CV Lattes
Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Ciencias Biologicas Modalidade Medica from Universidade Federal de São Paulo (1978), master's at Biochemistry from Universidade Federal de São Paulo (1981) and doctorate at Biochemistry from Universidade Federal de São Paulo (1984). Has experience in Biochemistry, focusing on Molecular Biology, acting on the following subjects: glycosphingolipids, anticorpo monoclonal, leishmania, glycosylinositol phosphoceramides and monoclonal antibodies. (Source: Lattes Curriculum)
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Inositol phosphorylceramide (IPC), the major sphingolipid in the genus Leishmania but not found in mammals, is considered a potentially useful target for chemotherapy against leishmaniasis. Leishmania (Viannia) braziliensis is endemic in Latin America and causes American tegumentary leishmaniasis. We demonstrated that IPCs are localized internally in parasites, using a specific monoclonal…
This project aims, in one hand, to consolidate the FAP-Unifesp Publishing House as a link between the multiple campi of Unifesp in terms of intellectual production. In the other hand, this project aims to improve infrastructure of the Foundation to give a belter support to activities related to teaching and research. Regarding the publishing house, this is a funding project for the follow…
Paracoccidioidomycosis (PCM) is a granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis. The immunoglobulin classes and isotypes of antibodies directed to acidic glycosphingolipids (GSLs) and glucosylceramide of P. brasiliensis were determined by ELISA for sera from 31 PCM patients. The reactivity of 38 serum sample was analyzed considering the stage of treatm…
(Only some records are available in English at this moment)
Recent data show that inositol phosphorylceramide (IPC), sterols and glycoinositolphospholipids are preferentially distributed in detergent-resistant membranes microdomains (DRMs) of Leishmania (Viannia) braziliensis promastigotes. Although is well known that membrane microdomains from mammalian cells are involved in process such as adhesion, signal transduction, protein polarized traffic…
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| 10 / 1 | Completed scholarships in Brazil |
| 26 / 11 | All research grants and scholarships |
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