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Barbara Bernardim de Souza

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Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Exatas e de Tecnologia (CCET)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

I completed my Master?s degree in organic chemistry (2013) and then my PhD in synthetic organic chemistry (2017) at the University of São Paulo, Brazil, under the supervision of Prof. Antonio Burtoloso. During my MSc and PhD, I developed skills in the field of organic chemistry, focused in total synthesis (hydroxylated indolizidines and quinolizidines alkaloids with pronounced biological activities as glycosidase inhibitors) and methodology (development of alpha,beta-unsaturated diazoketones and further applications). I am currently a Research Associate in the Department of Chemistry, University of Cambridge working in the interface of Chemistry and Biology (protein/antibody modification, ADCs) under the supervision of Dr. Gonçalo Bernardes. (Source: Lattes Curriculum)

Scholarships in Brazil
Scholarships abroad
FAPESP support in numbers * Updated February 15, 2020
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Scientific publications resulting from Research Grants and Scholarships under the grantee's responsibility (9)

(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)

Publications9
Citations103
Cit./Article11.4
Data from Web of Science

BURTOLOSO, ANTONIO C. B.; SANTIAGO, JOAO V.; BERNARDIM, BARBARA; TALERO, ALEXANDER G.. Advances in the Enantioselective Metal-catalyzed N-H and O-H Insertion Reactions with Diazocarbonyl Compounds. CURRENT ORGANIC SYNTHESIS, v. 12, n. 5, p. 650-659, . Web of Science Citations: 6. (12/22274-2, 13/25504-1, 13/18009-4)

BERNARDIM, BARBARA; COUCH, ERICA D.; HARDMAN-BALDWIN, ANDREA M.; BURTOLOSO, ANTONIO C. B.; MATTSON, ANITA E.. Divergent Roles of Urea and Phosphoric Acid Derived Catalysts in Reactions of Diazo Compounds. SYNTHESIS-STUTTGART, v. 48, n. 5, p. 677-686, . Web of Science Citations: 11. (13/18009-4, 13/25504-1, 13/50312-9, 12/22274-2)

BURTOLOSO, ANTONIO C. B.; DIAS, RAFAEL M. P.; BERNARDIM, BARBARA. alpha,beta-Unsaturated Diazoketones as Useful Platforms in the Synthesis of Nitrogen Heterocycles. ACCOUNTS OF CHEMICAL RESEARCH, v. 48, n. 4, p. 921-934, . Web of Science Citations: 35. (12/22274-2, 13/25504-1)

MATOS, MARIA J.; NAVO, CLAUDIO D.; HAKALA, TUULI; FERHATI, XHENTI; GUERREIRO, ANA; HARTMANN, DAVID; BERNARDIM, BARBARA; SAAR, KADI L.; COMPANON, ISMAEL; CORZANA, FRANCISCO; et al. Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine-Selective Protein Modification and Charge Modulation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, v. 58, n. 20, p. 6640-6644, . Web of Science Citations: 1. (15/07509-1, 17/13168-8)

LINDSTEDT, PHILIP R.; APRILE, FRANCESCO A.; MATOS, MARIA J.; PERNI, MICHELE; BERTOLDO, JEAN B.; BERNARDIM, BARBARA; PETER, QUENTIN; JIMENEZ-OSES, GONZALO; KNOWLES, TUOMAS P. J.; DOBSON, CHRISTOPHER M.; et al. Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification. ACS CENTRAL SCIENCE, v. 5, n. 8, p. 1417-1424, . Web of Science Citations: 0. (17/13168-8)

BERNARDIM, BARBARA; BURTOLOSO, ANTONIO C. B.. A two-step synthesis of the bioprotective agent JP4-039 from N-Boc-L-leucinal. Tetrahedron, v. 70, n. 20, p. 3291-3296, . Web of Science Citations: 6. (12/22274-2, 09/54040-8, 12/04685-5)

BERNARDIM, BARBARA; HARDMAN-BALDWIN, ANDREA M.; BURTOLOSO, ANTONIO C. B.. LED lighting as a simple, inexpensive, and sustainable alternative for Wolff rearrangements. RSC ADVANCES, v. 5, n. 18, p. 13311-13314, . Web of Science Citations: 11. (12/22274-2, 13/25504-1)

BERNARDIM, BARBARA; CAL, PEDRO M. S. D.; MATOS, MARIA J.; OLIVEIRA, BRUNO L.; MARTINEZ-SAEZ, NURIA; ALBUQUERQUE, INES S.; PERKINS, ELIZABETH; CORZANA, FRANCISCO; BURTOLOSO, ANTONIO C. B.; JIMENEZ-OSES, GONZALO; et al. Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents. NATURE COMMUNICATIONS, v. 7, . Web of Science Citations: 31. (12/22274-2, 13/25504-1, 15/07509-1)

BERNARDIM, BARBARA; MATOS, MARIA J.; FERHATI, XHENTI; COMPANON, ISMAEL; GUERREIRO, ANA; AKKAPEDDI, PADMA; BURTOLOSO, ANTONIO C. B.; JIMENEZ-OSES, GONZALO; CORZANA, FRANCISCO; BERNARDES, GONCALO J. L.. Efficient and irreversible antibody-cysteine bioconjugation using carbonylacrylic reagents. Nature Protocols, v. 14, n. 1, p. 86-99, . Web of Science Citations: 2. (13/25504-1, 15/07509-1, 17/13168-8)

Academic Publications

(References retrieved automatically from State of São Paulo Research Institutions)

SOUZA, Barbara Bernardim de. Novas metodologias em síntese orgânica empregando o rearranjo de Wolff em diazocetonas insaturadas. 2017. Tese (Doutorado) – Instituto de Química de São Carlos. Universidade de São Paulo (USP). São Carlos.

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