. 5, p. 5761-5776, . Web of Science Citations: 8. (11/51739-0, 12/18756-1, 13/16320-4)

ERICK P. DANTAS; JACKSON MONTEIRO; LÍVIA S. DE MEDEIROS; MAIARA M. ROMANELLI; MAIARA AMARAL; ANDRE G. TEMPONE; JOÃO HENRIQUE G. LAGO; MARISI G. SOARES; PATRICIA SARTORELLI. Dereplication of Aporphine Alkaloids by UHPLC-HR-ESI-MS/MS and NMR from Duguetia lanceolata St.-Hit (Annonaceae) and Antiparasitic Activity Evaluation. Journal of the Brazilian Chemical Society, v. 31, n. 9, p. 1908-1916, . Web of Science Citations: 0. (18/10279-6, 16/24985-4)

MESQUITA, JULIANA TONINI; ROMANELLI, MAIARA MARIA; TRINCONI TRINCONI, CRISTIANA DE MELO C. M.; GUERRA, JULIANA MARIOTTI; TANIWAKI, NOEMI NOSOMI; BORTOLIN ULIANA, SILVIA RENI; REIMAO, JULIANA QUERO; TEMPONE, ANDRE GUSTAVO. Repurposing topical triclosan for cutaneous leishmaniasis: Preclinical efficacy in a murineLeishmania (L.) amazonensismodel. Drug Development Research, . Web of Science Citations: 0. (18/10279-6, 15/23403-9)

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