graduate at Medicina Veterinária from Universidade Paulista (1994), master's at Veterinary Medicine from Universidade de São Paulo (1999) and ph.d. at Veterinary Medicine from Universidade de São Paulo (2003). Currently is Associate Professor at Scholl Veterinary Medicine of Sao Paulo University. Has experience in Immunology, focusing on Immunology, acting on the following subjects: flow cytometry, burst oxidative, midazolam, vacina anti-tumoral and macrophage. He is a research leader at the Laboratory of Comparative Immuno-oncology (LionC) assigned to the Department of Pathology - FMVZ. Member of Veterinary Comparative Clinical Immunology Society. CNPQ Productivity Scholarship - PQ-2 (CNPq No. 4/2021) (Source: Lattes Curriculum)
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This project aims to verify the clinical outcome of an experimental immunotherapy associated with conventional treatments used in veterinary oncology and to evaluate the influence of the immunological context represented by an "immunogram" as a predictive factor in the clinical response of dogs with solid neoplasia. It will be based on a prospective clinical safety study comparing surviva…
The tumor microenvironment consists of various cell types, including cells of the immune system. In particular, dendritic cells (DCs) have been widely studied in the tumor microenvironment, since these cells are considered the most potent antigen presenting cells (APCs) and are responsible for coordinating the adaptive immune response and play a key role in inducing and maintaining the an…
(Only some records are available in English at this moment)
Oral inflammatory diseases in cats are common and generally associated with a serious decline in quality of life and systemic repercussions beyond the oral cavity. In domestic cats, three main conditions occur frequently: periodontal disease, affecting almost all adult cats; feline chronic gingivostomatitis, described by ineffective treatments and relapses; and the feline tooth resorption…
Immunotherapy has been an important target of study in the fight against cancer, both in humans and animals, generating a growing need for understanding the interaction between tumor cells and the immune system. In this context, the project aims to evaluate the effect of Indoleamine 2,3-dioxygenase (IDO) expression in canine melanocytic tumor cells on the polarization of macrophages deriv…
The polyriboinosinic-polyribocytidylic acid (Poly-ICLC), also known as Hiltonol®, is a double-stranded RNA macromolecule that has demonstrated versatility in modulating the immune profile of humans in response to pathogens, both as initial therapy and as a complement in various diseases, including autoimmune, neoplastic, and infectiousdiseases. Its ability to induce type 1 interferons (IF…
The systemic inflammation response index (SIRI) and the neutrophil-lymphocyte, monocyte and platelet ratio were identified as hematological indices that simultaneously reflect the inflammatory and immunological status of cancer patients. This type of analysis is already used in human medicine, but little explored in veterinary medicine. Inflammatory occurrence, which plays a central role …
Neutrophils are a cell population known mainly for their important participation as phagocytes in infectious, inflammatory, and healing processes. In the cancer scenario, a new perspective about the action of this cell type has emerged, since the traditional idea that neutrophils are inert agents is being revisited. Evidence indicates that tumors can recruit neutrophils through the secret…
In the treatment of chronic pain in domestic animals, such as osteoarthrosis, nonsteroidal anti-inflammatory drugs (NSAIDs) are the first line of pharmacological treatment usually associated with analgesics. The mechanism of action of these drugs is still being explored, while the best known is through the inhibition of cyclooxygenase(COX), an essential enzyme for the production of eicosa…
(Only some records are available in English at this moment)
| 4 / 4 | Completed research grants |
| 3 / 3 | Ongoing scholarships in Brazil |
| 13 / 10 | Completed scholarships in Brazil |
| 20 / 17 | All research grants and scholarships |
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CV Lattes
ORCID