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Elizabeth Igne Ferreira

CV Lattes ResearcherID


Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

bachelor's at Farmácia e Bioquímica from Universidade de São Paulo (1972), master's at Pharmacy from Universidade de São Paulo (1979) and doctorate at Chemistry from Universidade de São Paulo (1987). Has experience in Pharmacy, Medicinal Chemistry, working on Drug Design of candidates for malaria, Chagas disease, leishmaniasis and tuberculosis. (Source: Lattes Curriculum)

Research grants
Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated October 12, 2019
Total / Available in English
Most frequent collaborators in research granted by FAPESP
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Use this Research Supported by FAPESP (BV/FAPESP) channel only to send messages referring to FAPESP-funded scientific projects.


 

 

 

 

Keywords used by the researcher
Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (40)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications26
Citations193
Cit./Article7.4
Data from Web of Science

BRITO, CHARLES DE LIMA; GOULART TROSSINI, GUSTAVO HENRIQUE; FERREIRA, ELIZABETH IGNE; LA-SCALEA, MAURO AQUILES. Nitrofurazone and its Nitroheterocyclic Analogues: a Study of the Electrochemical Behavior in Aqueous Medium. Journal of the Brazilian Chemical Society, v. 24, n. 12, p. 1964+, . Web of Science Citations: 5. (11/11499-0)

RANDO, DANIELA GONCALVES; GIAROLLA, JEANINE; MESQUITA PASQUALOTO, KERLY FERNANDA; FERREIRA, ELIZABETH IGNE. Chalcones and N-acylhydrazones: direct analogues? Exploratory data analysis applied to potential novel antileishmanial agents. Brazilian Journal of Pharmaceutical Sciences, v. 46, n. 2, p. 311-321, . Web of Science Citations: 3. (01/01192-3)

PAULA, FAVERO R.; TROSSINI, GUSTAVO H. G.; FERREIRA, ELIZABETH I.; SERRANO, SILVIA H. P.; MENEZES, CARLA M. S.; TAVARES, LEOBERTO C.. Theoretical and Voltammetric Studies of 5-Nitro-heterocyclic Derivatives with Potential Trypanocidal Activities. Journal of the Brazilian Chemical Society, v. 21, n. 4, p. 740-749, . Web of Science Citations: 5. (01/01192-3)

GOULART TROSSINI, GUSTAVO HENRIQUE; CHIN, CHUNG MAN; DE SOUZA MENEZES, CARLA MARIA; FERREIRA, ELIZABETH IGNE. Molecular Modeling Suggests Cruzain Specificity for Peptide Primaquine Prodrugs. LETTERS IN DRUG DESIGN & DISCOVERY, v. 7, n. 7, p. 528-533, . Web of Science Citations: 4. (01/01192-3)

QUINCOCES SUAREZ, JOSE AGUSTIN; RANDO, DANIELA GONCALES; SANTOS, REGINALDO PEREIRA; GONCALVES, CAROLINA PASSARELLI; FERREIRA, ELIZABETH; DE CARVALHO, JOAO ERNESTO; KOHN, LUCIANA; MARIA, DURVANEI AUGUSTO; FAIAO-FLORES, FERNANDA; MICHALIK, DIRK; et al. New antitumoral agents I: In vitro anticancer activity and in vivo acute toxicity of synthetic 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one and derivatives. Bioorganic & Medicinal Chemistry, v. 18, n. 17, p. 6275-6281, . Web of Science Citations: 16.

LA-SCALEA, M. A.; TROSSINI, G. H. G.; MENEZES, C. M. S.; CHUNG, M. C.; FERREIRA, E. I.. Electrochemical Reduction Using Glassy Carbon Electrode in Aqueous Medium of a Potential Anti-Chagas Drug: NFOH. Journal of the Electrochemical Society, v. 156, n. 7, p. F93-F97, . Web of Science Citations: 9. (01/01192-3)

CHUNG, MAN-CHIN; GUIDO, RAFAEL VICTÓRIO CARVALHO; MARTINELLI, TATIANE FAVARATO; GONÇALVES, MARINEI FERREIRA; POLLI, MICHELLE CARNEIRO; BOTELHO, KATIA CIRLENE ALVES; VARANDA, ELIANA APARECIDA; COLLI, WALTER; MIRANDA, M. TERÊSA M.; FERREIRA, ELIZABETH IGNE. Synthesis and in vitro evaluation of potential antichagasic hydroxymethyinitrofurazone (NFOH-121): A new nitrofurazone prodrug. Bioorganic & Medicinal Chemistry, v. 11, n. 22, p. 4779-4783, . (95/04562-3, 01/01192-3)

TROSSINI, GUSTAVO H. G.; GIAROLLA, JEANINE; DE REZENDE, LEANDRO; DO AMARAL, ANTONIA T.; ZAIM, MARCIO H.; BRUNS, ROY E.; FERREIRA, ELIZABETH I.. Synthesis Optimization of Hydroxymethylnitrofurazone, an Antichagasic Candidate, Using 3(2) Factorial Design. Letters in Organic Chemistry, v. 7, n. 3, p. 191-195, . Web of Science Citations: 6. (01/01192-3)

GIAROLLA, JEANINE; FERREIRA, ELIZABETH IGNE. Drug Design for Neglected Disease in Brazil. MINI-REVIEWS IN MEDICINAL CHEMISTRY, v. 15, n. 3, p. 220-242, . Web of Science Citations: 5. (12/50034-6)

SANTOS, SORAYA DA SILVA; GIAROLLA, JEANINE; PASQUALOTO, KERLY F. M.; FERREIRA, ELIZABETH I.. Molecular modelling as a tool for studying the disassembly of potentially leishmanicide-targeted dendrimer. MOLECULAR SIMULATION, v. 39, n. 11, p. 860-867, . Web of Science Citations: 3. (01/01192-3)

DANIELA GONÇALES RANDO; CARLOS ALBERTO BRANDT; ELIZABETH IGNE FERREIRA. Use of N-methylene phosphonic chitosan to obtain an isoniazid prodrug. Revista Brasileira de Ciências Farmacêuticas, v. 40, n. 3, p. 334-344, .

LORENA BLAU; RENATO FARINA MENEGON; MAN CHIN CHUNG. Pró-fármaco ativado por enzima, uma estratégia promissora na quimioterapia. Química Nova, v. 29, n. 6, p. 1307-1317, . (01/01192-3)

GIAROLLA, JEANINE; RANDO, DANIELA G.; PASQUALOTO, KERLY F. M.; ZAIM, MARCIO H.; FERREIRA, ELIZABETH I.. Molecular modeling as a promising tool to study dendrimer prodrugs delivery. JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, v. 939, n. 1-3, p. 133-138, . Web of Science Citations: 10. (01/01192-3)

LA-SCALEA, MAURO AQUILES; MENEZES, CARLA MARIA DE SOUZA; JULIÃO, MURILO SÉRGIO DA SILVA; CHUNG, MAN CHIN; SERRANO, SÍLVIA HELENA PIRES; FERREIRA, ELIZABETH IGNE. Voltammetric behavior of nitrofurazone and its hydroxymethyl prodrug with potential anti-Chagas activity. Journal of the Brazilian Chemical Society, v. 16, n. 4, p. 774-782, . (01/01192-3)

GUIDO, RAFAEL V. C.; TROSSINI, GUSTAVO H. G.; CASTILHO, MARCELO S.; OLIVA, GLAUCIUS; FERREIRA, ELIZABETH I.; ANDRICOPULO, ADRIANO D.. Structure-activity relationships for a class of selective inhibitors of the major cysteine protease from Trypanosoma cruzi. Journal of Enzyme Inhibition and Medicinal Chemistry, v. 23, n. 6, p. 964-973, . Web of Science Citations: 26. (01/01192-3)

BARBOSA, C. F.; OKUDA, E. S.; CHUNG, M. C.; FERREIRA, E. I.; CICARELLI, R. M. B.. Rapid test for the evaluation of the activity of the prodrug hydroxymethylnitrofurazone in the processing of Trypanosoma cruzi messenger RNAs. Brazilian Journal of Medical and Biological Research, v. 40, n. 1, p. 33-39, . (01/01192-3)

JULIÃO, MURILO S. DA S.; FERREIRA, ELIZABETH I.; FERREIRA, NEIDENÊI G.; SERRANO, SILVIA H. P.. Voltammetric detection of the interactions between RNO2 circle- and electron acceptors in aqueous medium at highly boron doped diamond electrode (HBDDE). Electrochimica Acta, v. 51, n. 24, p. 5080-5086, . (01/01192-3)

LA-SCALEA, MAURO A.; MENEZES, CARLA M. S.; MATSUTAMI, GUILHERME C.; POLLI, MICHELLE C.; SERRANO, SÍLVIA H. P.; FERREIRA, ELIZABETH I.. Molecular modeling of the voltammetric oxidation at a glassy carbon electrode of the antimalarial drug primaquine and its prodrugs succinylprimaquine and maleylprimaquine. Electrochimica Acta, v. 51, n. 24, p. 5103-5111, . (01/01192-3)

JULIÃO, MURILO SÉRGIO DA SILVA; ALMEIDA, ÉRICA CRISTINA; LA SCALEA, MAURO AQUILES; FERREIRA, NEIDENÊI GOMES; COMPTON, RICHARD G.; SERRANO, SÍLVIA HELENA PIRES. Voltammetric behavior of nitrofurazone at highly boron doped diamond electrode. Electroanalysis, v. 17, n. 3, p. 269-274, . (01/01192-3)

GIAROLLA, JEANINE; MESQUITA PASQUALOTO, KERLY FERNANDA; FERREIRA, ELIZABETH I.. Design and exploratory data analysis of a second generation of dendrimer prodrugs potentially antichagasic and leishmanicide. MOLECULAR DIVERSITY, v. 17, n. 4, p. 711-720, . Web of Science Citations: 8. (12/50034-6)

GIAROLLA, JEANINE; PASQUALOTO, KERLY F. M.; RANDO, DANIELA G.; ZAIM, MARCIO H.; FERREIRA, ELIZABETH I.. Molecular modeling study on the disassembly of dendrimers designed as potential antichagasic and antileishmanial prodrugs. Journal of Molecular Modeling, v. 18, n. 5, p. 2257-2269, . Web of Science Citations: 8. (01/01192-3)

RANDO‚ D.G.; SATO‚ D.N.; SIQUEIRA‚ L.; MALVEZZI‚ A.; LEITE‚ C.Q.F.; DO_AMARAL‚ A.T.; FERREIRA‚ E.I.; TAVARES‚ L.C.. Potential tuberculostatic agents. Topliss application on benzoic acid [(5-nitro-thiophen-2-yl)-methylene]-hydrazide series. Bioorganic & Medicinal Chemistry, v. 10, n. 3, p. 557-560, .

ISHIKI, HAMILTON MITSUGU; DO AMARAL, ANTONIA T.. Three-Dimensional Quantitative Structure-Activity Relationship Study of Antitumor 2-Formylpyridine Thiosemicarbazones Derivatives as Inhibitors of Ribonucleotide Reductase. QSAR & COMBINATORIAL SCIENCE, v. 28, n. 11-12, p. 1334-1345, . Web of Science Citations: 3. (01/01192-3)

FERREIRA, ELIZABETH IGNE; MALVEZZI, ALBERTO; REZENDE, LEANDRO DE; IZIDORO, MARIO AUGUSTO; CEZARI, MARIA HELENA SEDENHO; JULIANO, LUIZ; AMARAL, ANTONIA T. -DO. Uncovering false positives on a virtual screening search for cruzain inhibitors. Bioorganic & Medicinal Chemistry Letters, v. 18, n. 1, p. 350-354, . (01/01192-3)

BRACCO‚ ME; CHIAPPARINI‚ M.; LOZEA‚ A.; NAVARRA‚ FS; NIELSEN‚ M.. D and [rho] mesons: who resolves whom?. Physics Letters B, v. 521, n. 1-2, p. 1-6, . (01/01192-3)

DA SILVA‚ R.P.; LIMA‚ A.W.O.; SERRANO‚ S.H.P.. Simultaneous voltammetric detection of ascorbic acid‚ dopamine and uric acid using a pyrolytic graphite electrode modified into dopamine solution. Analytica Chimica Acta, v. 612, n. 1, p. 89-98, . (01/01192-3)

BUENO, RENATA V.; BRAGA, RODOLPHO C.; SEGRETTI, NATANAEL D.; FERREIRA, ELIZABETH I.; TROSSINI, GUSTAVO H. G.; ANDRADE, CAROLINA H.. New Tuberculostatic Agents Targeting Nucleic Acid Biosynthesis: Drug Design using QSAR Approaches. CURRENT PHARMACEUTICAL DESIGN, v. 20, n. 27, p. 4474-4485, . Web of Science Citations: 14. (11/11499-0)

DE ARAUJO, RENAN VINICIUS; SANTOS, SORAYA DA SILVA; FERREIRA, ELIZABETH IGNE; GIAROLLA, JEANINE. New Advances in General Biomedical Applications of PAMAM Dendrimers. Molecules, v. 23, n. 11, . Web of Science Citations: 3. (15/19438-1, 17/21154-7)

MALVEZZI‚ A.; DE REZENDE‚ L.; AMARAL‚ A.T.; OTHERS. Pharmacophore Model of Cruzain Inhibitors. QSAR & COMBINATORIAL SCIENCE, v. 28, n. 8, p. 781-784, . (01/01192-3)

PASSOS JR‚ G.A.S.; QUEIROZ‚ R.G.P.; BR{\=U}LÉ‚ A.. EcoRI restriction fragment-length polymorphism of the human immunoglobulin variable lambda 8 (IGLV8) subgroup reveals a gene family. HUMAN IMMUNOLOGY, v. 55, n. 2, p. 96-102, .

TROSSINI, GUSTAVO H. G.; MALVEZZI, ALBERTO; T-DO AMARAL, ANTONIA; RANGEL-YAGUI, CARLOTA OLIVEIRA; IZIDORO, MARIO A.; CEZARI, MARIA HELENA S.; JULIANO, LUIZ; CHIN, CHUNG MAN; MENEZES, CARLA M. S.; FERREIRA, ELIZABETH IGNE. Cruzain inhibition by hydroxymethylnitrofurazone and nitrofurazone: investigation of a new target in Trypanosoma cruzi. Journal of Enzyme Inhibition and Medicinal Chemistry, v. 25, n. 1, p. 62-67, . Web of Science Citations: 23. (01/01192-3)

PRIMI, MARINA CANDIDO; MALTAROLLO, VINICIUS GONCALVES; MAGALHAES, JULIANA GALLOTTINI; DE SA, MATHEUS MALTA; RANGEL-YAGUI, CARLOTA OLIVEIRA; GOULART TROSSINI, GUSTAVO HENRIQUE. Convergent QSAR studies on a series of NK3 receptor antagonists for schizophrenia treatment. Journal of Enzyme Inhibition and Medicinal Chemistry, v. 31, n. 2, p. 283-294, . Web of Science Citations: 2. (13/15947-3)

SANTOS, SORAYA DA SILVA; GIAROLLA, JEANINE; PASQUALOTO, KERLY F. M.; FERREIRA, ELIZABETH I.. In silico study to analyse the disassembly of quercetin-targeted dendrimers potentially leishmanicide. MOLECULAR SIMULATION, v. 41, n. 18, p. 1495-1508, . Web of Science Citations: 1. (12/50034-6)

SANTOS, SORAYA DA SILVA; FERREIRA, ELIZABETH IGNE; GIAROLLA, JEANINE. Dendrimer Prodrugs. Molecules, v. 21, n. 6, . Web of Science Citations: 6. (15/19438-1, 12/19031-0)

SILVA, FREDSON T.; FRANCO, CAIO H.; FAVARO, DENIZE C.; FREITAS-JUNIOR, LUCIO H.; MORAES, CAROLINA B.; FERREIRA, ELIZABETH I.. Design, synthesis and antitrypanosomal activity of some nitrofurazone 1,2,4-triazolic bioisosteric analogues. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, v. 121, p. 553-560, . Web of Science Citations: 10. (11/11499-0, 12/21865-7, 11/17357-3)

TAVARES, MAURICIO T.; PRIMI, MARINA C.; SILVA, NUNO A. T. F.; CARVALHO, CAMILA F.; CUNHA, MICAEL R.; PARISE-FILHO, ROBERTO. Using an in Silico Approach To Teach 3D Pharmacodynamics of the Drug-Target Interaction Process Focusing on Selective COX2 Inhibition by Celecoxib. Journal of Chemical Education, v. 94, n. 3, p. 380-387, . Web of Science Citations: 4. (13/15947-3)

SERAFIM, RICARDO A. M.; PERNICHELLE, FILIPE G.; FERREIRA, ELIZABETH I.. The latest advances in the discovery of nitric oxide hybrid drug compounds. EXPERT OPINION ON DRUG DISCOVERY, v. 12, n. 9, p. 941-953, . Web of Science Citations: 10. (16/03124-0)

SANTOS, S. S.; GONZAGA, R. V.; SILVA, J. V.; SAVINO, D. F.; PRIETO, D.; SHIKAY, J. M.; SILVA, R. S.; PAULO, L. H. A.; FERREIRA, E. I.; GIAROLLA, J.. Peptide dendrimers: drug/gene delivery and other approaches. Canadian Journal of Chemistry, v. 95, n. 9, p. 907-916, . Web of Science Citations: 9. (15/19438-1, 16/11555-1)

BONIFACE, PONE KAMDEM; FERREIRA, ELIZABETH IGNE. Flavonoids as efficient scaffolds: Recent trends for malaria, leishmaniasis, Chagas disease, and dengue. Phytotherapy Research, . Web of Science Citations: 0. (17/01249-3)

GONZAGA, RODRIGO VIEIRA; SANTOS, SORAYA DA SILVA; DA SILVA, JOAO VITOR; PRIETO, DIEGO CAMPOS; SAVINO, DEBORA FELICIANO; GIAROLLA, JEANINE; FERREIRA, ELIZABETH IGNE. Targeting Groups Employed in Selective Dendrons and Dendrimers. PHARMACEUTICS, v. 10, n. 4, . Web of Science Citations: 0. (15/19438-1)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

ANDRADE, Carolina Horta. Planejamento racional de novos tuberculostáticos com base na estrutura das enzimas enoil redutase e timidina monofosfato quinase do Mycobacterium tuberculosis. 2009. 245f. Tese (Doutorado) – Faculdade de Ciências Farmacêuticas. Universidade de São Paulo (USP). São Paulo. (06/58502-8)

Patent applications

PRÓ-FÁRMACO DENDRIMÉRICO, PROCESSO PARA SUA PREPARAÇÃO E COMPOSIÇÕES CONTENDO OS MESMOS PI0705122-0 - Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Universidade de São Paulo (USP). Elizabeth Igne Ferreira; Jeanine Giarolla - October 2007, 17

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