CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Ciências Biológicas Modalidade Médica from Universidade Estadual Paulista Júlio de Mesquita Filho (1998), master's at Microbiology from Universidade de São Paulo (2001) and ph.d. at Microbiology from Universidade Federal de São Paulo (2006). Has experience in Microbiology, focusing on Microbiology (Source: Lattes Curriculum)
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Escherichia coli are characterized by harboring both commensal and / or symbiotic strains, as well as strains that are pathogenic to the intestinal and extraintestinal sites of humans and warm-blooded animals. This plurality of behavior is due, on the one hand, to the fact that most of its virulence determinants are encoded in mobile genetic elements and, on the other hand, the extreme pe…
The species Escherichia albertii comprises the newest member of the genus Escherichia and is associated with sporadic cases, as well as outbreaks of diarrhea in several countries, including Brazil. One of the main characteristics of virulence observed in E. albertii isolates is the formation of the attaching and effacing lesion (AE), which is characterized by intimate bacteria adherence t…
Enteropathogenic Escherichia coli (EPEC), an important diarrheal pathotype that affects children and adults, has the hallmark virulence ability to cause a histopathologic lesion characterized by microvillus destruction on the infected epithelial cells and the formation of a pedestal-like structure rich in F-actin and other cytoskeleton elements, termed attaching and effacing lesion. This …
(Only some records are available in English at this moment)
Collectively, Escherichia coli isolates associated with gastrointestinal tract infections are known as diarrheagenic E. coli (DEC), and based on their virulence factors, DEC can be subgrouped into six distinct pathotypes. From an epidemiological point of view, enteropathogenic E. coli (EPEC) and enteroaggregative E. coli (EAEC) are the most frequently DEC pathotypes isolated from stool sa…
Bacterial adherence to epithelial cells is an indispensable step in the pathogenicity, allowing the establishment of several pathogens in their hosts. Among the bacteria causing infections in the gastrointestinal tract, we can highlight the enteroaggregative Escherichia coli (EAEC) as an important agent of acute and persistent diarrhea. The main phenotypic feature of EAEC isolates is thei…
(Only some records are available in English at this moment)
Pathogenic Escherichia coli isolates can lead to intestinal infections, caused by Diarrheagenic E. coli (DEC), or outside the gastrointestinal tract, caused by Extraintestinal Pathogenic E. coli (ExPEC). Among DEC pathotypes, enteroaggregative E. coli (EAEC) is frequently isolated from cases of acute and persistent diarrhea in children and adults in Brazil. EAEC isolates are identified by…
Enteroaggregative Escherichia coli (EAEC) is an important agent of diarrheal disease affecting both children and adults. The main characteristics of this pathogen are their ability to adhere to epithelial cells in a characteristic pattern termed aggregative adherence pattern (AA), which is characterized by the organization of bacteria in a way that resembles stacked bricks, and its high e…
Pathogenic Escherichia coli is subdivided according to the type of disease that they cause into diarrheagenic E. coli (DEC), associated with intestinal infections, and extra-intestinal E. coli (ExPEC), which causes several infections, among which we can highlight: urinary tract infections (UTI), sepsis and meningitis. Among the DEC pathotypes, enteropathogenic E. coli (EPEC) and enteroagg…
(Only some records are available in English at this moment)
Although described as diarrheagenic Escherichia coli, several studies in the literature are accumulating evidence that enteroaggregative E. coli (EAEC) isolates can be associated with extraintestinal infections, such as bacteremia and urinary tract infections. Here we analyzed the presence of the five extraintestinal pathogenic E. coli (ExPEC) classificatory genes (papA and/or papC, afa/d…
Atypical enteropathogenic E.coli (aEPEC) are one of the most prevalent diarrheagenic E. coli pathotype implicated as a cause of diarrhea in children and adults worldwide. The hallmark of aEPEC infection is the formation of a lesion termed attaching and effacing (AE) lesion, which promotes the intimate adherence of the bacteria to the host cells, erasure of brush border microvilli and form…
| 1 / 1 | Ongoing grants |
| 5 / 4 | Completed research grants |
| 4 / 4 | Ongoing scholarships in Brazil |
| 14 / 11 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 26 / 22 | All research grants and scholarships |
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