Bachelor Degree Biological Sciences (1998) and Masters in Genetics and Evolution (2001), both from the Federal University of São Carlos (UFSCar), Ph.D. in Medical Sciences (2006), Program of Clinical Medicine, Faculty of Medicine, University of São Paulo Ribeirão Preto (FMRP-USP). Postdoctoral Fellow at the Center for Cell Therapy - CTC (2007). Scientific and Technological Research, hired by the Blood Center Foundation of Ribeirão Preto - FUNDHERP (2007-Present). Member of the Cell Therapy Center - CTC (CEPID-FAPESP) and of the National Institute of Science and Technology in Stem Cell and Cell Therapy - INCTC. Has experience in the area of Biochemistry and Immunology, with emphasis on Molecular and Cellular Biology, working mainly with gene expression studies on a large-scale (Microarray) aimed at understanding the biology of adult stem cells (Hematopoietic and Mesenchymal), pluripotent SC , blood cancers (leukemias and lymphomas), and differentiation of T lymphocytes and Treg. Winner of several awards, including the Young Scientist Award from CNPq (2005). Scientific Advisor of the Foundation for Research Support of the State of São Paulo - FAPESP (2009-Present). Academic Editor of the International Journal PLoS ONE (2011-Present). Elected Affiliate Member of the Brazilian Academy of Sciences - ABC (2012 / 2013-2017). (Source: Lattes Curriculum)
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Metabolic and oxygen gradients influence the biology and distribution of tumor, stromal, and immune cells within the Tumor MicroEnvironment (TME), as well as in protective niches, such as the Bone Marrow and Lymph Nodes. These gradients orchestrate tumor escape mechanisms, reducing the efficacy of anti-cancer drugs, as well as immunotherapies, such as checkpoint inhibitor and adoptive cel…
The diagnostic classification and prognostic risk stratification of Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemias (AML) are fundamental for the selection of more effective therapeutic approaches. The resistance of leukemic blasts to standard chemotherapy in the induction phase may result in an inadequate response or failure to achieve complete remission (CR), constituting on…
Mouse Embryonic Stem Cells (ESC) can be derived from internal cellular mass of blastocyst in pre and post-implantation, originating, respectively, mESC or EpiSCs. In vitro, these cells present different functional, phenotypic, epigenetic and molecular characteristics. The mESC (Naïve) are considered more primitive and undifferentiated, meanwhile the EpiSCs (Primed) would be already prepar…
The head and neck cancer (HNC) is a worldwide public health issue, affecting thousands of people each year, whose mortality rate has remained virtually unchanged in the last decades. In order to seek new and more effective therapeutic approaches against cancer, microRNAs (miRs) have received great attention in view of the ability of these molecules to bind to a hundreds of target transcri…
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Pluripotency and self-renewal are distinctive properties of embryonic stem cells (ESCs). microRNAs (miRs) play important roles in the post-transcriptional control of gene expression, by targeting multiple mRNA, and have been implicated in the maintenance of pluripotent cells characteristics. Many miRs effects are attributed to cell cycle regulation, in line with the intimate link between …
Pluripotency and the ability to self-renew are distinctive properties of embryonic stem cells (ESCs), that confer them a great potential in regenerative medicine. The understanding of the regulatory networks acting on ESCs, led to the identification of a core set of transcription factors (TFs) able to control pluripotency, leading to the discovery that somatic cells could be reprogramed i…
| 1 / 1 | Ongoing research grants |
| 2 / 2 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 11 / 9 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 17 / 15 | All research grants and scholarships |
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CV Lattes
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