CV Lattes
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Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Biológicas e da Saúde (CCBS) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Fisioterapia from Universidade Federal de São Carlos (1983), master's at Psychobiology from Universidade de São Paulo (1988) and Ph.D. at Psychology from Universidade de São Paulo (1992). Has experience in Physiotherapy and Psychobiology, acting on the following subjects: Learning, Emotional Memory, Histamine, Functional Recovery and Gait. (Source: Lattes Curriculum)
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The aim of this study is to investigate the effects of the histaminergic H4 agonist VUF-8430 microinjections into the cerebellar vermis in mice subjected to the elavated plus maze (EPM), inhibitory avoidance (IA) and Rotarod test in the consolidation of emotional memory and the motor control. After surgical recovery from the procedure to implant a cannula, the animals will receive saline …
Experimental evidences indicate that the role of the cerebellum may be more complex than the simple regulation of motor responses. Recent studies have demonstrated significant involvement of the cerebellum in the consolidation of emotional memory. The aim of this study is to investigate the actions of the cerebellar histaminergic neural system in the consolidation of emotional memory in m…
The Neuroscience Laboratory of the Federal University of S. Carlos has carried through some research with contradictory results on the performance of the histaminergic system in the learning processes and memory in fish. Recently, Faganello and Mattioli (2006) studied the effect of the CPA in fish after telencephalic ablation, using an associative task with food. In this study they verifi…
(Only some records are available in English at this moment)
Experimental evidence indicates that the cerebellum is involved in motor and non-motor functions. Since our recent results have demonstrated the participation of the cerebellar histaminergic system in the consolidation of emotional memory, this study aims to investigate the role of the histaminergic neural system in motor learning of mice via cerebellar vermis and establish a possible int…
This study investigates the effect of histaminergic H4 agonist microinjection (VUF-8430) in the consolidation of emotional memory in mice submitted to the elevated plus maze (EPM) and the inhibitory avoidance test (IA) as well as in motor control in mice submitted to the Rotarod test. On the fourth day after surgical recovery from the procedure to implant a cannula, the animals will recei…
The aim of the present study is to investigate the influence of neural histamine in learned helplessness, emotional memory and neurogenesis of mice. Therefore, animals should be subjected to the chronic variable stress (CVS) for 7 days. During that period, the treated animals Will receive systemic injections of imipramine (10 mg/kg) or L-histidine (200 and 500 mg/kg) by volume of 2 ml/kg.…
(Only some records are available in English at this moment)
Carbonic anhydrases (CAs, EC 4.2.1.1) catalyse the interconversion between CO2 and bicarbonate as well as other hydrolytic reactions. At least 16 different alpha-CA isoforms were isolated in mammals, where these enzymes play crucial physiological roles such as pH regulation, CO2 and HCO3 transport, bone resorption, gluconeogenesis, ureagenesis and lipogenesis. In addition some studies sug…
Recently, transgenic mice expressing (A beta)4-42 peptide (Tg4-42 transgenic line) have been generated (Bouter et al., 2013) as a transgenic mouse model of Alzheimer's disease (AD). These mutants developed a massive CA1 pyramidal neuron loss in the hippocampus. This hippocampal neurodegeneration was associated with age-dependent spatial learning deficits in the Morris water-maze. In the p…
Several authors have been investigated and demonstrated that the histaminergic system of the central nervous system influences directly or indirectly (through interaction with other neurotransmitters) mnemonic process. One of these interactions occurs with acetylcholine, and there is clear evidence indicating that histamine controls the release of central acetylcholine locally in the cort…
| 7 / 4 | Completed research grants |
| 25 / 15 | Completed scholarships in Brazil |
| 4 / 3 | Completed scholarships abroad |
| 36 / 22 | All research grants and scholarships |
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