graduation at Ciencias Biologicas from Universidade Federal do Rio de Janeiro (1997), master's at Byophysics from Universidade Federal do Rio de Janeiro (2000) and doctorate at Biochemistry from Universidade de São Paulo (2004). Has experience in Genetics, focusing on Molecular Genetics and of Microorganisms, acting on the following subjects: regulação da expressão gênica, sistemas de secrecao, desenvolvimento embrionário, estresse extracitoplasmático and bmp-4. (Source: Lattes Curriculum)
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Bacterial secretion systems are transenvelope protein complexes that promote the translocation of effector proteins directly into target cells or the extracellular milieu, and thus play fundamental roles in environmental adaptation. Type VI secretion systems (T6SS) are widespread in Proteobacteria and target prokaryotic and/or eukaryotic cells, acting as antibacterial weapons or anti-host…
Bacterial type VI secretion systems (T6SS) are multiprotein complexes that translocate protein effectors and/or toxins to target cells, playing major roles in interspecies competition, virulence and environmental adaptation in several bacteria. Xanthomonas citri subsp. citri is the causative agent of citrus canker disease, infecting all citrus crops. Previous studies by our research group…
Bacterial type VI secretion systems (T6SS) are protein complexes that span the bacterial cell envelope and are involved in protein translocation to target cells. It was not until recently that T6SS were first described and structural and functional studies indicate that they act by a mechanism similar to injection of DNA into bacterial cells by bacteriophages, specially the T4 phage. T6SS…
Bacteria are ubiquitous organisms that have a vast repertoire of strategies to survive and respond to environmentalchanges. The Proteobacteria Xanthomonas citri subsp. citri is the causative agent of citrus canker, a disease that resultsfrom colonization of Citrus plant tissue and affects all economically important cultivars. Secretion Systems are proteincomplexes that cross the bacterial…
Citriculture, an important economic activity in Brazil, is threatened by diseases that attack crops, such as citrus canker produced by Xanthomonas citri, which leads to reduced productivity and significant economic losses. Bacterial sigma factors are dissociable subunits of RNA polymerases that are responsible for the recognition of promoters and for promoting the initiation of transcript…
Bacterial Secretion Systems are multiprotein nanomachines that translocate proteins to the extracellular millieu or directly into target cells, playing essential roles in several aspects of bacterial physiology, including virulence and interbacterial competition. Recently, our research group described the role of Xanthomonas citri pv citri type 6 secretion system (T6SS) in resistance to p…
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Type 6 Secretion Systems (T6SS) are bacterial nanomachines that deliver effector proteins or toxins directly into prokaryotic and/or eukaryotic target cells. These devices are involved in the interspecific competition and virulence playing fundamental roles in bacterial fitness in their ecological niches. The T6SS of Xanthomonas citri pv citri is required for resistance against the bacter…
| 1 / 1 | Ongoing research grants |
| 4 / 2 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 9 / 7 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 16 / 12 | All research grants and scholarships |
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CV Lattes
ORCID