Regina Celia Galvao Frem
CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Araraquara. Instituto de Química (IQ) (Institutional affiliation for the last research proposal) Birthplace: Brazil
graduation at Bacharelado Em Química Com Atribuições Tecnológica from Universidade Estadual Paulista Júlio de Mesquita Filho (1980), graduation at Licenciatura Em Ciências Con Habilitação Em Químic from Universidade Estadual Paulista Júlio de Mesquita Filho (1987) and doctorate at Química from Universidade Estadual Paulista Júlio de Mesquita Filho (1992). Has experience in Chemistry, acting on the following subjects: paládio (ii), paládio(ii), atividade biológica, pirazóis and palladium(ii). (Source: Lattes Curriculum)
- Metal Organic Frameworks (MOFs) and CO2: a chemical approach for the environmental issue, AP.R
Abstract
Carbon dioxide is one of the more important gases responsible for greenhouse. Today global emissions of CO2 are in the order of 49 billion tons. In this context, the goal of this project is to develop two different strategies so they can, in the near future, constitute in alternative methods for the carbon dioxide reduction in the atmosphere. The first of them focuses on the synthesis o...
- Pd(II) compounds: synthesis, cytotoxicity, and DNA binding studies, AP.R
Abstract
This work deals with the synthesis, characterization, cytotoxicity evaluation and DNA binding studies involving chelated compounds of the type [Pd(N-C)(X)(L)] and [PdX2(N-S)] {N-C = C2,N-bzox, C2,N-mbz, C2,N-bzan (bzox=benzaldehydeoxime, mbz = N-benzylidenemethylamine, bzan = N-Benzylideneaniline); N-S = 1-thiocarbamoylpyrazoles; L = thiourea-type ligands, X=Cl, Br, I, SCN}. The compoun...
- Discrete metallosupramolecules and metal organic frameworks (MOFs): synthesis, characterization and properties, AP.R
Abstract
The main goal of the project is to synthesize cyclic and discrete inorganic species and porous coordination polymers (Metal Organic Frameworks, MOFs) containing exopolidentate ligands and divalent transition metal such as Pd, Ni, Cu, Cd, Mn, Co and Zn. Similar studies using trivalent luminescent lanthanide ions (Eu, Tb, Tm, Sm) and O-donor ligands will also be realized. The classes of ...
- Luminescent devices based on coordination polymers, BP.DR
Abstract
In this work, luminescent coordination polymers will be obtained and characterized aiming application in chemical sensing and light emitting devices. More specifically, Metal-Organic Frameworks (MOFs) are coordination polymers that contain cavities in the structure, and form a class of multifunctional porous materials. Infinite coordination polymers (ICPs) are similar to MOFs, but have ...
- Films based in MOFs (metal-organic frameworks) for adsorption of organic dyes and metal ions, BP.IC
Abstract
Metal-Organic Frameworks (MOFs) are highly porous and selective materials known as inorganic polymer structures in which metal clusters are connected by organic spacers. This new class of materials has been highlighted as adsorbent material of heavy metals and organic dyes. Contamination of water from industrial effluents containing such substances is a concern because its harmful effec...
- MOFs (metal-organic frameworks) for extraction of lanthanide ions (iii) and heavy metals, BP.IC
Abstract
Lanthanide (III) ions are important in several current technological applications, such as in the catalytic and electronics industries. However, these metals have relatively low abundance in Earth's crust. In addition, there is a growing concern about the disposal of these materials into the environment since the environmental impact and toxicity are not yet known in detail. For this re...
(Only some records are available in English at this moment)
- Synthesis of gold and silver nanoparticles using natural reducing agents, BP.IC
Abstract
In this work it will be obtained and characterized gold and silver nanoparticles using natural reducing agents. The compounds will be synthesizes by conventional and microwave synthetic routes. Different experimental parameters will be investigated such as temperature, ligand addition order, stirring time and so on. The obtained specie will be characterized by vibrational and electronic...
- Preparation of aluminium MOFs of the CAU-10 type and use in catalysis of CO2 cicloaddition, BP.IC
Abstract
The goal of the project is to synthesize and to characterize the CAU-10-H, CAU-10-CH3 and CAU-10-NO2 MOFs and to use as heterogeneous catalysts in the reaction between CO2 and ethylene oxide in order to obtain the corresponding carbonate. In the next step of the work, the ethylene carbonate will be used as precursor material for the obtention of ethyleneglicol by ethoxylation reaction.
- Synthesis, characterization and catalytic application of metal-organic framework 801 and 802, BP.IC
Abstract
The major worry with the environmental impacts due to industrial production pass trough alternative studies for the production of ethylene glycols, because the classic method, ethoxylation reaction between an epoxide and ROH group, consumes a lot of energy and water, a vital resource for our society. These glycols are very important because they are used as raw materials for various ind...
(Only some records are available in English at this moment)
| 4 / 3 | Completed research grants |
| 7 / 7 | Ongoing scholarships in Brazil |
| 15 / 6 | Completed scholarships in Brazil |
| 26 / 16 | All research grants and scholarships |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | 11 |
| Citations | 77 |
| Cit./Article | 7.0 |
| Data from Web of Science | |
DA SILVA, PATRICIA B.; BONIFACIO, BRUNA V.; FREM, REGINA C. G.; GODOY NETTO, ADELINO V.; MAURO, ANTONIO E.; DA COSTA FERREIRA, ANA M.; LOPES, ERICA DE O.; RADDI, MARIA S. G.; BAUAB, TAIS M.; PAVAN, FERNANDO R.; et al. A Nanostructured Lipid System as a Strategy to Improve the in Vitro Antibacterial Activity of Copper(II) Complexes. Molecules, v. 20, n. 12, p. 22534-22545, DEC 2015. Web of Science Citations: 6. (13/14957-5, 13/09265-7)
BARRA, CAROLINA V.; ROCHA, FILLIPE V.; MOREL, LAURENT; GAUTIER, ARNAUD; GARRIDO, SAULO S.; MAURO, ANTONIO E.; FREM, REGINA C. G.; NETTO, ADELINO V. G.. DNA binding, topoisomerase inhibition and cytotoxicity of palladium(II) complexes with 1,10-phenanthroline and thioureas. Inorganica Chimica Acta, v. 446, p. 54-60, MAY 1 2016. Web of Science Citations: 20. (14/11340-0)
DA SILVA, CRISTIANA; RIBEIRO, LEONARDO B.; FURUNO, CAIO C.; DA CUNHA, GISLAINE A.; DE SOUZA, RONAN F. F.; NETTO, ADELINO V. G.; MAURO, ANTONIO E.; FREM, REGINA C. G.; FERNANDES, JOSE A.; ALMEIDA PAZ, FILIPE A.; et al. Pyrazolyl Pd(II) complexes containing triphenylphosphine: Synthesis and antimycobacterial activity. Polyhedron, v. 100, p. 10-16, NOV 4 2015. Web of Science Citations: 7. (12/15486-3)
DA SILVA, PATRICIA B.; DE SOUZA, PAULA C.; FIORAMONTI CALIXTO, GIOVANA MARIA; LOPES, ERICA DE O.; FREM, REGINA C. G.; NETTO, ADELINO V. G.; MAURO, ANTONIO E.; PAVAN, FERNANDO R.; CHORILLI, MARLUS. In Vitro Activity of Copper(II) Complexes, Loaded or Unloaded into a Nanostructured Lipid System, against Mycobacterium tuberculosis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, v. 17, n. 5, MAY 2016. Web of Science Citations: 1. (13/14957-5, 13/09265-7)
DE MOURA, THALES R.; CAVALCANTI, SAHRA L.; DE GODOY, PAULO R. D. V.; SAKAMOTO-HOJO, ELZA T.; ROCHA, FILLIPE V.; DE ALMEIDA, EDUARDO T.; DEFLON, VICTOR M.; MAURO, ANTONIO E.; NETTO, ADELINO V. G.. Synthesis, characterization and antitumor activity of palladium(II) complexes of imidazolidine-2-thione. TRANSITION METAL CHEMISTRY, v. 42, n. 6, p. 565-574, SEP 2017. Web of Science Citations: 6. (12/15486-3, 16/17711-5, 09/54011-8)
DA SILVA, C.; FERREIRA, J. G.; MAURO, A. E.; FREM, R. C. G.; SANTOS, R. H. A.; DA SILVA, P. B.; PAVAN, F. R.; MARINO, L. B.; LEITE, C. Q. F.; NETTO, A. V. G.. Synthesis and antimycobacterial activity of new pyrazolate-bridged dinuclear complexes of the type [Pd(mu-L)(N-3)(PPh3)](2) (PPh3 = triphenylphosphine; L = pyrazolates). Inorganic Chemistry Communications, v. 48, p. 153-155, OCT 2014. Web of Science Citations: 5. (12/15486-3)
BARRA, CAROLINA V.; ROCHA, FILLIPE V.; GAUTIER, ARNAUD; MOREL, LAURENT; QUILLES, MARCELA B.; CARLOS, IRACILDA Z.; TREU-FILHO, OSWALDO; FREM, REGINA C. G.; MAURO, ANTONIO E.; NETTO, ADELINO V. G.. Synthesis, cytotoxic activity and DNA interaction of Pd(II) complexes bearing N `-methyl-3,5-dimethyl-1-thiocarbamoylpyrazole. Polyhedron, v. 65, p. 214-220, NOV 28 2013. Web of Science Citations: 9. (12/15486-3)
ROCHA, FILLIPE VIEIRA; BARRA, CAROLINA VALERIO; MAURO, ANTONIO EDUARDO; CARLOS, IRACILDA Z.; NAUTON, LIONEL; EL GHOZZI, MALIKA; GAUTIER, ARNAUD; MOREL, LAURENT; GODOY NETTO, ADELINO VIEIRA. Synthesis, Characterization, X-ray Structure, DNA Cleavage, and Cytotoxic Activities of Palladium(II) Complexes of 4-Phenyl-3-thiosemicarbazide and Triphenylphosphane. European Journal of Inorganic Chemistry, v. 2013, n. 25, p. 4499-4505, SEP 2 2013. Web of Science Citations: 20. (12/15486-3)
ROCHA, FILLIPE V.; FARIAS, RENAN L.; LIMA, MAURO A.; BATISTA, VICTOR S.; NASCIMENTO-JUNIOR, NAILTON M.; GARRIDO, SAULO S.; LEOPOLDINO, ANDREA M.; GOTO, RENATA N.; OLIVEIRA, ADRIANO B.; BECK, JOHANNES; et al. Computational studies, design and synthesis of Pd(II)-based complexes: Allosteric inhibitors of the Human Topoisomerase-II alpha. Journal of Inorganic Biochemistry, v. 199, OCT 2019. Web of Science Citations: 0. (12/15486-3, 13/20156-5, 16/17711-5, 16/04201-9)
BOZZA, GABRIELA F.; DE FARIAS, RENAN L.; DE SOUZA, RONAN F. F.; ROCHA, V, FILLIPE; BARRA, V, CAROLINA; DEFLON, VICTOR M.; DE ALMEIDA, EDUARDO T.; MAURO, ANTONIO E.; NETTO, ADELINO V. G.. Palladium orthometallated complexes containing acetophenoneoxime: Synthesis, crystal structures and hirshfeld surface analysis. Journal of Molecular Structure, v. 1175, p. 195-207, JAN 5 2019. Web of Science Citations: 3. (12/15486-3, 16/17711-5, 14/11340-0)
DE SOUZA, RONAN F. F.; DA CUNHA, GISLAINE A.; PEREIRA, JOSE C. M.; GARCIA, DANIEL M.; BINCOLETTO, CLAUDIA; GOTO, RENATA N.; LEOPOLDINO, ANDREIA M.; DA SILVA, ISABEL C.; PAVAN, FERNANDO R.; DEFLON, VICTOR M.; et al. Orthopalladated acetophenone oxime compounds bearing thioamides as ligands: Synthesis, structure and cytotoxic evaluation. Inorganica Chimica Acta, v. 486, p. 617-624, FEB 24 2019. Web of Science Citations: 0. (12/15486-3, 16/17711-5)
NATHÁLIA A. THOMAZELLA; SAHRA C. LEMOS; RONAN F. F. DE SOUZA; RODRIGO A. DE SOUZA; ANTONIO E. MAURO; IRACILDA Z. CARLOS; ADELINO V. G. NETTO. SÍNTESE, CARACTERIZAÇÃO E AVALIAÇÃO DA ATIVIDADE CITOTÓXICA DE COMPOSTOS CICLOPALADADOS CONTENDO COMO LIGANTES BENZALDEIDOXIMA ORTOMETALADA E ETILENOTIOURÉIA. Química Nova, v. 41, n. 10, p. -, Dez. 2018. (12/15486-3)
PROCESSO DE OBTENÇÃO DE NANOESTRUTURAS LIPÍDICAS, NANOESTRUTURAS LIPÍDICAS OBTIDAS E USO DAS MESMAS BR1020150182856 - Universidade Estadual Paulista (UNESP). Patrícia Bento da Silva; Regina Célia Galvão Frem; Adelino Vieira de Godoy Netto; Antonio Eduardo Mauro; Ana Maria da Costa Ferreira; Fernando Rogério Pavan; Clarice Queico Fujimura Leite; Marlus Chorilli - July 2015, 30
METHOD FOR OBTAINING LIPID NANOSTRUCTURES, THUS OBTAINED LIPID NANOSTRUCTURES AND USE THEREOF PCT/BR2016/050168 - Universidade Estadual Paulista (UNESP). Patrícia Bento da Silva; Regina Célia Galvão Frem; Adelino Vieira de Godoy Netto; Antonio Eduardo Mauro; Ana Maria da Costa Ferreira; Fernando Rogério Pavan; Clarice Queico Fujimura Leite; Marlus Chorilli - July 2016, 22