graduate at Educação Física from FACULDADE DE EDUCAÇÃO FÍSICA - MACKENZIE (2004) and master's at Biologia Celular e Tecidual from Instituto de Ciências Biomédicas da Universidade de São Paulo (2008). Has experience in Fitness, focusing on Fitness, acting on the following subjects: treinamento aeróbio, treinamento aeróbio, ciclo estral, consumo energét, competencia profissional, cla and fígado. (Source: Lattes Curriculum)
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Monocytes are blood cells of the immune system, when infiltrating tissues are distinguished in macrophages M1 or M2, linked to a pro or anti-inflammatory activity, respectively. The M1 phenotype is predominant in white adipose tissue (TAB) of obese subjects, it participates directly in the release of proinflammatory cytokines during the process of chronic inflammation of low grade and exh…
The brain-derived neurotrophic factor (BDNF) is known to be related to neuroprotection and neurogenesis, as well as being involved in cognition, mood, cardiovascular function and energy metabolism. BDNF plays "cross-talk" between the nervous system and immune system, which BDNF signaling pathway in lymphocytes could reflect at least in part, the same signal in the cortex, and this relatio…
The purpose of this study was to compare the effects of two similar high-intensity intermittent exercises (HIIE) but different volume 1.25km (HIIE1.25) and 2.5km (HIIE2.5) and therefore different effects on inflammatory and BDNF responses. Ten physically active male subjects (age 25.22±1.74years, body mass 78.98±7.31kg, height 1.78±0.06m, VO2peak 59.94±9.38ml*kg*min-1) performed an increm…
(Only some records are available in English at this moment)
Preliminary studies indicate that physically active individuals have a better response to the SARS-CoV-2 compared to sedentary ones, although the long-term effects of virus on the inflammatory, metabolic, cardiovascular and mental health profile are lacking in better and complete knowledge. Additionally, overweight and obesity are consistently associated with more severe forms of manifest…
Sedentary behavior, physical inactivity and unhealthy nutrition are key factors which contribute to an increased level of body adiposity, especially visceral adipose tissue. Cardiorespiratory fitness level is considered a potential modifier of the inverse association between visceral obesity and mortality. Combined to these factors, low-grade inflammation promotes insulin and adiponectin …
During the period of the COVID-19 pandemic, studies have shown a high rate of sedentary behavior, physical inactivity, mood disorders, and reduced sleep quality, in parallel with a reduction in physical exercise. The importance of physical exercise for the maintenance of physical and mental health is well established in the literature, exerting positive effects in the treatment of cogniti…
Immunosenescence is the progressive dysfunction of the immune system that occurs with aging and results in greater susceptibility to infections, autoimmune diseases, and cancer. There is evidence that exercise is a safe intervention to reduce immunosenescence. The purpose of this study is to explore the effects of lifelong exercise on several markers of immunosenescence and inflammation w…
Derived from a bone marrow myeloid lineage, monocytes are blood cells of the immune system that, when infiltrated into tissues, differentiate into anti-inflammatory (M2) or pro-inflammatory (M1) macrophages. Polarization for M1 phenotype is enhanced in White Adipose Tissue (WAT) of obese and elderly subjects, exhibits potential in the production and release of inflammatory cytokines, favo…
(Only some records are available in English at this moment)
The major aim of this study is to investigate the immunometabolic mechanisms of the antitumoral effects of NK cells in individuals engaged in lifelong exercise. The question that we propose to address is this proposal is: Can regular physical exercise create a metabolic and immune environment that suppresses tumorigenesis? We hypothesized that exercise-induced delay in immunosenescence, s…
Derived from a myeloid lineage in the bone marrow, monocytes are blood cells of the immune system that in tissues differentiate into macrophages with an anti-inflammatory (M2) or pro-inflammatory (M1) state. The polarization of macrophages to the inflammatory state in metabolic disorder, or repair in tissue and systemic homeostatic situations, is well established in the literature, showin…
The level of cardiorespiratory fitness is considered a potential modifier of the inverse association between visceral obesity and mortality. Combined with this factor, low-grade inflammation promotes insulin resistance and adiponectin as well as dysregulation of the adaptive immune system such as T lymphocytes. The energy demand of T lymphocytes is regulated by nutrient sensors such as mT…
In the present study, we aim to investigate the effects of short-term exercise (2 weeks) on the acute regulation of the expression of several cytokines that possess anti-inflammatory properties including interleukin-6 (IL-6) and interleukin-10 (IL-10) and the underlying mechanism involving signal transducer and activator of transcription protein (STAT3) and toll-like receptor 4 (TLR-4). T…
Several studies have suggested brain-derived neurotrophic factor (BDNF) as a key protein in adaptive responses of the nervous and immune system, metabolic and heart rate regulation. BDNF is a member of neurotrophin family of growth factors and it is present in two isoforms: pro-BDNF, with apoptotic character, and mature BDNF related to cell survival, and then a better neuronal function, a…
(Only some records are available in English at this moment)
| 8 / 5 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 19 / 18 | Completed scholarships in Brazil |
| 2 / 2 | Ongoing scholarships abroad |
| 6 / 6 | Completed scholarships abroad |
| 37 / 33 | All research grants and scholarships |
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CV Lattes
ORCID