Abstract
PORTION OF RESERVE FOR TECHNICAL INFRASTRUCTURE COSTS INSTITUCIONAL SEARCH - YEAR 2022. (AU)
Graduated in Medicine at the Faculty of Medicine of Jundiaí (1979), specialization in Medicine from the University of São Paulo (1983), Master in Clinical Medicine from the State University of Campinas (1987), Doctorate in Clinical Medicine from the State University of Campinas (1989) ), Post-doctorate from Elizabeth Hospital of Boston Tufts University (1991), Beth Israel Hospital Harvard University (1992), and Laboratoire de therapie génique Hôpital St Louis-Paris INSERME (1999). He is currently Full Professor of the Discipline of Hematology at the State University of Campinas. He began his career in the clinical and molecular investigation of chronic anemias, including hereditary anemias such as sickle cell disease, pyruvate kinase deficiency and glucose-6-phosphate dehydrogenase, spherocytosis and ellipocytosis, among others; and acquired anemias such as myelodysplasias, deficiency anemias and aplastic anemia. Over the past 20 years, she has also investigated the relationship between hematopoietic stem cells and bone marrow niches in animal and human models and recently developed a line of research that investigates new therapeutic targets in hematological neoplasms. Author of more than 350 scientific articles in specialized journals, with a strong presence in the training of human resources, the vast majority of the graduates are successful researchers in Brazil and the United States. More than 200 supervised master?s, doctoral, scientific trainees, post-doctoral students, resident doctors and recent graduates in technical training. In recognition, she has received several national and international awards, notably the SCOPUS 2010 award and the commendation of the order of national scientific merit in 2018. He also works in the diagnosis and treatment of patients with anemias, especially those with hereditary diseases, and in committees technicians from the health department of the State of São Paulo and the Ministry of Health. Elected member of the Brazilian Academy of Sciences (ABC) since 2010. (Source: Lattes Curriculum)
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PORTION OF RESERVE FOR TECHNICAL INFRASTRUCTURE COSTS INSTITUCIONAL SEARCH - YEAR 2022. (AU)
Bone marrow neoplasias are aggressive disorders with low healing potential. As the incidence of cancer increases with age, a growing number of older individuals are receiving therapy for cancer and frequently in intensive modalities. As these older patients tend to present comorbidities, treatment decisions can often become difficult due to their fragile physical state which may affect th…
Application of the portion for institutional infrastructure costs for the acquisition of air conditioners (permanent material). (AU)
PORTION OF RESERVE FOR TECHNICAL INFRASTRUCTURE COSTS INSTITUCIONAL SEARCH - YEAR 2019 (AU)
PORTION OF RESERVE FOR TECHNICAL INFRASTRUCTURE COSTS INSTITUCIONAL SEARCH - YEAR 2014 (AU)
(Only some records are available in English at this moment)
Artesunate is one of the semi-synthetic derivatives of artemisinin - active ingredient isolated from Artemisia annua L., a famous antimalarial. Recent studies show that this compound has anti-inflammatory, antileishmanial, immunomodulatory and antitumor effects. Our group showed that the treatment of transgenic mice presenting the fusion of the NUP98-HOXD13 genes, which develop Acute Myel…
Bone marrow neoplasias are aggressive disorders with low healing potential. As the incidence of cancer increases with age, a growing number of older individuals are receiving therapy for cancer and frequently in intensive modalities. As these older patients tend to present comorbidities, treatment decisions can often become difficult due to their fragile physical state which may affect th…
Hematological neoplasms correspond to diseases that imply abnormal and disordered proliferation of immature blood and bone marrow cells, including Myelodysplastic Syndromes (SMD), Acute Myeloid Leukemia (AML), Acute Lymphoid Leukemia (ALL), Lymphoma and Multiple Myeloma (MM), prevalent in people over the age of 65 years. Bone marrow transplantation is considered the only curative treatmen…
(Only some records are available in English at this moment)
Bone marrow neoplasias are aggressive disorders with low healing potential. As the incidence of Cancer increases with age, a growing number of older individuals are receiving therapy for Cancer and frequently in intensive modalities. As these older patients tend to present comorbidities, treatment decisions can often become difficult due to their fragile physical state which may affect th…
Bone marrow neoplasias are aggressive disorders with low healing potential. Asthe incidence of cancer increases with age, a growing number of older individualsare receiving therapy for cancer and frequently in intensive modalities. As theseolder patients tend to present comorbidities, treatment decisions can often becomedifficult due to their fragile physical state which may affect therap…
Somatic mutations in genes responsible for epigenetic modulation appear to occur years before the diagnosis of acute myeloid leukemia (AML). Bearing in mind that individuals with idiopathic neutropenias can develop AML, the present study aims to verify whether asymptomatic individuals with idiopathic cytopenias have clonal hematopoiesis. For this study, patients with idiopathic neutropeni…
(Only some records are available in English at this moment)
Acute Myeloid Leukemia (AML) corresponds to a hematological neoplasm that includes the abnormal and disordered proliferation of immature blood and bone marrow (BM) cells quite common in people over 65 years of age. BM transplantation is considered the only curative treatment for AML; however, it is not applicable to most patients due to age and the presence of comorbidities. In addition, …
2 / 2 | Ongoing research grants |
31 / 18 | Completed research grants |
5 / 5 | Ongoing scholarships in Brazil |
92 / 39 | Completed scholarships in Brazil |
2 / 1 | Completed scholarships abroad |
133 / 66 | All research grants and scholarships |
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