Dentist graduated from São Paulo State University Júlio de Mesquita Filho (UNESP), Araraquara campus, in 2002, with a Master's degree (2005) and a PhD (2009) in Pharmacology from the Federal University of São Paulo (UNIFESP). During her PhD, she completed a sandwich internship at the University of Virginia (2007) and, more recently, a sabbatical at the Seattle Children's Research Institute (2024).She served as treasurer of the Brazilian Society of Physiology (2015-2016) and the Federation of Experimental Biology Societies (FeSBE) (2017-2021), and as the first secretary of the same Federation (2021-2023). Currently, she is an Associate Professor 3 in the Department of Pharmacology at the Institute of Biomedical Sciences of the University of São Paulo (USP).Her research focuses on how the central nervous system regulates respiration in mammals, with an emphasis on identifying neuronal networks in rodents through electrophysiological and neuroanatomical methods. Her work also investigates alterations in these networks in experimental models of neurodegenerative diseases, particularly Parkinson's Disease.In addition to her academic career, she is the mother of Luísa (17 years old) and Laura (13 years old). (Source: Lattes Curriculum)
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Parkinson's disease (PD) is a neurodegenerative disease characterized by the death of dopaminergic neurons in the compact portion of the Substantia Nigra (SNc) which promotes the classic motor symptoms that are related to movement: rest tremor, rigidity, bradykinesia and postural instability. Although these symptoms are responsible for the diagnosis of the disease and are the therapeutic …
Parkinson's disease (PD) is a neurodegenerative disease that affects approximately 1% of the population over 60 years. It is characterized by classic motor symptoms such as bradykinesia, tremors and postural instability. In addition, there are also autonomic non-motor symptoms (constipation, orthostatic hypotension), cognitive and respiratory changes that greatly impair patients' quality …
Parkinson's disease (PD) is a neurodegenerative disorder characterized by progressive loss of dopaminergic neurons in the substantia nigra compacta (SNc). The main motor symptoms are tremor at rest, bradykinesia, classic rigidity and postural instability. However, we can observe non-motor symptoms as neuropsychiatric, sleep and breathing disorders. Neuroanatomical studies show that the nu…
Breathing automaticity and chemoreception are inseparable neural processes. The retrotrapezoid nucleus (RTN), a group of glutamatergic neurons that express the transcription factor Phox2b, may be a crucial nodal point through which breathing automaticity is regulated to maintain CO2 constant. Additional evidence that RTN neurons have central respiratory chemoreceptor properties is present…
(Only some records are available in English at this moment)
Parkinson's Disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the Substantia Nigra (SN) and the presence of classic motor symptoms. However, in PD, there are also other symptoms, and among them, we have respiratory changes that result from degeneration occurring in neural groups involved in the control of breathing, such as the preBötzinger C…
Parkinson's disease (PD) is a neurodegenerative disease characterized by a reduction in the number of dopaminergic neurons in the substantia nigra pars compacta (SNpc). Patients with PD present classic motor symptoms, exemplified by tremors and postural instability, and non-classical symptoms such as sleep disturbances and respiratory deficit, which are very little investigated. Recent st…
Parkinson's Disease (PD) is a neurodegenerative disorder that is associated with the loss of dopaminergic neurons in the substantia nigra compacta (SNpc) leading to a reduction of dopamine in the nigrostriatal pathway. The motor symptoms are characterized by tremor and bradykinesia while the non-classic symptoms include cognitive deficits, sleep disorders, sensorial dysfunction and breath…
Parkinson's Disease (PD) is a neurodegenerative disorder characterized by the accumulation of intracellular protein and the progressive and irreversible loss of dopaminergic neurons of the substantia nigra pars compacta (SNpc), which leads to a decrease in the dopamine in the striatum. The deficiency of this neurotransmitter leads to the classic motor symptoms of PD, such as tremors and p…
Parkinson's disease (PD) is a neurodegenerative disorder characterized by reduction in the number of dopaminergic neurons in the substantia nigra pars compacta (SNpc). PD patients have classical motor symptoms exemplified by tremors and postural instability, and non-classical symptoms such as sleep disorders and respiratory deficit, that little is known. Recent studies from our laboratory…
(Only some records are available in English at this moment)
Parkinson's disease (PD) is a neurodegenerative disorder characterized by classic motor symptoms, such as tremors and postural instability. In addition, PD can present with non-classical symptoms, which may include respiratory deficits, one of the leading causes of death in affected individuals. Previous studies have shown that the respiratory deficits observed in PD may be linked to dama…
Parkinson's disease (PD) is a neurodegenerative disease characterized by the death of dopaminergic neurons in the compact portion of the Substantia Nigra (SNc) which promotes the classic motor symptoms that are related to movement: rest tremor, rigidity, bradykinesia and postural instability. Although these symptoms are responsible for the diagnosis of the disease and are the therapeutic …
Parkinson´s disease (PD) is a neurodegenerative disorder characterized by progressive loss of dopaminergic neurons in the substantia nigra compacta (SNpc). We can observe non-motor symptoms as neuropsychiatric, sleep and breathing disorders. It was noticed in post-mortem humans brains and in 6-hydroxydopamine (6-OHDA) rat model of PD a significant reduction of neurokinin 1 receptor (NK1r)…
Parkinson's disease (PD) is a disorder characterized by motor and non-motor symptoms, such as respiratory deficits and is associated with loss of dopaminergic neurons in the compact part of the substantia nigra (SNc). However, other brainstem neurons may also be degenerated, contributing to the appearance of non-motor abnormalities. Previous study showed a decrease in the number of phox2b…
| 2 / 2 | Ongoing grants |
| 6 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 20 / 17 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 3 | Completed scholarships abroad |
| 34 / 31 | All research grants and scholarships |
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CV Lattes
ORCID