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Elza Tiemi Sakamoto Hojo

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Universidade de São Paulo (USP). Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto (FFCLRP)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

bachelor's at Licenciatura Em Ciências Biológicas from Faculdade de Filosofia Ciências e Letras de Ribeirão Preto (1976), master's at Pós Graduação em Genética from Faculdade de Medicina de Ribeirão Preto - USP (1980) and doctorate at Pós graduação em Genética from Faculdade de Medicina de Ribeirão Preto - USP (1986). She is currently associate professor at Universidade de São Paulo. Has experience in Genetics, focusing on Mutagenesis, acting on the following subjects: apoptosis, ionizing radiation, gene expression profiles studied by DNA microarrays. (Source: Lattes Curriculum)

Research grants
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Scholarships abroad
FAPESP support in numbers * Updated April 10, 2021
Total / Available in English
Most frequent collaborators in research granted by FAPESP
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Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (25)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications22
Citations280
Cit./Article12.7
Data from Web of Science

GODOY, PAULO R. D. V.; MONTALDI, ANA PAULA L.; SAKAMOTO-HOJO, ELZA T.. HEB silencing induces anti-proliferative effects on U87MG cells cultured as neurospheres and monolayers. MOLECULAR MEDICINE REPORTS, v. 14, n. 6, A, p. 5253-5260, . Web of Science Citations: 1. (09/10925-6)

LEANDRO, GIOVANA SILVA; EVANGELISTA, ADRIANE FEIJO; LOBO, ROMULO REBOUCAS; XAVIER, DANILO JORDAO; MORIGUTI, JULIO CESAR; SAKAMOTO-HOJO, ELZA TIEMI. Changes in Expression Profiles Revealed by Transcriptomic Analysis in Peripheral Blood Mononuclear Cells of Alzheimer's Disease Patients. JOURNAL OF ALZHEIMER'S DISEASE, v. 66, n. 4, p. 1483-1495, . Web of Science Citations: 0. (12/07879-5, 13/09352-7)

BRASSESCO, MARIA SOL; MONTALDI, ANA PAULA; GRAS, DIANA ESTER; DE PAULA QUEIROZ, ROSANE GOMES; MARTINEZ-ROSSI, NILCE MARIA; TONE, LUIZ GONZAGA; SAKAMOTO-HOJO, ELZA TIEMI. MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals. GENETICS AND MOLECULAR BIOLOGY, v. 32, n. 2, p. 234-241, . Web of Science Citations: 6.

EVANGELISTA, ADRIANE F.; COLLARES, CRISTHIANNA V. A.; XAVIER, DANILO J.; MACEDO, CLAUDIA; MANOEL-CAETANO, FERNANDA S.; RASSI, DIANE M.; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; SAKAMOTO-HOJO, ELZA T.; NGUYEN, CATHERINE; et al. Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation. BMC MEDICAL GENOMICS, v. 7, . Web of Science Citations: 16. (10/12069-7, 08/56594-8)

COLLARES, C. V. A.; EVANGELISTA, A. F.; XAVIER, D. J.; TAKAHASHI, P.; ALMEIDA, R.; MACEDO, C.; MANOEL-CAETANO, F.; FOSS, M. C.; FOSS-FREITAS, M. C.; RASSI, D. M.; et al. Transcriptome meta-analysis of peripheral lymphomononuclear cells indicates that gestational diabetes is closer to type 1 diabetes than to type 2 diabetes mellitus. MOLECULAR BIOLOGY REPORTS, v. 40, n. 9, p. 5351-5358, . Web of Science Citations: 10. (10/12069-7, 08/56594-8)

DOS SANTOS MOREIRA, NATALIA CHERMONT; BARBOSA DE FREITAS LIMA, JESSICA ELLEN; CANTUARIA CHIERRITO, TALITA PEREZ; CARVALHO, IVONE; SAKAMOTO-HOJO, ELZA TIEMI. Novel Hybrid Acetylcholinesterase Inhibitors Induce Differentiation and Neuritogenesis in Neuronal Cells in vitro Through Activation of the AKT Pathway. JOURNAL OF ALZHEIMER'S DISEASE, v. 78, n. 1, p. 353-370, . Web of Science Citations: 0. (18/21709-1, 17/15123-1)

XAVIER, DANILO J.; TAKAHASHI, PAULA; MANOEL-CAETANO, FERNANDA S.; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; DONADI, EDUARDO A.; PASSOS, GERALDO A.; SAKAMOTO-HOJO, ELZA T.. One-week intervention period led to improvements in glycemic control and reduction in DNA damage levels in patients with type 2 diabetes mellitus. Diabetes Research and Clinical Practice, v. 105, n. 3, p. 356-363, . Web of Science Citations: 6. (10/12069-7, 08/56594-8)

BRASSESCO, MARIA SOL; XAVIER, DANILO JORDAO; CAMPAROTO, MARJORI LEIVA; MONTALDI, ANA PAULA; D'AURIA VIEIRA DE GODOY, PAULO ROBERTO; SCRIDELI, CARLOS ALBERTO; TONE, LUIZ GONZAGA; SAKAMOTO-HOJO, ELZA TIEMI. Cytogenetic Instability in Childhood Acute Lymphoblastic Leukemia Survivors. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, . Web of Science Citations: 5.

SAKAMOTO-HOJO, E. T.; PEREIRA, E.; FACHIN, A. L.; CARDOSO, R. S.; DONADI, E. A.; PASSOS, G. A. S.; MELLO, S. S.; JUNTA, C. M.. Gene expression profiles in human cells submitted to genotoxic stress. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, v. 544, n. 2-3, p. 403-413, . (99/12135-9)

PEITL‚ P.; MELLO‚ S.S.; CAMPAROTO‚ M.L.; PASSOS‚ G.A.S.; HANDE‚ M.P.; CARDOSO‚ R.S.; SAKAMOTO-HOJO‚ E.T.. Chromosomal rearrangements involving telomeric DNA sequences in Balb/3T3 cells transfected with the Ha-ras oncogene. MUTAGENESIS, v. 17, n. 1, p. 67-72, .

MANOEL-CAETANO, FERNANDA S.; XAVIER, DANILO J.; EVANGELISTA, ADRIANE F.; TAKAHASHI, PAULA; COLLARES, CRISTHIANNA V.; PUTHIER, DENIS; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; DONADI, EDUARDO A.; PASSOS, GERALDO A.; et al. Gene expression profiles displayed by peripheral blood mononuclear cells from patients with type 2 diabetes mellitus focusing on biological processes implicated on the pathogenesis of the disease. Gene, v. 511, n. 2, p. 151-160, . Web of Science Citations: 26. (10/12069-7, 08/56594-8)

BRASSESCO, MARIA S.; MONTALDI, ANA P.; GRAS, DIANA E.; CAMPAROTO, MARJORI L.; MARTINEZ-ROSSI, NILCE M.; SCRIDELI, CARLOS A.; TONE, LUIZ G.; SAKAMOTO-HOJO, ELZA T.. Cytogenetic and molecular analysis of MLL rearrangements in acute lymphoblastic leukaemia survivors. MUTAGENESIS, v. 24, n. 2, p. 153-160, . Web of Science Citations: 9.

BASSI, C. L.; MELLO, S. S.; CARDOSO, R. S.; GODOY, P. D. V.; FACHIN, A. L.; JUNTA, C. M.; SANDRIN-GARCIA, P.; CARLOTTI, C. G.; FALCAO, R. P.; DONADI, E. A.; et al. Transcriptional changes in U343 MG-a glioblastoma cell line exposed to ionizing radiation. HUMAN & EXPERIMENTAL TOXICOLOGY, v. 27, n. 12, p. 919-929, . Web of Science Citations: 14. (99/12135-9)

FACHIN, ANA LUCIA; MELLO, STEPHANO SPANO; SANDRIN-GARCIA, PAULA; JUNTA, CRISTINA MORAES; GHILARDI-NETTO, THOMAZ; DONADI, EDUARDO ANTONIO; DA SILVA PASSOS, GERALDO ALEIXO; SAKAMOTO-HOJO, ELZA TIEMI. Gene Expression Profiles in Radiation Workers Occupationally Exposed to Ionizing Radiation. JOURNAL OF RADIATION RESEARCH, v. 50, n. 1, p. 61-71, . Web of Science Citations: 43. (99/12135-9)

MELLO, STEPHANO S.; FACHIN, ANA L.; JUNTA, CRISTINA M.; SANDRIN-GARCIA, PAULA; DONADI, EDUARDO A.; PASSOS, GERALDO A. S.; SAKAMOTO-HOJO, ELZA T.. Delayed Effects of Exposure to a Moderate Radiation Dose on Transcription Profiles in Human Primary Fibroblasts. Environmental and Molecular Mutagenesis, v. 52, n. 2, p. 117-129, . Web of Science Citations: 8. (99/12135-9)

FACHIN‚ A.L.; MELLO‚ S.S.; SANDRIN-GARCIA‚ P.; JUNTA‚ C.M.; DONADI‚ E.A.; PASSOS‚ G.A.S.; SAKAMOTO-HOJO‚ E.T.. Gene expression profiles in human lymphocytes irradiated in vitro with low doses of gamma rays. RADIATION RESEARCH, v. 168, n. 6, p. 650-665, . (99/12135-9)

XAVIER, DANILO J.; TAKAHASHI, PAULA; EVANGELISTA, ADRIANE F.; FOSS-FREITAS, MARIA C.; FOSS, MILTON C.; DONADI, EDUARDO A.; PASSOS, GERALDO A.; SAKAMOTO-HOJO, ELZA T.. Assessment of DNA damage and mRNA/miRNA transcriptional expression profiles in hyperglycemic versus non-hyperglycemic patients with type 2 diabetes mellitus. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, v. 776, n. SI, p. 98-110, . Web of Science Citations: 11. (10/12069-7, 08/56594-8)

SYKORA, P.; KANNO, S.; AKBARI, M.; KULIKOWICZ, T.; BAPTISTE, B. A.; LEANDRO, G. S.; LU, H.; TIAN, J.; MAY, A.; BECKER, K. A.; et al. DNA Polymerase Beta Participates in Mitochondrial DNA Repair. MOLECULAR AND CELLULAR BIOLOGY, v. 37, n. 16, . Web of Science Citations: 20. (13/11052-1)

MONTALDI, ANA P.; LIMA, SARAH C. G.; GODOY, PAULO R. D. V.; XAVIER, DANILO J.; SAKAMOTO-HOJO, ELZA T.. PARP-1 inhibition sensitizes temozolomide-treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity andPTENproficiency. ONCOLOGY REPORTS, v. 44, n. 5, p. 2275-2287, . Web of Science Citations: 0. (16/17862-3, 13/12033-0, 13/09352-7)

GODOY, PAULO R. D. V.; POUR KHAVARI, ALI; RIZZO, MARZIA; SAKAMOTO-HOJO, ELZA T.; HAGHDOOST, SIAMAK. Targeting NRF2, Regulator of Antioxidant System, to Sensitize Glioblastoma Neurosphere Cells to Radiation-Induced Oxidative Stress. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, v. 2020, . Web of Science Citations: 0. (16/16163-4)

FACHIN‚ A.L.; MELLO‚ S.S.; SANDRIN-GARCIA‚ P.; JUNTA‚ C.M.; DONADI‚ E.A.; PASSOS‚ G.A.S.; SAKAMOTO-HOJO‚ E.T.. Gene expression profiles in human lymphocytes irradiated in vitro with low doses of gamma rays. RADIATION RESEARCH, v. 168, n. 6, p. 650-665, . (99/12135-9)

MELLO, STEPHANO S.; FACHIN, ANA L.; JUNTA, CRISTINA M.; SANDRIN-GARCIA, PAULA; DONADI, EDUARDO A.; PASSOS, GERALDO A. S.; SAKAMOTO-HOJO, ELZA T.. Delayed Effects of Exposure to a Moderate Radiation Dose on Transcription Profiles in Human Primary Fibroblasts. Environmental and Molecular Mutagenesis, v. 52, n. 2, p. 117-129, . Web of Science Citations: 8. (99/12135-9)

BASSI, C. L.; MELLO, S. S.; CARDOSO, R. S.; GODOY, P. D. V.; FACHIN, A. L.; JUNTA, C. M.; SANDRIN-GARCIA, P.; CARLOTTI, C. G.; FALCAO, R. P.; DONADI, E. A.; et al. Transcriptional changes in U343 MG-a glioblastoma cell line exposed to ionizing radiation. HUMAN & EXPERIMENTAL TOXICOLOGY, v. 27, n. 12, p. 919-929, . Web of Science Citations: 14. (99/12135-9)

MONTALDI, ANA P.; LIMA, SARAH C. G.; GODOY, PAULO R. D. V.; XAVIER, DANILO J.; SAKAMOTO-HOJO, ELZA T.. PARP-1 inhibition sensitizes temozolomide-treated glioblastoma cell lines and decreases drug resistance independent of MGMT activity andPTENproficiency. ONCOLOGY REPORTS, v. 44, n. 5, p. 2275-2287, . Web of Science Citations: 0. (16/17862-3, 13/12033-0, 13/09352-7)

GODOY, PAULO R. D. V.; POUR KHAVARI, ALI; RIZZO, MARZIA; SAKAMOTO-HOJO, ELZA T.; HAGHDOOST, SIAMAK. Targeting NRF2, Regulator of Antioxidant System, to Sensitize Glioblastoma Neurosphere Cells to Radiation-Induced Oxidative Stress. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, v. 2020, . Web of Science Citations: 0. (16/16163-4)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

MELLO, Stephano Spanó. Análise da expressão de genes reguladores do ciclo celular induzida pela radiação ionizante em fibroblastos humanos.  viii, 63 f. Dissertação (Mestrado) -  Faculdade de Medicina de Ribeirão Preto.  Universidade de São Paulo (USP).  Ribeirão Preto.  (00/01005-6

BERARDINELLI, Gustavo Nóriz. Análise de Marcadores Gênicos de Estresse Genotóxico em Fibroblastos Humanos Normais e Células de Glioblastoma.. Dissertação (Mestrado) -  Faculdade de Medicina de Ribeirão Preto.  Universidade de São Paulo (USP).  Ribeirão Preto.  (09/03991-2

LEANDRO, Giovana da Silva. Alterações na expressão gênica de células mononucleares do sangue periférico de pacientes com a doença de Alzheimer e consequências da deficiência de polimerase β em fibroblastos de camundongos. Tese (Doutorado) -  Faculdade de Medicina de Ribeirão Preto.  Universidade de São Paulo (USP).  Ribeirão Preto.  (12/07879-5

TAKAHASHI, Paula. Perfis de Expressão Gênica e Possíveis Interações entre microRNAs e mRNAs em Diabetes Mellitus Tipo 1 com Enfoque em Resposta ao Estresse Oxidativo e Reparo do DNA. Tese (Doutorado) -  Faculdade de Medicina de Ribeirão Preto.  Universidade de São Paulo (USP).  Ribeirão Preto.  (10/12069-7

MONTALDI, Ana Paula de Lima. Influência do Gene APE1/REF-1 nas Respostas Celulares das Linhagens de Glioblastoma ao Quimioterápico Temozolomida. Tese (Doutorado) -  Faculdade de Medicina de Ribeirão Preto.  Universidade de São Paulo (USP).  Ribeirão Preto.  (09/10106-5

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